Sec8 (EXOC4) (NM_021807) Human Tagged ORF Clone

CAT#: RC209487L4

Lenti ORF clone of Human exocyst complex component 4 (EXOC4), transcript variant 1, mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: EXOC4
• Synonyms: SEC8; SEC8L1; Sec8p
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209487).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_021807
• ORF Size: 2922 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_021807.3, NP_068579.2, NP_068579.3
• RefSeq Size: 4203
• RefSeq ORF: 2925
• Locus ID: 60412
• Domains: Sec8_exocyst
• Protein Pathways: Tight junction
• MW: 110.5 kDa
• Gene Summary: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]