Kaiso (ZBTB33) (NM_006777) Human Untagged Clone

CAT#: SC126900

ZBTB33 (untagged)-Human zinc finger and BTB domain containing 33 (ZBTB33), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZBTB33
• Synonyms: ZNF-kaiso; ZNF348
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC126900 sequence for NM_006777 edited (data generated by NextGen Sequencing)
  ATGGAGAGTAGAAAACTGATTTCTGCTACAGACATTCAGTACTCTGGCAGTCTGCTGAAC
  TCCTTGAATGAGCAACGTGGCCATGGACTCTTCTGTGATGTTACCGTTATTGTGGAAGAC
  CGAAAATTCCGGGCTCACAAGAATATTCTTTCAGCTTCTAGTACCTACTTCCATCAGCTC
  TTCTCTGTTGCTGGGCAAGTTGTTGAACTGAGCTTTATAAGAGCAGAGATCTTTGCAGAA
  ATTCTCAATTATATCTATAGTTCTAAAATTGTTCGTGTTAGATCAGATTTGCTTGATGAG
  TTAATTAAATCAGGGCAGTTATTAGGAGTGAAATTTATAGCAGAGCTTGGTGTCCCATTG
  TCACAGGTTAAAAGCATCTCAGGTACAGCGCAGGATGGTAATACTGAGCCTTTACCTCCT
  GATTCTGGTGACAAGAACCTTGTAATACAGAAATCAAAAGATGAAGCCCAAGATAATGGG
  GCTACTATAATGCCTATTATAACAGAGTCTTTTTCATTATCTGCCGAAGATTATGAAATG
  AAAAAGATCATTGTTACCGATTCTGATGATGATGATGATGATGTCATTTTTTGCTCCGAG
  ATTCTGCCCACAAAGGAGACTTTGCCGAGTAATAACACAGTGGCACAGGTCCAATCTAAC
  CCAGGCCCTGTTGCTATTTCAGATGTTGCACCTAGTGCTAGCAATAACTCGCCCCCTTTA
  ACAAATATCACACCTACTCAGAAACTTCCTACTCCTGTGAATCAGGCAACTTTGAGCCAA
  ACACAAGGAAGTGAAAAATTGTTGGTATCTTCAGCTCCAACACATCTGACTCCCAATATT
  ATTTTGTTAAATCAGACACCACTTTCTACACCACCAAATGTCAGTTCTTCACTTCCAAAT
  CATATGCCCTCTTCAATCAATTTACTTGTGCAGAATCAGCAGACACCAAACAGTGCTATT
  TTAACAGGAAACAAGGCCAATGAAGAGGAGGAGGAGGAAATAATAGATGATGATGATGAC
  ACTATTAGCTCCAGTCCTGACTCGGCCGTCAGTAATACATCTTTGGTCCCACAGGCTGAT
  ACCTCCCAAAATACCAGTTTTGATGGATCATTAATACAGAAGATGCAGATTCCTACACTT
  CTTCAAGAACCACTTTCCAATTCCTTAAAAATTTCAGATATAATTACTAGAAATACTAAT
  GATCCAGGCGTAGGATCAAAACATCTAATGGAGGGTCAGAAGATCATTACTTTAGATACA
  GCTACTGAAATTGAAGGCTTATCGACTGGTTGCAAGGTTTATGCAAATATCGGTGAAGAT
  ACTTATGATATAGTGATCCCTGTCAAAGATGACCCTGATGAAGGGGAGGCCAGACTTGAG
  AATGAAATACCAAAAACGTCTGGCAGCGAGATGGCAAACAAACGTATGAAAGTAAAACAT
  GATGATCACTATGAGTTAATAGTAGATGGAAGGGTCTATTATATCTGTATTGTATGCAAA
  AGGTCATATGTCTGTCTGACAAGCTTGCGGAGACATTTTAACATTCATTCTTGGGAGAAG
  AAGTATCCGTGCCGTTACTGTGAGAAGGTATTTCCTCTTGCAGAATATCGCACAAAGCAT
  GAAATTCATCACACAGGGGAGCGAAGGTATCAGTGTTTGGCCTGTGGCAAATCTTTCATC
  AACTATCAGTTTATGTCTTCACATATAAAGTCAGTTCATAGTCAAGATCCTTCTGGGGAC
  TCAAAGCTTTATCGTTTACATCCATGCAGGTCTTTACAAATCAGACAATATGCATATCTT
  TCCGATAGATCAAGCACTATTCCTGCAATGAAGGATGATGGTATTGGGTATAAGGTTGAC
  ACTGGAAAAGAACCTCCAGTAGGGACCACTACATCTACTCAGAACAAGCCAATGACCTGG
  GAAGATATTTTTATTCAGCAGGAAAATGATTCAATTTTTAAACAAAATGTAACAGATGGC
  AGTACTGAGTTTGAATTTATAATACCAGAGTCTTACTAA
  
  Clone variation with respect to NM_006777.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006777 unedited
  GAATTCGGCACCAGGCGGCGGCCGCGTCGACGTCGACCCAGACTGGAGCGACGTTTAAAG
  AAGGGGCAGAATCGCTGGGGAGTGCGGCTTCTTCTTGTTGGGGGACTCCCAGCCTTCCGC
  GCGTCCGGAGGAGGAGAAGCGGCGGCGCCGGGAAGCAGGCATGGAGAGTANAAAACTGAT
  TTCTGCTACAGACATTCAGTACTCTGGCAGTCTGCTGAACTCCTTGAATGAGCAACGTGG
  CCATGGACTCTTCTGTGATGTTACCGCTATTGTGGAAGACCGAAAATTCCGGGCTCACAA
  GAATATTCTTTCAGCTTCTAGTACCTACTTCCATCAGCTCTTCTCTGTTGCTGGGCAAGT
  TGTTGAACTGAGCTTTATAAGAGCAGAGATCTTTGCAGAAATTCTCAATTATATCTATAG
  TTCTAAAATTGTTCGTGTTAGATCACATTTGCTTGATGAGTTAATTAAATCACGGCAGTT
  ATTACGAGTGAAATTTATACCAGAGCTTGGTGTCCCATTGGCACAGGTTAAAAGCATTTT
  AGGTCCAGCGCAGGATGGTAATACTGAGCCTTTACCCTCTGATCCTGGTGACAAGAACCT
  TGTCACCCCAAATTAAAACATGAACCCCCAAATAACGGGGGCTCCTATAATGCCCTATAC
  ACCACAGTTTTTCTCCTTACCTGGCCAACATCATGAAATCGAACACCCCACTTGTCCCCC
  CCTCCTACGATCATTACGAAGATTGCCCTTTCTCCGCCCCCACATCTTCACCACC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006777 unedited
  CCCCCTTGAGTNTGACCGGCGAGCCGCATTTACGACCGGGTTTTTTCTTTTTTTTTTTTT
  TTCAGAAATTAATCATTTTATTTTTGCCACAGAAAGCTCTAAGAACTAATATCAGGCCAT
  GGTTAATGAAAAGTAGAACTTACAGTCTTGACAGGGAAAAATTGTACAAGTGTGAACATT
  ACAGTACTCGGAGGAATGAACAGGGTTTCATATAGTTGACCAGCCAAAAAGCCAGTGCTG
  TTAAGTTAGCATTTAATTTTTTAGAATATGCATGCCTTGACAATACAAAATACCTTGATC
  AGTGTTTACCATTTTTTTATCTTTTTGGCACAATGGGGGAAAAATGCGGCATTATTTCTT
  CATAGTGGTTGTGTGTGGGGGATCGTTACCACCAAAATCATAATAATCATTTAAGGTATA
  TTTTAAAGTTAGTCTCGCAGGATTGTTATGGCATTTTTAAATTTCTGTAGTTTAAGCATT
  TTCATTTTGCCATATCTTTTACCAAATTACTATTTCCAGTAGTTCCTATCCAGACCCTTT
  ACCGGTAATTTAGCATAGGAGCAAATTTGAAGCTACCTTCCCACAACAAACGGAAGTTTA
  ATTCGCCGTAGCTTACGCATCCCATAAAAACACACTTATGGCAATTTTAAACAGTTCTCT
  TGCTACAGAATTTCTCATTCCATACATACCCTCTAATGGAGGACTTTTTGCCCCAACAGA
  CCCCTTCCTCATAAAACTTCTACCTTTGCCCTCTGCAACCTTACACCACCAACTTTAGCC
  CCCTTACCTCATGGCCTTCCCTGGAGGTCCCCTGTTCAACCCACTATCTCTTACTCCAGT
  CACTAAAATCATCTCCCCCTCTCAATCCACCTTCTTTTTCTTCACCCCTTTTTCCTCCTC
  TAATCCCCCCTTATAATACTCCTCTATCTCTATTCCCATCTCACC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006777
• ORF Size: 2019 bp
• Insert Size: 4840
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006777.3, NP_006768.1
• RefSeq Size: 5225
• RefSeq ORF: 2019
• Locus ID: 10009
• Domains: BTB, zf-C2H2
• Gene Summary: This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-α2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010]
  Transcript Variant: This variant (2) lacks an exon in the 5' UTR, as compared to variant 1.