Kaiso (ZBTB33) (NM_006777) Human Tagged ORF Clone
CAT#: RC207287L3
- LentiORF®
Lenti ORF clone of Human zinc finger and BTB domain containing 33 (ZBTB33), transcript variant 2, Myc-DDK-tagged
"NM_006777" in other vectors (6)
Product Images
Specifications
Product Data | |
Type | Human Tagged ORF Clone |
Tag | Myc-DDK |
Symbol | ZBTB33 |
Synonyms | ZNF-kaiso; ZNF348 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
E. coli Selection | Chloramphenicol (34 ug/mL) |
Mammalian Cell Selection | Puromycin |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC207287).
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Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
ACCN | NM_006777 |
ORF Size | 2019 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_006777.3, NP_006768.1 |
RefSeq Size | 5225 |
RefSeq ORF | 2019 |
Locus ID | 10009 |
Domains | BTB, zf-C2H2 |
MW | 74.3 kDa |
Gene Summary | This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-α2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC126900 | ZBTB33 (untagged)-Human zinc finger and BTB domain containing 33 (ZBTB33), transcript variant 2 |
USD 310.00 |
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RC207287 | ZBTB33 (Myc-DDK-tagged)-Human zinc finger and BTB domain containing 33 (ZBTB33), transcript variant 2 |
USD 420.00 |
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RG207287 | ZBTB33 (GFP-tagged) - Human zinc finger and BTB domain containing 33 (ZBTB33), transcript variant 2 |
USD 460.00 |
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RC207287L1 | Lenti ORF clone of Human zinc finger and BTB domain containing 33 (ZBTB33), transcript variant 2, Myc-DDK-tagged |
USD 768.00 |
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RC207287L2 | Lenti ORF clone of Human zinc finger and BTB domain containing 33 (ZBTB33), transcript variant 2, mGFP tagged |
USD 620.00 |
|
RC207287L4 | Lenti ORF clone of Human zinc finger and BTB domain containing 33 (ZBTB33), transcript variant 2, mGFP tagged |
USD 620.00 |
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