ASPP1 (PPP1R13B) (NM_015316) Human Tagged ORF Clone

CAT#: RC221172L4

Lenti ORF clone of Human protein phosphatase 1, regulatory (inhibitor) subunit 13B (PPP1R13B), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: PPP1R13B
• Synonyms: ASPP1; p53BP2-like; p85
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC221172).
• Restriction Sites: SgfI-RsrII Cloning Scheme for this gene
• ACCN: NM_015316
• ORF Size: 3270 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_015316.1, NP_056131.1, NP_056131.2
• RefSeq Size: 4834
• RefSeq ORF: 3273
• Locus ID: 23368
• Domains: SH3, ANK
• Protein Families: Druggable Genome
• MW: 119.4 kDa
• Gene Summary: This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008]