GNLY (NM_006433) Human Untagged Clone

CAT#: SC116116

GNLY (untagged)-Human granulysin (GNLY), transcript variant NKG5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GNLY
• Synonyms: D2S69E; LAG-2; LAG2; NKG5; TLA519
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_006433 edited
  ATGGCTACCTGGGCCCTCCTGCTCCTTGCAGCCATGCTCCTGGGCAACCCAGGTCTGGTC
  TTCTCTCGTCTGAGCCCTGAGTACTACGACCTGGCAAGAGCCCACCTGCGTGATGAGGAG
  AAATCCTGCCCGTGCCTGGCCCAGGAGGGCCCCCAGGGTGACCTGTTGACCAAAACACAG
  GAGCTGGGCCGTGACTACAGGACCTGTCTGACGATAGTCCAAAAACTGAAGAAGATGGTG
  GATAAGCCCACCCAGAGAAGTGTTTCCAATGCTGCGACCCGGGTGTGTAGGACGGGGAGG
  TCACGATGGCGCGACGTCTGCAGAAATTTCATGAGGAGGTATCAGTCTAGAGTTACCCAG
  GGCCTCGTGGCCGGAGAAACTGCCCAGCAGATCTGTGAGGACCTCAGGTTGTGTATACCT
  TCTACAGGTCCCCTCTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006433 unedited
  GTAACAACAGAATTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGAGGCAT
  CTCAGCGGCTGCCCCACCATGGCTACCTGGGCCCTCCTGCTCCTTGCAGCCATGCTCCTG
  GGCAACCCAGGTCTGGTCTTCTCTCGTCTGAGCCCTGAGTACTACGACCTGGCAAGAGCC
  CACCTGCGTGATGAGGAGAAATCCTGCCCGTGCCTGGCCCAGGAGGGCCCCCAGGGTGAC
  CTGTTGACCAAAACACAGGAGCTGGGCCGTGACTACAGGACCTGTCTGACGATAGTCCAA
  AAACTGAAGAAGATGGTGGATAAGCCCACCCAGAGAAGTGTTTCCAATGCTGCGACCCGG
  GTGTGTAGGACGGGGAGGTCACGATGGCGCGACGTCTGCAGAAATTTCATGAGGAGGTAT
  CAGTCTAGAGTTACCCAGGGCCTCGTGGCCGGAGAAACTGCCCAGCAGATCTGTGAGGAC
  CTCAGGTTGTGTATACCTTCTACAGGTCCCCTCTGAGCCCTCTCACCTTGTCCTGTGGAA
  GAAGCACAGGCTCCTGTCCTCAGATCCCGGGAACCTCAGCAACCTCTGCCGGCTCCTCGC
  TTCCTCGATCCAGAATCCACTCTCCAGTCTCCCTCCCCTGACTCCCTCTGCTGTCCTCCC
  CTCTCACGAGAATAAAGTGTCAAGCANGANAAAAAAAAAAAAAAAAAAAAAAAACTCGAC
  TCTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCCCTGTG
  ACCCCTCCCCAGTGCCTCTCCTGGCCCTGGAAGTTGCCACTCCAGTGCCCACCAGCCTTG
  TCCTAATAAAATTAAGTGCATCATTTTGTCTGACTAGGTGTCCTTCTATATATATGGGTG
  AGGGGGGGGGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006433 unedited
  CGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTCTTGCTTGACA
  CTTTATTCTCGTGAGAGGGGAGGACAGCAAAGGGAGTCAGGGGAGGGAAACTGGAAAGTG
  GATTCTGGATCGAGGAACCGAGGACCCGGCAAAGGTTGCTGAGGTTCCCGGGATCTGAGG
  ACAGGAGCCTGTGCTTCTTCCACAGGACAAGGTGAGAGGGCTCAAAGGGGACCTGTAAAA
  GGTATACACAACCTGAGGTCCTCACAGATCTGCTGGGCAGTTTCTCCGGCCACGAGGCCC
  TGGGTAACTCTAAACTGATACCTCCTCATGAAATTTCTGCAAACGTCGCGCCATCGTGAC
  CTCCCCGTCCTACACACCCGGGTCGCAGCATTGGAAACACTTCTCTGGGTGGGCTTATCC
  ACCATCTTCTTCAGTTTTTGGACTATCGTCAAACAGGTCCTGCAGTCACGGCCCACCTCC
  TGTGTTTTGGTCAACAGGTCACCCTGGGGGCCCTCCTGGGCCAGCCCCGGCCGGTTTTCT
  CCCTCACACCCCCCCGGCGGGCCCCCTTCCCCCCTGTCCCCCCCTCCATTCTTCCCGATC
  TCCTCCCCCTCCCTCCACCCCCGCCTTCCGCCTCCCCCTCCCCCCTCCTTTATTCTCCCT
  CCCCCCTCTCCCCTTCCTCTACCACATTCCCCTTCCCCCCTTTCCCCCCCCCCGCCCCAT
  TCTTTCACCCATTCCTTTTCCCCCTTTTTCCTCCCTGTCCCCCCCCCCCCCCCCACTTCC
  ACCCCCGGTCCTTTCCCAGCACGCGCCTCGCCACCGCCTCCCCCGCGCCCCCCCCCCCTC
  CGCCCCCCCCTCCCCCTCCCCCCCCCACCCCCTCCCCCCCCCCCCCCTCCCCCCTCCTCC
  CCCCTTCCCTTCTTCTTCCCCCCCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006433
• ORF Size: 438 bp
• Insert Size: 640
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006433.2, NP_006424.2
• RefSeq Size: 738
• RefSeq ORF: 438
• Locus ID: 10578
• Domains: SapB_2, SAPB
• Protein Families: Secreted Protein
• Gene Summary: The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' end compared to variant 1. The resulting isoform (2, also known as NKG5) is shorter compared to isoform 1.