Sec8 (EXOC4) (NM_021807) Human Untagged Clone

CAT#: SC102359

EXOC4 (untagged)-Human exocyst complex component 4 (EXOC4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EXOC4
• Synonyms: SEC8; SEC8L1; Sec8p
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC102359 sequence for NM_021807 edited (data generated by NextGen Sequencing)
  ATGGCGGCAGAAGCAGCTGGTGGGAAATACAGAAGCACAGTCAGCAAAAGCAAAGACCCC
  TCGGGGCTGCTCATCTCTGTGATCAGGACTCTGTCTACTAGTGACGATGTCGAAGACAGG
  GAAAATGAAAAGGGTCGCCTTGAAGAAGCCTACGAGAAATGTGACCGTGACCTGGATGAA
  TTGATTGTACAGCACTACACAGAATTGACGACAGCCATTCGCACATACCAGAGCATCACA
  GAGCGCATCACTAACTCCCGAAATAAAATAAAGCAGGTAAAAGAGAACCTGCTTTCATGC
  AAGATGCTGCTGCACTGCAAACGGGATGAGCTTCGGAAACTGTGGATTGAAGGAATTGAG
  CATAAGCATGTCCTGAACTTGTTGGATGAAATTGAGAATATCAAGCAAGTGCCTCAAAAG
  CTGGAACAGTGCATGGCCAGCAAGCACTATCTCAGTGCCACTGACATGTTGGTGTCAGCA
  GTTGAGTCTTTGGAGGGCCCCCTGCTCCAGGTGGAAGGACTGAGTGACCTTCGACTAGAG
  CTTCACAGCAAGAAGATGAACCTTCACTTGGTTCTCATAGATGAACTACACCGGCACCTG
  TACATCAAATCGACTAGCCGAGTTGTGCAGCGTAACAAGGAAAAAGGGAAAATCAGCTCC
  CTCGTGAAAGATGCTTCTGTTCCTCTGATTGATGTTACAAACCTCCCTACTCCTCGAAAA
  TTCCTTGATACCTCTCACTATTCTACTGCTGGAAGCTCAAGTGTGAGGGAGATAAATCTG
  CAGGACATCAAGGAAGATTTAGAATTGGATCCAGAGGAAAACAGCACCCTGTTTATGGGT
  ATCCTCATTAAGGGCTTGGCGAAACTGAAGAAGATCCCAGAAACAGTTAAGGCAATCATA
  GAGCGCTTGGAGCAGGAGTTGAAGCAAATTGTGAAGAGGTCTACAACCCAGGTGGCAGAC
  AGTGGCTATCAGCGGGGGGAGAACGTTACTGTGGAGAACCAACCAAGGTTGCTTCTAGAA
  CTGCTGGAGTTACTGTTTGACAAGTTTAATGCTGTAGCCGCTGCACACTCTGTGGTCCTG
  GGATACCTGCAGGACACTGTAGTGACTCCACTGACTCAGCAGGAAGATATCAAACTGTAT
  GATATGGCAGATGTATGGGTGAAGATCCAAGATGTTCTACAGATGCTATTAACTGAGTAC
  TTGGATATGAAAAATACTCGTACGGCCTCTGAACCATCAGCTCAACTAAGCTATGCCAGC
  ACTGGACGAGAGTTTGCAGCCTTTTTTGCCAAGAAGAAACCTCAAAGGCCAAAAAATTCT
  CTTTTCAAGTTCGAATCGTCCTCCCATGCCATCAGTATGAGCGCCTATCTGCGAGAACAG
  AGAAGGGAGCTCTATAGTCGGAGTGGAGAACTGCAAGGGGGTCCTGATGACAACTTAATT
  GAAGGTGGAGGAACAAAATTTGTCTGCAAACCTGGAGCCAGAAACATTACCGTCATATTC
  CACCCATTACTAAGATTTATTCAGGAGATTGAGCATGCTCTGGGTCTTGGCCCAGCCAAA
  CAGTGTCCTCTTCGAGAGTTTCTCACCGTGTACATCAAAAACATCTTTCTCAATCAAGTC
  TTGGCTGAGATCAACAAGGAGATTGAAGGAGTCACTAAAACATCTGACCCTTTGAAGATT
  CTGGCCAACGCAGACACCATGAAGGTGCTGGGAGTGCAGCGGCCTCTCCTACAGAGCACA
  ATCATTGTGGAGAAGACAGTTCAAGACCTCCTGAACCTGATGCATGACTTGAGTGCATAT
  TCAGATCAATTCCTCAACATGGTGTGCGTGAAGCTCCAGGAGTACAAGGACACCTGCACT
  GCAGCTTACAGGGGTATTGTCCAGTCAGAAGAAAAACTTGTCATCAGTGCATCCTGGGCA
  AAAGATGATGATATCAGCAGACTCTTGAAATCTCTACCAAACTGGATGAATATGGCTCAA
  CCCAAACAGCTGAGGCCAAAAAGAGAGGAGGAAGAAGATTTCATAAGGGCAGCTTTTGGC
  AAGGAGTCTGAAGTTCTTATTGGGAACCTGGGTGATAAATTAATCCCTCCACAAGACATC
  CTTCGTGACGTCAGTGACCTCAAAGCCTTGGCCAACATGCATGAAAGCCTGGAATGGTTG
  GCAAGTCGAACAAAGTCAGCTTTCTCCAATCTTTCTACATCCCAGATGCTTTCTCCTGCT
  CAAGACAGCCACACGAACACGGATCTCCCCCCAGTGTCAGAGCAGATCATGCAGACTCTC
  AGTGAACTTGCCAAATCGTTCCAGGATATGGCTGACCGCTGCTTGCTTGTCTTACATCTG
  GAAGTGAGGGTTCACTGTTTCCACTATCTTATCCCTCTTGCAAAGGAGGGGAACTATGCC
  ATTGTGGCTAATGTGGAAAGTATGGATTATGACCCCCTGGTGGTCAAGCTCAACAAAGAT
  ATCAGCGCCATTGAAGAGGCCATGAGCGCCAGCCTTCAGCAGCACAAGTTCCAGTATATC
  TTCGAAGGCCTGGGCCACCTGATCTCCTGCATCCTCATTAATGGTGCCCAGTACTTCAGG
  CGCATCAGTGAGTCTGGCATCAAGAAAATGTGTAGGAACATTTTTGTTCTTCAGCAGAAT
  TTGACCAACATCACCATGTCGCGGGAGGCAGACCTGGACTTTGCAAGGCAGTACTACGAG
  ATGCTTTACAACACAGCTGACGAGCTCCTGAACCTGGTGGTGGACCAGGGTGTGAAGTAC
  ACGGAGCTGGAGTACATCCACGCTCTGACCCTGCTGCACCGCAGCCAGACTGGGGTGGGG
  GAACTGACCACCCAGAACACGAGGCTGCAGAGGCTCAAAGAGATCATCTGCGAGCAGGCT
  GCCATCAAGCAAGCCACCAAGGACAAGAAGATAACTACCGTTTAG
  
  Clone variation with respect to NM_021807.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021807 unedited
  ATTATGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCAAGATGGCGG
  CAGAAGCAGCTGGTGGGAAATACAGAAGCACAGTCAGCAAAAGCAAAGACCCCTCGGGGC
  TGCTCATCTCTGTGATCAGGACTCTGTCTACTAGTGACGATGTCGAAGACAGGGAAAATG
  AAAAGGGTCGCCTTGAAGAAGCCTACGAGAAATGTGACCGTGACCTGGATGAATTGATTG
  TACAGCACTACACAGAATTGACGACAGCCATTCGCACATACCAGAGCATCACAGAGCGCA
  TCACTAACTCCCGAAATAAAATAAAGCAGGTAAAAGAGAACCTGCTTTCATGCAAGATGC
  TGCTGCACTGCAAACGGGATGAGCTTCGGAAACTGTGGATTGAAGGAATTGAGCATAAGC
  ATGTCCTGAACTTGTTGGATGAAATTGAGAATATCAAGCAAGTGCCTCAAAAGCTGGAAC
  AGTGCATGGCCAGCAAGCACTATCTCAGTGCCACTGACATGTTGGTGTCAGCAGTTGAGT
  CTTTGGAGGGCCCCCTGCTCCAGGTGGAAGGACTGAGTGACCTTCGACTAGAGCTTCACA
  GCAAGAAGATGAACCTTCACTTGGTTCTCATAGATGAACTACACCGGCACCTGTACATCA
  NATCGACTAGCCGAGTTGTGCAGCGTAACAAGGAAAAGGGANAATCAGCTCCCTCGTGAA
  AGATGCTTCTGTTCCTCTGATTGATGTTACCAACCTCCCTACTNCTCCGAAATNCCTGAT
  ACCTCTCACTATTCTACTGCTGGAAGCTCAAGTGTGAGGGAGATAAATCTTGCAGACATC
  ANGGAAGATTAGAATTGGATCCAGAGAAAACAGCACCCTGTTTATGGGTATTCTTATTAA
  GGGCTGNCGAAACTGAAGAAGACCCAGNAACAGTTAAGCAATCTAAAACGCTGTAGCAGA
  GTTGACAAATGTGAAAGTCTCAACCAGTGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_021807 unedited
  TGGGCACACCCTCGAGTGNNCGAGTTAAAANCCCTTTTTTTTTTTAAGCTNCTCAATCTC
  GTTTTAATTCTTCTTTTTTCCCATCAAGACCAAAGTTGTACAAACAGGTACAAAATCCCC
  CACCTTCAGGGTGTGAGGCATCACTGTGTGTGGTCAAAGTCCCATCTCCTCCCCTTTCCC
  TTTCCACGAGTTTTCAAGATGTGGCCCAGTCTGTGCATTGCTGCCTTCTATGACCTATGA
  ACCATGGGCAGCAAGAGGACTGGTGACCGGGGGACATGGTGAGGTCCAGTGTGCCAGGAA
  CATGGTAAGTGCCCACATTGCGGGGGAGGGAACAATTCAGAGACAGGCTCAGCTGGATGC
  CGCACAGAGGAGAAATGTTACTCTGTCCCATCTTCCCTGCATTCAGCTGAGCTTCAGACC
  AAGTGAGCACCTAACACTCATTTACCCCCAAAGGATGTTCCAAGTGAGATGCAATGCTCT
  CTAACCATTATCCTCTAAGAAATTACGGGCGGTGGCGCGGCGATCAAGCCCATGGTTTGA
  ATTGCCTTTTATTCCTCCATACTCGCCTAATTGTCTGGCTCTTGGTTTTTTCTCCCCCAA
  CACACTTCCGGCATTAAACCCCCCACAACTGTGTTCACACCCCGCACCCAAATTGTCCAC
  GTACCGCCACCCAAGACTCCCCTCCTTTCCCTAACCACACGCCCGTTTTGGTCCGCGTAA
  CCCGCGCAAAACCCCCCGGCCACCCCCTTTTCGATTTCGGTTTAAACCCGTACAGCCCCC
  CATAACCCCCTCCTCTGAATGTCACCCATTTGGTCGACCCCGAAAACCCCCCGGTTCCTC
  AAACCCCCCTACGGCCCCGCAGGGCTCCACTCTCTCCACCTCCCCTTATTTCCCAGTCGC
  ATTTCTTCCCCGCGATATCCCCTTTTTCTTTTCCCGTTTCCCCCCCAAATTCCCCCACTT
  TCCTTCCATCCCCTCCCCT
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_021807
• ORF Size: 4203 bp
• Insert Size: 4310
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_021807.2, NP_068579.2
• RefSeq Size: 4215
• RefSeq ORF: 4203
• Locus ID: 60412
• Domains: Sec8_exocyst
• Protein Pathways: Tight junction
• Gene Summary: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).