Cadherin like 23 (CDH23) (NM_001171935) Human Tagged ORF Clone

CAT#: RC229771

CDH23 (Myc-DDK-tagged)-Human cadherin-related 23 (CDH23), transcript variant 8

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: Myc-DDK
• Symbol: CDH23
• Synonyms: CDHR23; PITA5; USH1D
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RC229771 representing NM_001171935
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGCGGTCCTGGTTCCAGCAGGATCCTATGGTGGGAGCATGCACCACAGGCACCAGGGCCTCACACCCCA
  AAGCCAACCCTGTGTGGCTGGATCCCTTCTGTCGGAACCTGGAGCTGGCCGCCCAGGCGGAGCATGAGGA
  TGACCTACCGGAGAACCTGAGTGAGATCGCCGACCTGTGGAACAGCCCCACGCGCACCCATGGAACTTTT
  GGGCGTGAGCCAGCAGCTGTCAAGCCTGATGATGACCGATACCTGCGGGCTGCCATCCAGGAGTATGACA
  ACATTGCCAAGCTGGGCCAGATCATTCGTGAGGGGCCAATCAAGGGCTCGCTGCTGAAGGTGGTCCTGGA
  GGATTACCTGCGGCTCAAAAAGCTCTTTGCACAGCGGATGGTGCAAAAAGCCTCCTCCTGCCACTCCTCC
  ATCTCTGAGCTGATACAGACTGAGCTGGACGAGGAGCCAGGAGACCACAGCCCAGGGCAGGGTAGCCTGC
  GCTTCCGCCACAAGCCACCAGTGGAGCTCAAGGGGCCCGATGGGATCCATGTGGTGCACGGCAGCACGGG
  CACGCTGCTGGCCACCGACCTCAACAGCCTGCCCGAGGAAGACCAGAAGGGCCTGGGCCGCTCGCTGGAG
  ACGCTGACCGCTGCCGAGGCCACTGCCTTCGAGCGCAACGCCCGCACAGAATCCGCCAAATCCACACCCC
  TGCACAAACTTCGCGACGTGATCATGGAGACCCCCCTGGAGATCACAGAGCTG
  
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
  ACAAGGATGACGACGATAAGGTTTAA
  Protein Sequence

  >RC229771 representing NM_001171935
  Red=Cloning site Green=Tags(s)
  
  MRSWFQQDPMVGACTTGTRASHPKANPVWLDPFCRNLELAAQAEHEDDLPENLSEIADLWNSPTRTHGTF
  GREPAAVKPDDDRYLRAAIQEYDNIAKLGQIIREGPIKGSLLKVVLEDYLRLKKLFAQRMVQKASSCHSS
  ISELIQTELDEEPGDHSPGQGSLRFRHKPPVELKGPDGIHVVHGSTGTLLATDLNSLPEEDQKGLGRSLE
  TLTAAEATAFERNARTESAKSTPLHKLRDVIMETPLEITEL
  
  TRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_001171935
• ORF Size: 753 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001171935.1, NP_001165406.1
• RefSeq ORF: 756
• Locus ID: 64072
• Protein Families: Transmembrane
• MW: 28.3 kDa
• Gene Summary: This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013]