Mlkl (BC023755) Mouse Untagged Clone

CAT#: MC206757

Mlkl (untagged) - Mouse mixed lineage kinase domain-like (cDNA clone MGC:38580 IMAGE:5354568), (10ug)

Specifications

Product Data

• Type: Mouse Untagged Clone
• Tag: Tag Free
• Symbol: Mlkl
• Synonyms: 9130019I15Rik
• Vector: PCMV6-Kan/Neo
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >BC023755
  CCACGCGTCCGGTCGGACAGGTTGGTTTTGAGGACTCTGCTGGAGCATTGCTGCGTTGGCCCAAATTTGA CTTTAGGCGGGAACCGCGGCTGGTGCGGAGTTCCTCCGAGAGGCGAGAGCTTTAAGGTTGCACCAAGGGA GGGGACTCAGGACACCGGGGACCTGCTCCGACCTGGCGTGCATTGTCAACGAGGCAGAAGACCGCGGTCC GGGAGCGGCGGGAGACTGATGATCCTACAGGAACTGAGCGCAGGATAGACCGGACGAGCGCCCCTCGGAG ATCACGTAGAATCCAGTGAGCTGTAGCGCGGCAGGAGGAAGCAGGAGAATCCCAGAATCACAGATTGGAC TTCCTGGAACTTAGGCTATGGATAAATTGGGACAGATCATCAAGTTAGGCCAGCTCATCTATGAACAGTG TGAAAAGATGAAATACTGCCGGAAACAATGCCAGCGTCTAGGAAACCGTGTGCACGGCCTGCTACAGCCT CTCCAGAGACTCCAGGCCCAAGGAAAGAAGAACCTGCCCGATGACATTACTGCTGCCCTGGGCCGTTTTG ATGAAGTCCTGAAGGAGGCTAACCAGCAGATAGAAAAGTTCAGCAAGAAGTCCCATATTTGGAAGTTTGT GAGTGTGGGCAATGATAAGATCCTCTTCCATGAAGTGAATGAGAAGCTGAGAGACGTCTGGGAGGAGCTG TTGCTGCTGCTTCAGGTTTATCATTGGAATACCGTTTCAGATGTCAGCCAGCCAGCATCCTGGCAGCAGG AAGATCGACAGGATGCAGAGGAAGACGGAAATGAAAATATGAAAGTTATCCTGATGCAGTTGCAAATTAG CGTGGAAGAAATCAACAAAACCCTGAAGCAATGCTCACTAAAACCCACACAGGAGATCCCACAAGATCTC CAAATCAAGGAGATTCCAAAGGAACATCTTGGACCTCCGTGGACCAAACTGAAGACAAGTAAAATGAGCA CCATTTATAGAGGAGAGTATCACAGATCTCCAGTTACCATCAAAGTATTCAACAACCCCCAGGCCGAAAG TGTTGGAATAGTGAGGTTCACTTTCAATGACGAGATCAAAACCATGAAGAAATTCGATTCTCCCAACATC TTGCGTATATTTGGGATTTGCATTGATCAAACAGTGAAGCCCCCTGAGTTCTCCATTGTCATGGAGTACT GTGAACTTGGAACCCTGAGGGAACTGCTGGATAGAGAAAAAGACCTCACAATGAGTGTGCGCAGCCTCCT AGTCCTGAGGGCAGCCAGAGGCTTATACAGGCTACACCATTCGGAAACACTCCACAGAAACATCAGCAGC TCCAGTTTCCTCGTAGCCGGAGGCTACCAAGTAAAGCTTGCAGGATTTGAGTTAAGCAAAACACAGAATT CCATCAGCCGGACAGCAAAGAGCACTAAAGCAGAGAGATCCAGTTCAACGATATATGTCTCCCCTGAGAG ACTGAAAAATCCATTTTGCCTTTATGACATAAAAGCTGAAATATATAGCTTTGGAATTGTACTCTGGGAA ATTGCCACTGGAAAGATCCCATTTGAAGGCTGTGATTCTAAGAAGATCCGGGAGCTGGTGGCTGAGGACA AGAAGCAGGAACCAGTGGGTCAGGATTGCCCTGAGTTGTTGCGGGAAATCATTAATGAGTGTCGTGCCCA TGAGCCCTCCCAACGGCCCTCTGTGGACGGAATCTTGGAGAGACTGTCTGCGGTTGAAGAATCCACGGAC AAGAAGGTGTAAGAGGACAAAGTGGACATTTGTCCTTCATATCTGTTAGCAGCATCAACTTATTGCTGGG AGCAAATAGCTTCTTTCTCCCTTGCTTGCTTGCTTTTTTTCTTTCTTTTACTTGAGATGGGATCTCACCA TGTAGCCCCTGAAAACTGTGTAGAACAGGCTGGCTCAAACTCAAGGAAATCTTCCAGTTCTGCCTCCTGA ATGCTGGAATTAAAGGCATAGACCACCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: RsrII-NotI
• ACCN: BC023755
• ORF Size: 1395 bp
• Insert Size: 1395
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC023755, AAH23755
• RefSeq Size: 2020
• RefSeq ORF: 1395
• Locus ID: 74568
• Gene Summary: This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to lack protein kinase activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (Rip3), which is a key signaling molecule in necroptosis pathway. Knockout of this gene in mice showed that it is essential for necroptosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]