Thrombospondin 2 (THBS2) (NM_003247) Human Tagged ORF Clone

CAT#: RC223225L4

Lenti ORF clone of Human thrombospondin 2 (THBS2), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: THBS2
• Synonyms: TSP2
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC223225).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_003247
• ORF Size: 3516 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_003247.2, NP_003238.2
• RefSeq Size: 5826
• RefSeq ORF: 3519
• Locus ID: 7058
• Domains: tsp_1, VWC, EGF_CA, TSPN, tsp_3, EGF, EGF
• Protein Families: Druggable Genome
• Protein Pathways: ECM-receptor interaction, Focal adhesion, TGF-beta signaling pathway
• MW: 129.99 kDa
• Gene Summary: The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration. [provided by RefSeq, Jul 2008]