Nr0b2 (BC019540) Mouse Untagged Clone

CAT#: MC206305

Nr0b2 (untagged) - Mouse nuclear receptor subfamily 0, group B, member 2 (cDNA clone MGC:28536 IMAGE:4193866), (10ug)


Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Symbol Nr0b2
Synonyms SHP, SHP-1, Shp1
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>BC019540
GATAGCTGGGAAGAAACAGGAACAAGATACTAACCATGAGCTCCGGCCAGTCAGGGGTCTGCCCATGCCA GGGCTCTGCAGGTCGTCCGACTATTCTGTATGCACTTCTGAGCCCCAGCCCCAGGACCAGGCCCGTTGCA CCTGCATCTCACAGCCACTGCCTGTGCCAGCAGCAGCGGCCTGTGCGTCTGTGTGCTCCGCACCGCACCT GCAGGGAGGCCTTGGATGTCCTAGCCAAGACAGTAGCCTTCCTCAGGAACCTGCCGTCCTTCTGCCACCT GCCCCATGAGGATCAGCGGCGGCTGCTAGAGTGCTGCTGGGGCCCTCTCTTCCTGCTTGGGTTGGCCCAG GATGCTGTGACCTTCGAGGTGGCTGAGGCTCCGGTGCCCAGTATACTTAAGAAGATCCTGCTAGAGGAAG CCAGCAGCGGTACCCAGGGTGCCCAGCCATCAGACCGGCCACAACCCTCACTGGCTGCAGTTCAGTGGCT GCAGCGCTGCCTGGAGTCTTTCTGGAGCCTTGAGCTGGGTCCCAAGGAGTATGCGTACCTGAAGGGCACG ATCCTCTTCAACCCAGATGTGCCAGGCCTCCGTGCCTCCTGCCACATCGCACACCTGCAACAGGAGGCTC ACTGGGCACTGTGTGAAGTCTTGGAGCCCTGGTACCCAGCCAGCCAAGGCCGCCTGGCCCGAATCCTCCT CATGGCCTCTACCCTCAAGAACATTCCAGGCACCCTTCTGGTAGATCTCTTCTTCCGCCCTATCATGGGA GACGTTGACATCACTGAACTCCTTGAAGACATGCTTTTGCTGAGGTGACCCGTGGAATGGAGTCTGGTGC CTCCAAAGGGGAGCCTGAAAGGCAGCCCTCAACTCCCCTGGAGCTGCCCTCAGCTCAGCCACACCCCTAG CTCGGACTTCCTTGCTTTGGATACAGTGTACACTACTAACTGTCCAGCAAGCCCTTGATGACTCCCCAAA CCTCCAGGCCAAAATGTCTTTCCCTGCCTGGGTAGGGATGGGAGCAGGAAGCTGTACTTTCAAGCCAGAA TCCCTCCTGACTTTGTACAGAACTAAATTAAGTTATTGTTTTTTGTAATAAAACATATGACCTCCTGAAA AAAAAAAAAAAAA
Restriction Sites RsrII-NotI     
ACCN BC019540
ORF Size 783 bp
Insert Size 783
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq BC019540, AAH19540
RefSeq Size 1133
RefSeq ORF 783
Locus ID 23957
Gene Summary This gene encodes a member of the nuclear hormone receptor family of proteins. The encoded orphan receptor lacks a DNA binding domain but modulates gene expression by interacting with other hormone receptors to competitively inhibit binding of coactivators while also acting as a transcriptional corepressor. The encoded receptor may regulate bile acid synthesis and sexual maturation in males. Homozygous knockout mice exhibit accumulation of bile acids, reduced levels of low density lipoprotein cholesterol (LDL-C), and in male mice, earlier testicular maturation. [provided by RefSeq, Aug 2015]

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