AFF4 (NM_014423) Human Untagged Clone

CAT#: SC108598

AFF4 (untagged)-Human AF4/FMR2 family, member 4 (AFF4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AFF4
• Synonyms: AF5Q31; CHOPS; MCEF
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108598 sequence for NM_014423 edited (data generated by NextGen Sequencing)
  ATGAACCGTGAAGACCGGAATGTGCTGCGTATGAAAGAACGGGAAAGGCGGAATCAGGAA
  ATTCAGCAGGGCGAAGACGCCTTCCCACCTAGCTCTCCTCTCTTTGCAGAGCCATACAAA
  GTTACTAGCAAAGAAGATAAGTTATCAAGTCGTATTCAGAGTATGCTTGGAAACTACGAT
  GAAATGAAGGATTTCATAGGAGACAGATCTATACCAAAGCTTGTTGCAATTCCCAAGCCT
  ACAGTACCACCATCAGCAGATGAAAAATCTAACCCAAATTTCTTTGAACAGAGACATGGA
  GGCTCTCATCAGAGTAGCAAATGGACTCCAGTAGGACCCGCACCCAGCACTTCTCAGTCT
  CAGAAACGGTCCTCAGGCTTACAGAGTGGACATAGTAGCCAGCGGACCAGCGCAGGTAGC
  AGTAGTGGCACTAACAGTAGTGGTCAGAGGCACGACCGTGAGTCATATAACAATAGTGGG
  AGCAGTAGCCGGAAAAAAGGCCAGCATGGATCAGAACACTCCAAATCACGTTCTTCCAGC
  CCTGGAAAACCCCAGGCTGTTTCTTCATTAAACTCTAGTCATTCCAGGTCTCATGGGAAT
  GATCACCATAGCAAGGAACATCAACGCTCCAAATCACCTCGGGACCCTGATGCAAACTGG
  GATTCTCCTTCCCGTGTACCTTTTTCAAGTGGGCAGCACTCAACTCAATCTTTCCCACCC
  TCATTGATGTCAAAGTCCAATTCAATGTTACAGAAACCCACTGCCTATGTGCGGCCCATG
  GACGGACAGGAGTCCATGGAACCAAAGCTGTCCTCTGAGCACTACAGCAGCCAATCCCAT
  GGCAACAGCATGACTGAGCTGAAGCCCAGCAGCAAAGCACATCTCACCAAGCTGAAAATA
  CCTTCCCAACCACTGGATGCATCAGCTTCTGGTGATGTGAGCTGTGTGGATGAAATCCTA
  AAAGAGATGACGCATTCATGGCCTCCCCCTCTAACGGCTATTCATACACCATGCAAAACA
  GAACCTTCCAAATTTCCTTTTCCAACTAAGGAGTCTCAGCAGTCCAATTTTGGCACTGGA
  GAACAAAAAAGATATAATCCTTCTAAAACTTCAAATGGGCACCAGTCTAAATCTATGTTA
  AAAGATGACTTAAAACTAAGCAGCAGTGAAGACAGTGATGGGGAACAGGATTGTGATAAG
  ACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCACACCATAATAGTGAAGGA
  GCAGATAACTCCAGGGATGATTCTAGTAGCCACAGTGGATCTGAAAGCAGCTCTGGATCT
  GACTCAGAGAGTGAAAGTAGTTCCAGTGACAGTGAGGCAAATGAGCCATCCCAGAGTGCA
  TCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTTGATAATTGGCTGAATAAA
  GTGAACCCACATAAAGTGTCACCCGCCTCTTCAGTGGACAGTAACATCCCATCATCTCAA
  GGCTACAAAAAGGAAGGCCGAGAGCAGGGCACTGGGAATAGCTACACTGATACAAGTGGA
  CCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAAACCATCCAAAAGGGATCA
  GAAAGTGGGCGTGGGAGGCAGAAATCTCCTGCACAGAGTGACAGCACAACACAGAGAAGA
  ACTGTAGGCAAAAAACAACCCAAAAAGGCTGAGAAGGCAGCTGCTGAAGAGCCTCGTGGA
  GGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGCAGCATGCCCTCCAGCAGA
  CACAAAGCAGCCACCAAAGGCTCAAGGAAACCCAATATAAAGAAGGAGTCTAAGTCTTCC
  CCTCGACCTACAGCAGAGAAAAAGAAATATAAGTCAACAAGTAAATCTTCCCAGAAATCA
  AGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGATGAAAGTGAGAGCCTTCCT
  CCTTCCTCACAAACTCCTAAGTACCCCGAGAGCAATAGGACTCCTGTTAAACCCTCCTCA
  GTGGAGGAAGAAGATAGCTTTTTTCGGCAACGAATGTTCTCTCCTATGGAAGAGAAGGAA
  CTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTTATTGTGAAGATTGACCTG
  AATCTTTTGACTAGAATACCAGGAAAGCCTTACAAAGAAACAGAGCCGCCCAAGGGGGAA
  AAGAAAAATGTGCCAGAAAAGCACACGAGAGAGGCTCAGAAACAAGCCTCAGAAAAAGTT
  TCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAACCGAGCCAGTGAGAGCAAG
  AAACCCAAAACGGAGGACAAGAATTCAGCAGGCCATAAGCCATCCAGCAACAGAGAGTCA
  TCTAAGCAGAGTGCTGCAAAAGAAAAGGATTTGTTGCCTTCTCCCGCTGGGCCTGTTCCT
  TCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACTATTAGTCAGTCTTCTTCC
  TTAAAGTCAAGCAGTAACAGCAACAAGGAGACGAGTGGCAGCAGCAAAAACAGTTCCTCC
  ACATCAAAGCAGAAGAAGACCGAAGGGAAGACTTCCAGTAGCTCCAAGGAGGTTAAGGAA
  AAGGCTCCAAGTAGCTCCTCTAACTGTCCTCCATCTGCACCAACTCTTGATTCTTCTAAG
  CCTCGGAGAACAAAGCTTGTCTTTGATGACAGAAATTATTCAGCAGACCATTATTTACAA
  GAAGCAAAAAAGCTAAAGCACAATGCAGATGCATTGTCTGATAGGTTTGAGAAAGCTGTA
  TACTATCTTGATGCTGTGGTATCTTTCATTGAATGTGGGAATGCATTAGAGAAGAATGCT
  CAGGAATCCAAATCCCCATTCCCTATGTATTCAGAGACGGTGGATCTCATCAAATACACT
  ATGAAGCTAAAGAATTACTTGGCACCAGATGCTACAGCTGCAGATAAACGACTCACAGTA
  CTTTGCCTGCGATGCGAGTCTTTGCTGTACCTGAGGCTGTTCAAACTGAAGAAGGAAAAT
  GCTCTGAAGTACTCAAAGACACTGACAGAGCACCTGAAGAATTCTTATAATAATTCTCAA
  GCACCATCGCCTGGCTTGGGAAGCAAAGCTGTGGGGATGCCTTCCCCTGTTTCTCCAAAG
  CTGTCACCAGGCAATTCAGGAAATTATTCATCTGGGGCCAGTAGTGCTTCTGCAAGTGGT
  TCTTCAGTGACCATTCCACAGAAGATCCACCAGATGGCAGCCAGCTATGTTCAGGTCACA
  TCCAACTTCCTCTATGCCACCGAAATTTGGGACCAAGCTGAACAGCTTTCCAAAGAGCAA
  AAAGAATTCTTTGCTGAACTGGATAAAGTAATGGGCCCTCTCATCTTTAATGCAAGCATC
  ATGACAGATCTAGTTCGTTATACCCGGCAGGGACTGCACTGGCTTCGCCAGGATGCCAAG
  TTGATATCTTGA
  
  Clone variation with respect to NM_014423.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014423 unedited
  CCAGCGAATTCGGCACGAGCTGGAGGGAATCTAGAGCATCAGCAAAGCTGAGGTCAAACT
  ACCGTAAGGATGGACACCAAGGAAGCTGTGTTTGGGACAAAAAGAAATCAAGATAAGCAA
  CATGAACCGTGAAGACCGGAATGTGCTGCGTATGAAAGAACGGGAAAGGCGGAATCAGGA
  AATTCAGCAGGGGCGAAGACTTTCTTCCCACGTAGCTCTCCTCTCTTTGCAGAGCCATAC
  AAAGTTACTAGCAAAGAAGATAAGTTATCAAGTCGTATTCAGAGTATGCTTGGAAACTAC
  GATGAAATGAAGGATTTCATAGGAGACAGATCTATACCAAAGCTTGTTGCAATTCCCAAG
  CCTACAGTACCACCATCAGCAGATGAAAAATCTAACCCAAATTTCTTTGAACAGAGACAT
  GGAGGCTCTCATCAGAGTAGCAAATGGACTCCAGTAGGACCCGCACCCAGCACTTCTCAG
  TCTCAGAAACGGTCCTCAGGCTTACAGAGTGGACATAGTAGCCAGCGGACCAGCGCANGT
  AGCAGTAGTGGCACTAACAGTAGTGGTCAGAGGCACGACCCGGAGTCATATAACAATAGT
  GGGAGCAGTAGCCCGGAAAAAGGCCAGCATGGATCAAAACACTCCAAATCACGTTCTTCC
  AGCCCTGGAAAACCCCAGGCTGTTTCTTATTAAACTCTAGTCATCCCAGGCTCATGGGAA
  TGACACCCTTGCAGGGACATCACCGCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_014423 unedited
  ACCCGGCAGGGACTGCACTGGCTTCGCCAGGATGCCAAGTTGATATCTTGAACTGAACAC
  ATTCTCGTTGCCTCTGATTTTCTCCACAACACTGTGTCACATCACGAAGGAAAACTGCCA
  TAACATACCACCTAGTCGACACTAAGAATGAGGAATAGTTTTCTCCTCGTTGGTTCATGT
  GTTGTTGTTTTTGATAATCCAAAGCGATCATGTCAGTTGGCCCTTTAATATTTCCAATGT
  GAAAGATTATTTAAATGCTTTTAAATCTGCAGCACATTGATAAGATGGTTTCCGTGAGCT
  ATGATAANATTGAAATTCCAGTTGCAATTCATAACTAATGAATTGAAATTTTATTTATTT
  TAATTTTTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014423
• ORF Size: 3492 bp
• Insert Size: 4700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_014423.2, NP_055238.1
• RefSeq Size: 9528
• RefSeq ORF: 3492
• Locus ID: 27125
• Domains: AF-4
• Protein Families: Transcription Factors
• Gene Summary: The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). [provided by RefSeq, Oct 2011]