Cybb (NM_007807) Mouse Untagged Clone

CAT#: MC204867

Cybb (untagged) - Mouse cytochrome b-245, beta polypeptide (Cybb), (10ug)


  "NM_007807" in other vectors (4)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Cybb
Synonyms C88302; Cgd; CGD91-phox; Cyd; gp91-1; gp91phox; Nox2
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>BC071229
GGCAGAACCAACACTTAACCTTTGCTAACATGGGGAACTGGGCTGTGAATGAAGGACTCTCCATCTTTGT CATTCTGGTGTGGTTGGGGCTGAATGTCTTCCTCTTTATCAACTACTACAAGGTTTATGATGATGGGCCT AAGTATAATTATACTCGAAAACTCCTTGGGTCAGCACTGGCTCTGGCCCGGGCACCTGCAGCCTGCCTGA ATTTCAACTGTATGCTGATCCTGCTGCCAGTGTGTCGAAATCTGCTCTCCTTTCTCAGGGGTTCCAGTGC GTGTTGCTCGACAAGGATTCGAAGACAACTGGACAGGAACCTCACTTTCCATAAGATGGTAGCTTGGATG ATAGCACTGCACACCGCCATCCACACAATTGCACATCTCTTCAACGTTGAGTGGTGTGTGAATGCCAGAG TCGGGATTTCTGACCGGTATTCAATAGCTCTCTCTGACATCGGTGACAATGAGAACGAAGAGTATCTCAA TTTTGCTAGAGAAAAAATCAAGAACCCTGAAGGGGGCCTGTATGTGGCCGTGACTCGGTTGGCTGGGATC ACAGGAATTGTCATCACACTGTGTCTCATATTGATTATCACATCCTCTACCAAAACCATTCGGAGGTCTT ATTTTGAAGTGTTCTGGTATACACACCATCTCTTTGTGATCTTCTTCATCGGCCTTGCCATCCATGGAGC TGAACGAATTGTACGTGGACAGACTGCGGAGAGTTTGGAAGAGCATAATTTAGATATCTGTGCAGACAAA ATCGAAGAATGGGGAAAAATAAAGGAGTGCCCAGTACCAAAGTTCGCTGGAAACCCTCCTATGACTTGGA AATGGATAGTGGGTCCTATGTTCCTGTACCTTTGTGAGAGGTTGGTTCGGTTTTGGCGATCTCAGCAAAA GGTGGTCATCACCAAGGTGGTCACCCACCCTTTCAAAACCATTGAGCTTCAGATGAAGAAGAAGGGATTC AAGATGGAGGTGGGACAGTACATTTTTGTCAAGTGCCCCAAGGTATCCAAGTTAGAATGGCACCCATTCA CACTGACCTCTGCTCCTGAGGAAGACTTTTTTAGCATCCATATCCGTATTGTGGGAGACTGGACGGAGGG GCTATTCAATGCTTGTGGCTGTGATAAGCAGGAGTTCCAAGATGCCTGGAAACTACCTAAGATAGCAGTT GATGGACCCTTTGGTACAGCCAGTGAAGATGTGTTCAGCTATGAGGTGGTGATGTTAGTGGGAGCCGGGA TTGGAGTCACGCCCTTTGCCTCCATTCTCAAGTCTGTCTGGTACAAATATTGTGATAATGCCACCAGTCT GAAACTCAAAAAGATCTACTTCTACTGGCTGTGCAGGGACACGCATGCCTTTGAGTGGTTTGCAGACCTG CTGCAGCTGCTGGAGACCCAGATGCAGGAAAGGAACAATGCCAACTTCCTCAGCTACAATATCTACCTTA CTGGCTGGGATGAATCTCAGGCCAATCACTTTGCTGTGCACCATGATGAGGAGAAAGATGTGATCACAGG CCTAAAACAGAAGACTCTGTATGGACGGCCCAACTGGGATAACGAGTTCAAGACCATTGCAAGTGAACAC CCTAACACCACAATAGGCGTTTTCCTGTGTGGCCCTGAAGCCTTGGCTGAAACTCTCAGTAAACAGAGCA TCTCCAACTCAGAATCCGGCCCGCGTGGAGTCCACTTCATTTTCAACAAGGAAAACTTCTAACTCCGCTC TTTCACCAGGAAACCAGTGTATGCTGCCAAATGTCCCAGTAATGCTGGTTGGTTGTAGGAGAGAAGGAGG AAAGGAAATCACAATGACACAGGCCCCCTAAAAGGAATTCCAAAGATCCTTACTAGTCATCTGTCATATT GCATGGAACTTCATGGTTTCAGAGCACTTTTTACATACATAGTTATGCATTGTTTCACATTTCCCTTTGA CATGCCAGAAGAGGGTAAGGCAAAAGCATTTTCTGGGACTCTCTCTAGGATAAACAATAGGATCTCAAAT GAGTTCCACACCTTCCTTCCAATTCAGAAGTTGAAACCACACCTAAGCCATCTGACTCTGGGTGTGGTCA CCTTTTCACCTTTAATACCAGGTTGTCTCAAGCCTCAGTTTTTATACTATCCACCAACAAAAAAGCAAGT CAAAGAAGAGCTCATCATTCTTAGCTGTTGTTTTCTCTTTAACCTTAGCATCATGCTAAAGGAAACTTTT TAAATAGAGGAGATAGTGATGCTGATGGTGACTTAATACTTCCTAAATGACAGTATCGGCACAGAAGTAT ATTCCAGTTTTATCAGCACAACAGTTTAACTGGGTCAGAGATTATTCCTAGTAAGAAATATTAGACTGAT TGGAGTTAAAGTAGCACTCTACATTTACCATGGTGTTTGGCAGAATTGGTGTTCAAGGTCAGTTTATTGA ATGAATGAATGAATGATTGAACAAATAGATGCAAACATTCAGAACTATATCATAATGGAATGTATGGCCA GAGACAGAATTACCCTTCTGTTTCTTTTACACACCAAAGTATCCTGATTCCCCTGGGAGTAGAGAGAAAG ATATGAACCAATAGGGAGAGTCAGGCCATTCTACTGGTATTCATCCAACTGTCATTTGAAGGGAGGAGGC ATGAATTCAGAGACCTATTCTCCTATGATGATGGTGGCTAACACTTCTAGTTCCAGTCTGTAAGCTGAAA AAGAAGAACACATTTATTTACTGACAGAAATGATCTGCTCCAGCCAAACTTTGAACTGAATTCTAAGAAA TGTATACATGATAATACATATCCTGCTTAGAATCCATTTCTTCTTTGGCTTAAATACCTATACAAATAGA TCTTATGTGCATAGACAATAACTTGTTTTTTTTTTTTTAATTGCAGCATTTTCATCACCACTAGTACCAG CATCACCATCTTCCTAAAATATAAATTTTAGAAACTGTAATCCCCAAATAACTGGGTTAAGAGTAAAATC ACATCCGATATTTTATGGGCATCCAGAAATGCAAGACAGAGTCTAGATGACTGCTAGACTAGTCACATGT GAAAAAAAAAAAAAAAAA
Restriction Sites RsrII-NotI     
ACCN NM_007807
ORF Size 1713 bp
Insert Size 1713
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Reference Data
RefSeq BC071229, AAH71229
RefSeq Size 3098
RefSeq ORF 1713
Locus ID 13058
Gene Summary This gene encodes the heavy chain component of a heterodimeric transmembrane ion transporter composed of both a heavy and a light chain. This transporter mediates the transfer of electrons from nicotinamide adenine dinucleotide phosphate (NADPH) to oxygen to generate superoxide. This reaction is important in the innate immune response to pathogens. However, increased activity of the encoded protein also leads to the generation of reactive oxygen species that result in oxidative stress and can cause tissue damage. Conversely, loss of function of the related gene in human causes chronic granulomatous disease. Alternative splicing results in multiple transcript variants, although the full-length nature of some of these variants has not been determined. [provided by RefSeq, May 2013]

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