AFF4 (NM_014423) Human Tagged ORF Clone

CAT#: RC217692L4

Lenti ORF clone of Human AF4/FMR2 family, member 4 (AFF4), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: AFF4
• Synonyms: AF5Q31; CHOPS; MCEF
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC217692).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_014423
• ORF Size: 3489 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_014423.2, NP_055238.1
• RefSeq Size: 9528
• RefSeq ORF: 3492
• Locus ID: 27125
• Domains: AF-4
• Protein Families: Transcription Factors
• MW: 127.3 kDa
• Gene Summary: The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). [provided by RefSeq, Oct 2011]