Thrombospondin 2 (THBS2) (NM_003247) Human Untagged Clone

CAT#: SC127167

THBS2 (untagged)-Human thrombospondin 2 (THBS2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: THBS2
• Synonyms: TSP2
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_003247 edited
  GAATTCGGCACGAGGGTCATTCCTTCGAAGGAATGAATTAAACGTGCTTCCTCGTGTGTC
  TGATTGACAGCCCTGCACAGGAGAAGCGGCATATAAAGCCGCGCTGCCCGGGAGCCGCTC
  GGCCACGTCCACCGGAGCATCCTGCACTGCAGGGCCGGTCTCTCGCTCCAGCAGAGCCTG
  CGCCTTTCTGACTCGGTCCGGAACACTGAAACCAGTCATCACTGCATCTTTTTGGCAAAC
  CAGGAGCTCAGCTGCAGGAGGCAGGATGGTCTGGAGGCTGGTCCTGCTGGCTCTGTGGGT
  GTGGCCCAGCACGCAAGCTGGTCACCAGGACAAAGACACGACCTTCGACCTTTTCAGTAT
  CAGCAACATCAACCGCAAGACCATTGGCGCCAAGCAGTTCCGCGGGCCCGACCCCGGCGT
  GCCGGCTTACCGCTTCGTGCGCTTTGACTACATCCCACCGGTGAACGCAGATGACCTCAG
  CAAGATCACCAAGATCATGCGGCAGAAGGAGGGCTTCTTCCTCACGGCCCAGCTCAAGCA
  GGACGGCAAGTCCAGGGGCACGCTGTTGGCTCTGGAGGGCCCCGGTCTCTCCCAGAGGCA
  GTTCGAGATCGTCTCCAACGGCCCCGCGGACACGCTGGATCTCACCTACTGGATTGACGG
  CACCCGGCATGTGGTCTCCCTGGAGGACGTCGGCCTGGCTGACTCGCAGTGGAAGAACGT
  CACCGTGCAGGTGGCTGGCGAGACCTACAGCTTGCACGTGGGCTGCGACCTCATAGACAG
  CTTCGCTCTGGACGAGCCCTTCTACGAGCACCTGCAGGCGGAAAAGAGCCGGATGTACGT
  GGCCAAAGGCTCTGCCAGAGAGAGTCACTTCAGGGGTTTGCTTCAGAACGTCCACCTAGT
  GTTTGAAAACTCTGTGGAAGATATTCTAAGCAAGAAGGGTTGCCAGCAAGGCCAGGGAGC
  TGAGATCAACGCCATCAGTGAGAACACAGAGACGCTGCGCCTGGGTCCGCATGTCACCAC
  CGAGTACGTGGGCCCCAGCTCGGAGAGGAGGCCCGAGGTGTGCGAACGCTCGTGCGAGGA
  GCTGGGAAACATGGTCCAGGAGCTCTCGGGGCTCCACGTCCTCGTGAACCAGCTCAGCGA
  GAACCTCAAGAGAGTGTCGAATGATAACCAGTTTCTCTGGGAGCTCATTGGTGGCCCTCC
  TAAGACAAGGAACATGTCAGCTTGCTGGCAGGATGGCCGGTTCTTTGCGGAAAATGAAAC
  GTGGGTGGTGGACAGCTGCACCACGTGTACCTGCAAGAAATTTAAAACCATTTGCCACCA
  AATCACCTGCCCGCCTGCAACCTGCGCCAGTCCATCCTTTGTGGAAGGCGAATGCTGCCC
  TTCCTGCCTCCACTCGGTGGACGGTGAGGAGGGCTGGTCTCCGTGGGCAGAGTGGACCCA
  GTGCTCCGTGACGTGTGGCTCTGGGACCCAGCAGAGAGGCCGGTCCTGTGACGTCACCAG
  CAACACCTGCTTGGGGCCCTCCATCCAGACACGGGCTTGCAGTCTGAGCAAGTGTGACAC
  CCGCATCCGGCAGGACGGCGGCTGGAGCCACTGGTCACCTTGGTCTTCATGCTCTGTGAC
  CTGTGGAGTTGGCAATATCACACGCATCCGTCTCTGCAACTCCCCAGTGCCCCAGATGGG
  GGGCAAGAATTGCAAAGGGAGTGGCCGGGAGACCAAAGCCTGCCAGGGCGCCCCATGCCC
  AATCGATGGCCGCTGGAGCCCCTGGTCCCCGTGGTCGGCCTGCACTGTCACCTGTGCCGG
  TGGGATCCGGGAGCGCACCCGGGTCTGCAACAGCCCTGAGCCTCAGTACGGAGGGAAGGC
  CTGCGTGGGGGATGTGCAGGAGCGTCAGATGTGCAACAAGAGGAGCTGCCCCGTGGATGG
  CTGTTTATCCAACCCCTGCTTCCCGGGAGCCCAGTGCAGCAGCTTCCCCGATGGGTCCTG
  GTCATGCGGCTCCTGCCCTGTGGGCTTCTTGGGCAATGGCACCCACTGTGAGGACCTGGA
  CGAGTGTGCCCTGGTCCCCGACATCTGCTTCTCCACCAGCAAGGTGCCTCGCTGTGTCAA
  CACTCAGCCTGGCTTCCACTGCCTGCCCTGCCCGCCCCGATACAGAGGGAACCAGCCCGT
  CGGGGTCGGCCTGGAAGCAGCCAAGACGGAAAAGCAAGTGTGTGAGCCCGAAAACCCATG
  CAAGGACAAGACACACAACTGCCACAAGCACGCGGAGTGCATCTACCTGGGCCACTTCAG
  CGACCCCATGTACAAGTGCGAGTGCCAGACAGGCTACGCGGGCGACGGGCTCATCTGCGG
  GGAGGACTCGGACCTGGACGGCTGGCCCAACCTCAATCTGGTCTGCGCCACCAACGCCAC
  CTACCACTGCATCAAGGATAACTGCCCCCATCTGCCAAATTCTGGGCAGGAAGACTTTGA
  CAAGGACGGGATTGGCGATGCCTGTGATGATGACGATGACAATGACGGTGTGACCGATGA
  GAAGGACAACTGCCAGCTCCTCTTCAATCCCCGCCAGGCTGACTATGACAAGGATGAGGT
  TGGGGACCGCTGTGACAACTGCCCTTACGTGCACAACCCTGCCCAGATCGACACAGACAA
  CAATGGAGAGGGTGACGCCTGCTCCGTGGACATTGATGGGGACGATGTCTTCAATGAACG
  AGACAATTGTCCCTACGTCTACAACACTGACCAGAGGGACACGGATGGTGACGGTGTGGG
  GGATCACTGTGACAACTGCCCCCTGGTGCACAACCCTGACCAGACCGACGTGGACAATGA
  CCTTGTTGGGGACCAGTGTGACAACAACGAGGACATAGATGACGACGGCCACCAGAACAA
  CCAGGACAACTGCCCCTACATCTCCAACGCCAACCAGGCTGACCATGACAGAGACGGCCA
  GGGCGACGCCTGTGACCCTGATGATGACAACGATGGCGTCCCCGATGACAGGGACAACTG
  CCGGCTTGTGTTCAACCCAGACCAGGAGGACTTGGACGGTGATGGACGGGGTGATATTTG
  TAAAGATGATTTTGACAATGACAACATCCCAGATATTGATGATGTGTGTCCTGAAAACAA
  TGCCATCAGTGAGACAGACTTCAGGAACTTCCAGATGGTCCCCTTGGATCCCAAAGGGAC
  CACCCAAATTGATCCCAACTGGGTCATTCGCCATCAAGGCAAGGAGCTGGTTCAGACAGC
  CAACTCGGACCCCGGCATCGCTGTAGGTTTTGACGAGTTTGGGTCTGTGGACTTCAGTGG
  CACATTCTACGTAAACACTGACCGGGACGACGACTATGCCGGCTTCGTCTTTGGTTACCA
  GTCAAGCAGCCGCTTCTATGTGGTGATGTGGAAGCAGGTGACGCAGACCTACTGGGAGGA
  CCAGCCCACGCGGGCCTATGGCTACTCCGGCGTGTCCCTCAAGGTGGTGAACTCCACCAC
  GGGGACGGGCGAGCACCTGAGGAACGCGCTGTGGCACACGGGGAACACGCCGGGGCAGGT
  GCGAACCTTATGGCACGACCCCAGGAACATTGGCTGGAAGGACTACACGGCCTATAGGTG
  GCACCTGACTCACAGGCCCAAGACTGGCTACATCAGAGTCTTAGTGCATGAAGGAAAACA
  GGTCATGGCAGACTCAGGACCTATCTATGACCAAACCTACGCTGGCGGGCGGCTGGGTCT
  ATTTGTCTTCTCTCAAGAAATGGTCTATTTCTCAGACCTCAAGTACGAATGCAGAGATAT
  TTAAACAAGATTTGCTGCATTTCCGGCAATGCCCTGTGCATGCCATGGTCCCTAGACACC
  TCAGTTCATTGTGGTCCTTGTGGCTTCTCTCTCTAGCAGCACCTCCTGTCCCTTGACCTT
  AACTCTGATGGTTCTTCACCTCCTGCCAGCAACCCCAAACCCAAGTGCCTTCAGAGGATA
  AATATCAATGGAACTCAGAGATGAACATCTAACCCACTAGAGGAAACCAGTTTGGTGATA
  TATGAGACTTTATGTGGAGTGAAAATTGGGCATGCCATTACATTGCTTTTTCTTGTTTGT
  TTAAAAAGAATGACGTTTACATAT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003247 unedited
  TACCCCCGCCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGC
  AGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGCG
  AATTCGGCACGAGGGTCATTCCTTCGAAGGAATGAATTAAACGTGCTTCCTCGTGTGTCT
  GATTGACAGCCCTGCACAGGAGAAGCGGCATATAAAGCCGCGCTGCCCGGGAGCCGCTCG
  GCCACGTCCACCGGAGCATCCTGCACTGCAGGGCCGGTCTCTCGCTCCAGCAGAGCCTGC
  GCCTTTCTGACTCGGTCCGGAACACTGAAACCAGTCATCACTGCATCTTTTTGGCAAACC
  AGGAGCTCAGCTGCAGGAGGCAGGATGGTCTGGAGGCTGGTCCTGCTGGCTCTGTGGGTG
  TGGCCCAGCACGCAAGCTGGTCACCAGGACAAAGACACGACCTTCGACCTTTTCAGTATC
  AGCAACATCAACCGCAAGACCATTGGCGCCAAGCAGTTCCGCGGGCCCGACCCCGGCGTG
  CCGGCTTACCGCTTCGTGCGCTTTGACTACATCCCACCGGTGAACGCAGATGACCTCAGC
  AAGATCACCAAGATCATGCGGCAGAAGGAGGGCTTCTTCCTCACGGCCCAGCTCAAGCAG
  GACGGCAAGTCCAGNGGCACGCTGNTGGCTCTGGGAGGGCCCCGGTCTCTCCCGNAGCAG
  TTTCGAGATCGTCTCCAACGGCCCCCGCGACACGCTGGATCTCACTACTGGATTGACGNA
  CCCGGCATGTGGTCTCCTGGGAGGACGTCGCCCTGCTGACTCGCAGGGAAAGACGTACCG
  GCCAGGTGCTCGCCAGGACTACGCTGGCCGGGGGCTGCGACCTTAGAAGCTTCCTTCTGG
  ACGACCCTTCTCGAGCACCTGAGCCGGACAGAAACCGATGTTCCGCGNCCAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003247 unedited
  GGGGGCCTTGGAGATGGCACTTCCGGTCCAGTATGAGCCTGGGGNAGGGTCACAGGGTTG
  CCACCCGGGCTCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTT
  TTTTTTTTTTTTTTTTTTATAAAAAACCTTTTTTACAATTTATTTCCTGTTGTTAATCTT
  TAAAAATGAGGTTCTAGCTAAGTGCAGGGTTTCAGTGGTGAAATTTTGACCATGTGAACA
  CATAAATAAATATTTACAGTCTTTGGCAAAACACATGACGTTTCATCAACCTATACGATA
  AATTTGTTTAGAAAAACATAAATAATTTACAAAAAATATGGTACATTCTAAATACTCACA
  TCATCGTCACTCCCACACCATTGTACGGTTGACCCCACAACACAGAAACAGAAAACCTGC
  ACGCTGTTGACAGTCGCTACATTTAATGAAGTATCCCAACGCTTCGTTGGTCTCGGGAAT
  ACAGCTCCACACGCAAAAAAGTAAAAAGTGCAGCAAAACAACAACACAACGATCAACCTC
  AAAGGAAACAACAAATTTAATTTTATCAAAATGCAATGTGTACATTAAGACTAAAGTTAT
  GGATTGTTCCTGTTTGGCATAGAAATGTGATGACTATTAACAGAAAGGGGAAAAAGATTT
  GCCCCCTATCCATCATCAGACAGACAGACTTCTCTTACTAAACCCCTTATGTGGAGTGGG
  ATGAGTGACTATTTCCTGCAGAAAGTCATGCATCTTANAGCATAAAAACAAACCCNCCAA
  CAAAAAAAACAAAAACCAAAACCAACTTGTGCATATTACACATGACTGATTATTGGGTGT
  GCCCTGGCAAGACTAAATGCTGATTCTTTTCAGCGTTTGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003247
• ORF Size: 3519 bp
• Insert Size: 6000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.

Reference Data

• RefSeq: NM_003247.2, NP_003238.2
• RefSeq Size: 5826
• RefSeq ORF: 3519
• Locus ID: 7058
• Domains: tsp_1, VWC, EGF_CA, TSPN, tsp_3, EGF, EGF
• Protein Families: Druggable Genome
• Protein Pathways: ECM-receptor interaction, Focal adhesion, TGF-beta signaling pathway
• Gene Summary: The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration. [provided by RefSeq, Jul 2008]