Ptges2 (NM_133783) Mouse Untagged Clone

CAT#: MC205660

Ptges2 (untagged) - Mouse prostaglandin E synthase 2 (Ptges2), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Ptges2
• Synonyms: 0610038H10Rik; C79137; Gbf1; Mpges2; Pges2
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC004846
  GCGCCGGCAGAGCGAACATGGCCCAGGCGGCGCGCCTTTCGTGGGTGCTTGTCTCTAGCCGGTGCGCCCT GACTGAGGGGCTGCTCACACGACCCTGGCAGCCGCTCTCGGCACAGAGCCGGGCTGGCTTCACCAGGGTG GCTGCCGGAAGCCGGGGCGCCGCGGTCCGCAAGGGGAGCCCGCGGTTGCTGGGGGCGGCGGCGCTGGCCC TGGGCGGCGCGCTGGGGCTGTACCACACCGTGCGGTGGCACCAGCGTTCCCAGGACCTCCGCGCGGAGCG CTCGGCTGCGCAGCTGCCCCTGTCGAACAGCCTGCAGCTGACCCTGTACCAGTACAAGACATGTCCCTTC TGCAGCAAAGTCCGTGCCTTCCTCGACTTCCACTCCCTGCCCTATCAGGTGGTGGAGGTGAATCCCGTGA GAAGGACTGAGATCAAATTCTCCTCCTACAGGAAAGTGCCCATCTTGGTGGCCCAGGAAGGAGACAGCTT GCAACAGCTCAATGACTCCTCTGTCATCATTAGTGCCCTCAAGACCTACCTGGTTTCAGGGCAGCCCCTG GAAGAGGTCATCACTTATTACCCACCCATGAAGGCCATGAATGACCAGGGCAAGGAGGTGACCGAGTTTT GCAACAAGTACTGGCCCATGCTGGACGAGAAGGAGGCCCAGCAGATGTATGGCGGGAAGGAAGCCAGGAC GGAGGAGATGAAGTGGCGGCAGTGGGCGGATGACTGGCTGGTGCATCTCATCTCTCCCAACGTGTACCGA ACACCCGCTGAGGCCTTGGCTTCCTTCGACTACATTGTCCGTGAGGGCAAGTTTGGGGCTGTGGAGGCTG CCATGGCCAAGTATGTGGGCGCGGCTGCCATGTACCTCATCAGCAAGCGCCTCAAAAGCAGGCACCACCT GCAGGATGATGTACGGGTAGACCTCTATGAAGCAGCCAACAAGTGGGTGACAGCCGTGGGTAAAGACCGG CCATTCATGGGGGGTCAGAAGCCTAACCTTGCTGACCTGGCAGTGTATGGTGTGCTGCGAGTGATGGAGG GTCTGGAGGCCTTCGACGACCTGATGCGACACTCACACATCCAGCCTTGGTACCTGCGGATGGAGCGGGC CATTGAAGAAGCCCCCTCGGTGCATCATGTCAACCCTAGCTGCAAAGACTAGTTGCTAGGGACACAAGAC CTGGACCAGCCCCTGGCTGTGCTCACAGAGGGCAGAGTCATTTTGTCTCTGGTCCACCTAGCCCCCAGTT CTCTGCTTCTGATACTGGACATTTCTAGGGCCCTTGACGCTGAGGACAAGGCCCAAACTTACAGCTGTTC TGTGGGTAAAGGGTCTGGGGTCTCAAAGGCCTACCCTTCAACCCCAGTTCAGAGGCCTGGTCCCCTAACA GGGACTCCTTTTCAACTCTGCTAGGGCCAAGTCCCTTGTTGACAGGGATCAGACTGGCTCCTGCCCTGGA GGAGGGGAAGGCAGTGTGTTAACAAAGCCCCGCCCACATGCCTCCAGGTTTCAGCTCTTCGAAGGTGCCC CTGGGACTATTGTATTTGTAATAAAGGAGAGGTCTGCCACCCCAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: NM_133783
• ORF Size: 1155 bp
• Insert Size: 1155
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC004846, AAH04846
• RefSeq Size: 1598
• RefSeq ORF: 1155
• Locus ID: 96979
• Gene Summary: The protein encoded by this gene is a Golgi membrane-associated prostaglandin E synthase candidate, which is capable of catalyzing the conversion of prostaglandin H2 to prostaglandin E2 in vitro. However, a study using mice deficient of this gene suggests that this enzyme does not contribute to prostaglandin E2 biosynthesis in vivo. This protein is synthesized as a Golgi membrane-bound protein, but its N-terminal hydrophobic region is cleaved off during protein maturation to produce the predominant soluble truncated form that still retains the enzyme activity. This soluble protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE), possibly via an interaction with CAAAT/enhancer-binding protein-beta. [provided by RefSeq, Oct 2009]