GNLY (NM_006433) Human Tagged ORF Clone

CAT#: RC204321L2

Lenti ORF clone of Human granulysin (GNLY), transcript variant NKG5, mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: GNLY
• Synonyms: D2S69E; LAG-2; LAG2; NKG5; TLA519
• Vector: pLenti-C-mGFP
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204321).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_006433
• ORF Size: 435 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_006433.2, NP_006424.2
• RefSeq Size: 751
• RefSeq ORF: 438
• Locus ID: 10578
• Domains: SapB_2, SAPB
• Protein Families: Secreted Protein
• MW: 16.4 kDa
• Gene Summary: The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]