Sec8 (EXOC4) (NM_021807) Human Untagged Clone

CAT#: SC323875

EXOC4 (untagged)-Human exocyst complex component 4 (EXOC4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EXOC4
• Synonyms: SEC8; SEC8L1; Sec8p
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_021807.3 CCCGCGTCCAAGATGGCGGCAGAAGCAGCTGGTGGGAAATACAGAAGCACAGTCAGCAAA
  AGCAAAGACCCCTCGGGGCTGCTCATCTCTGTGATCAGGACTCTGTCTACTAGTGACGAT
  GTCGAAGACAGGGAAAATGAAAAGGGTCGCCTTGAAGAAGCCTACGAGAAATGTGACCGT
  GACCTGGATGAATTGATTGTACAGCACTACACAGAATTGACGACAGCCATTCGCACATAC
  CAGAGCATCACAGAGCGCATCACTAACTCCCGAAATAAAATAAAGCAGGTAAAAGAGAAC
  CTGCTTTCATGCAAGATGCTGCTGCACTGCAAACGGGATGAGCTTCGGAAACTGTGGATT
  GAAGGAATTGAGCATAAGCATGTCCTGAACTTGTTGGATGAAATTGAGAATATCAAGCAA
  GTGCCTCAAAAGCTGGAACAGTGCATGGCCAGCAAGCACTATCTCAGTGCCACTGACATG
  TTGGTGTCAGCAGTTGAGTCTTTGGAGGGCCCCCTGCTCCAGGTGGAAGGACTGAGTGAC
  CTTCGACTAGAGCTTCACAGCAAGAAGATGAACCTTCACTTGGTTCTCATAGATGAACTA
  CACCGGCACCTGTACATCAAATCGACTAGCCGAGTTGTGCAGCGTAACAAGGAAAAAGGG
  AAAATCAGCTCCCTCGTGAAAGATGCTTCTGTTCCTCTGATTGATGTTACAAACCTCCCT
  ACTCCTCGAAAATTCCTTGATACCTCTCACTATTCTACTGCTGGAAGCTCAAGTGTGAGG
  GAGATAAATCTGCAGGACATCAAGGAAGATTTAGAATTGGATCCAGAGGAAAACAGCACC
  CTGTTTATGGGTATCCTCATTAAGGGCTTGGCGAAACTGAAGAAGATCCCAGAAACAGTT
  AAGGCAATCATAGAGCGCTTGGAGCAGGAGTTGAAGCAAATTGTGAAGAGGTCTACAACC
  CAGGTGGCAGACAGTGGCTATCAGCGGGGGGAGAACGTTACTGTGGAGAACCAACCAAGG
  TTGCTTCTAGAACTGCTGGAGTTACTGTTTGACAAGTTTAATGCTGTAGCCGCTGCACAC
  TCTGTGGTCCTGGGATACCTGCAGGACACTGTAGTGACTCCACTGACTCAGCAGGAAGAT
  ATCAAACTGTATGATATGGCAGATGTATGGGTGAAGATCCAAGATGTTCTACAGATGCTA
  TTAACTGAGTACTTGGATATGAAAAATACTCGTACGGCCTCTGAACCATCAGCTCAACTA
  AGCTATGCCAGCACTGGACGAGAGTTTGCAGCCTTTTTTGCCAAGAAGAAACCTCAAAGG
  CCAAAAAATTCTCTTTTCAAGTTCGAATCGTCCTCCCATGCCATCAGTATGAGCGCCTAT
  CTGCGAGAACAGAGAAGGGAGCTCTATAGTCGGAGTGGAGAACTGCAAGGGGGTCCTGAT
  GACAACTTACTTGAAGGTGGAGGAACAAAATTTGTCTGCAAACCTGGAGCCAGAAACATT
  ACCGTCATATTCCACCCATTACTAAGATTTATTCAGGAGATTGAGCATGCTCTGGGTCTT
  GGCCCAGCCAAACAGTGTCCTCTTCGAGAGTTTCTCACCGTGTACATCAAAAACATCTTT
  CTCAATCAAGTCTTGGCTGAGATCAACAAGGAGATTGAAGGAGTCACTAAAACATCTGAC
  CCTTTGAAGATTCTGGCCAACGCAGACACCATGAAGGTGCTGGGAGTGCAGCGGCCTCTC
  CTACAGAGCACAATCATTGTGGAGAAGACAGTTCAAGACCTCCTGAACCTGATGCATGAC
  TTGAGTGCATATTCAGATCAATTCCTCAACATGGTGTGCGTGAAGCTCCAGGAGTACAAG
  GACACCTGCACTGCAGCTTACAGGGGTATTGTCCAGTCAGAAGAAAAACTTGTCATCAGT
  GCATCCTGGGCAAAAGATGATGATATCAGCAGACTCTTGAAATCTCTACCAAACTGGATG
  AATATGGCTCAACCCAAACAGCTGAGGCCAAAAAGAGAGGAGGAAGAAGATTTCATAAGG
  GCAGCTTTTGGCAAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATAAATTAATCCCT
  CCACAAGACATCCTTCGTGACGTCAGTGACCTCAAAGCCTTGGCCAACATGCATGAAAGC
  CTGGAATGGTTGGCAAGTCGAACAAAGTCAGCTTTCTCCAATCTTTCTACATCCCAGATG
  CTTTCTCCTGCTCAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATC
  ATGCAGACTCTCAGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTT
  GTCTTACATCTGGAAGTGAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGAG
  GGGAACTATGCCATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAG
  CTCAACAAAGATATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAG
  TTCCAGTATATCTTCGAAGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGTGCC
  CAGTACTTCAGGCGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTT
  CTTCAGCAGAATTTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGG
  CAGTACTACGAGATGCTTTACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCAG
  GGTGTGAAGTACACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAA
  ACTGGGGTGGGGGAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATC
  TGCGAGCAGGCTGCCATCAAGCAAGCCACCAAGGACAAGAAGATAACTACCGTTTAGCAG
  GGCGTACTGCGGTTGGTGACGGGGGTCCCCTCAGTCACACTCACTTTTTTCCTTGGTATG
  TTATTGAGTATATTCTGAGCTTAGTTTTCTCTACAGTGATACTTTAGTGGAGAGGAGGTG
  TAAGGATTCTTTCTCTCTGGTTTTGGCTTTTCATATAAATGCTAAAGGAAGGCGACAGTA
  CAGAGTGTTTTGGTTGAACAACTACTTTAATGCAGTCAAATCTAACGGGACTAGGGTGGG
  ATAGGGAGGAAGGTGGTATCAAATTGTTGGACTCTGAAAAACAAGTGGATGGATTACTAA
  TATTTGATTTATTACTCAATATATATATAATTCCAGCCTTGGAAAGTAGGAAAGTAGGCT
  GCTACCTAACTTTTAGTCCCTTCCAAAACCATTTAGTAGGGTTCTATTACATAAACAGTA
  GGGTTTTTCCTCTCCTGACCTTATCCGTTTACAGTTCAATGAAATAAGTGTATGTGCATT
  GCTGTCTGTCTCTATTGCCAAAATCAAATAAATGGCTTCTCAGCTGCTGTTTACAACAAA
  CTTCCCTAACCAAAACAGAACCTCTAATTTAGGGCTAGGAATAGAAGTCTTTTGATCCCA
  GTCCGTGGGACAGTTTTGTATGCTGTATCTTGTACACAGGTTGTAGGTTGGTTTATTGCC
  ATTTTGTTTTATTTCTGCTATATAAAAACCAAGAGCCAGACAATTAGACAACTATGGAGG
  AATGAAAGGCAATTCAAACATCTGCTTGATTCCCGCCCCGCCACCCCTAATTTCTGAGAG
  AATAATGGTTAGAGAACATTGCATCTCACTTGAAACATCCTTTGGGGGTAAATGATTCTT
  AGGTGCTCACTTGGTCTGAGCTCAGCTGAATGCAGGGAAGATGGGACAGAGTGACATTTC
  TCCTCTGTGCGGCCTCCAGCTGAGCCTGTCTCTGAATTGTTCCCTCCCCCGCAATGTGGG
  CACTTACCATGTTCCTGGCACACTGGACCTCACCATGTCCCCCGGTCACCAGTCCTCTTG
  CTGCCCATGGTTCATAGGTCATAGAAGGCAGCAATGCACTGACTGGGCCACATCTTGAAA
  ACTCGTGGAAAGGGAAAGGGGAGGAGATGGGACTTTGACCACACACAGTGATGCCTCACA
  CCCTGAAGGTGGGGGATTTTGTACCTGTTTGTACAACTTTGGTCTTGATGGGAAAAATGG
  AGAATTAAAAAGTGTTTTGAGAAGCTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021807.3 unedited
  TACTACTTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTC
  CGGAATTCCCGGGATCCCGCGTCCAAGATGGCGGCAGAAGCAGCTGGTGGGAAATACAGA
  AGCACAGTCAGCAAAAGCAAAGACCCCTCGGGGCTGCTCATCTCTGTGATCAGGACTCTG
  TCTACTAGTGACGATGTCGAAGACAGGGAAAATGAAAAGGGTCGCCTTGAAGAAGCCTAC
  GAGAAATGTGACCGTGACCTGGATGAATTGATTGTACAGCACTACACAGAATTGACGACA
  GCCATTCGCACATACCAGAGCATCACAGAGCGCATCACTAACTCCCGAAATAAAATAAAG
  CAGGTAAAAGAGAACCTGCTTTCATGCAAGATGCTGCTGCACTGCAAACGGGATGAGCTT
  CGGAAACTGTGGATTGAAGGAATTGAGCATAAGCATGTCCTGAACTTGTTGGATGAAATT
  GAGAATATCAAGCAAGTGCCTCAAAAGCTGGAACAGTGCATGGCCAGCAAGCACTATCTC
  AGTGCCACTGACATGTTGGTGTCAGCAGTTGAGTCTTTGGAGGGCCCCCTGCTCCAGGTG
  GAAGGACTGAGTGACCTTCGACTAGAGCTTCACAGCAAGAAGATGAACCTTCACTTGGTT
  CTCATAGATGAACTACACCGGCACCTGTACATCAAATCGACTAGCCGAGTTGTGCAGCGT
  AACAAGGAAAAAGGGAAAATCAGCTCCCTCGTGAAAGATGCTTCTGTTCCTCTGATTGAT
  GTTACAAACCTTCCCTACTCCTCGAAATTCCTTGATACCTCTCACTATTCTACTGCTGAG
  CTCAGTGGTGAGGGAGATAAATCTGCAGGACATCAAGAGATTAGATGATCGAGGAAACAG
  CACCCTGTTATGGGTATCCTCATTAGGGCTTGGCGAACCTGAAGAAGATCCAAAACACG
• Restriction Sites: ECoRI-NOT
• ACCN: NM_021807
• ORF Size: 2925 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_021807.3, NP_068579.3
• RefSeq Size: 4203
• RefSeq ORF: 2925
• Locus ID: 60412
• Domains: Sec8_exocyst
• Protein Pathways: Tight junction
• Gene Summary: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).