LTK (NM_002344) Human Tagged ORF Clone

CAT#: RG214572

LTK (GFP-tagged) - Human leukocyte receptor tyrosine kinase (LTK), transcript variant 1

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: TurboGFP
• Symbol: LTK
• Synonyms: TYK1
• Vector: pCMV6-AC-GFP
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  ORF Nucleotide Sequence

  >RG214572 representing NM_002344
  Red=Cloning site Blue=ORF Green=Tags(s)
  
  TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
  GCCGCGATCGCC
  
  ATGGGCTGCTGGGGACAGCTGCTGGTGTGGTTCGGAGCCGCGGGCGCCATTCTCTGCTCTAGCCCGGGGT
  CCCAGGAGACTTTTCTGCGGTCCTCGCCCCTGCCGCTGGCAAGTCCCAGCCCCCGGGACCCGAAAGTCAG
  CGCCCCGCCTAGTATCTTGGAGCCAGCCTCCCCGCTGAATTCTCCGGGCACCGAGGGGTCTTGGCTGTTT
  TCTACCTGCGGGGCCAGCGGCCGGCATGGGCCCACACAGACACAATGTGACGGGGCGTACGCGGGGACCA
  GCGTGGTGGTGACCGTGGGGGCCGCCGGGCAGCTGAGAGGCGTGCAGCTGTGGCGCGTGCCGGGCCCTGG
  CCAGTATCTGATCTCAGCCTACGGAGCCGCGGGCGGCAAAGGCGCCAAGAACCACCTGTCGCGGGCGCAT
  GGCGTCTTCGTCTCAGCAATCTTCTCCCTCGGTCTCGGGGAGTCGCTGTACATCCTGGTGGGGCAGCAGG
  GAGAGGACGCCTGTCCCGGAGGTAGCCCGGAGAGCCAGCTCGTCTGCCTCGGGGAGTCTCGAGCCGTTGA
  AGAGCACGCGGCGATGGATGGGAGCGAAGGGGTCCCGGGGTCGCGGCGCTGGGCGGGAGGTGGCGGGGGT
  GGCGGGGGCGCCACCTACGTTTTCCGGGTGCGCGCTGGCGAGCTGGAACCGTTGCTGGTGGCGGCCGGAG
  GCGGCGGTCGGGCCTACCTGAGGCCGCGGGACCGAGGCCGGACTCAGGCCTCCCCCGAGAAACTGGAGAA
  CCGCTCGGAGGCGCCCGGGAGCGGCGGGAGAGGCGGGGCGGCAGGTGGTGGGGGCGGCTGGACGTCGCGG
  GCTCCCTCTCCGCAGGCCGGCCGCTCACTGCAGGAGGGGGCGGAGGGCGGCCAGGGCTGCTCCGAGGCTT
  GGGCGACCCTTGGCTGGGCCGCGGCCGGCGGCTTCGGGGGCGGCGGCGGGGCCTGCACTGCGGGCGGAGG
  CGGCGGCGGCTACAGGGGGGGCGACGCTTCAGAGACTGACAACCTCTGGGCTGATGGGGAAGATGGAGTA
  TCCTTCATACACCCCAGCAGCGAGCTCTTCCTGCAGCCTCTGGCAGTCACCGAGAACCACGGAGAGGTAG
  AGATCCGAAGGCACCTCAACTGCAGTCACTGCCCTTTGAGAGACTGCCAATGGCAGGCAGAGCTCCAGCT
  GGCTGAATGCCTGTGCCCAGAAGGCATGGAGCTAGCTGTGGATAACGTCACCTGCATGGACCTGCACAAG
  CCCCCAGGCCCTCTGGTTCTGATGGTGGCTGTGGTGGCAACCTCAACACTGAGCCTCCTTATGGTGTGTG
  GGGTCCTGATTCTGGTGAAGCAGAAGAAGTGGCAGGGCCTGCAGGAGATGAGGCTGCCGAGCCCTGAGCT
  TGAGCTGAGCAAGCTTCGAACCTCTGCCATCAGGACAGCCCCCAATCCCTATTATTGCCAGGTGGGGCTT
  GGCCCGGCCCAGTCCTGGCCTCTGCCACCAGGTGTCACCGAGGTTTCCCCAGCCAATGTTACTCTGCTCA
  GAGCCCTGGGCCATGGTGCCTTTGGGGAGGTGTATGAGGGACTGGTAATTGGCCTTCCTGGGGACTCCAG
  TCCCCTGCAGGTAGCTATCAAGACCCTGCCAGAACTCTGCTCGCCTCAGGATGAGCTGGATTTCCTCATG
  GAGGCCCTCATCATCAGCAAGTTTCGCCATCAGAACATTGTGCGGTGTGTGGGGCTCAGCCTCAGGGCCA
  CCCCTCGCCTCATTCTGCTGGAACTGATGTCTGGAGGGGACATGAAGAGTTTCCTGAGGCACAGTCGGCC
  ACACCTGGGCCAGCCATCACCTCTGGTCATGCGGGACCTGCTGCAACTGGCCCAGGACATAGCCCAGGGC
  TGCCACTACCTGGAGGAAAATCACTTCATCCACAGGGATATTGCCGCCCGGAACTGCCTGCTGAGCTGCG
  CTGGACCCAGCCGAGTGGCCAAGATTGGGGACTTTGGGATGGCACGAGATATCTACCGGGCCAGTTATTA
  CCGCAGGGGGGACCGGGCCTTGCTCCCAGTCAAGTGGATGCCCCCAGAGGCCTTCCTGGAGGGCATCTTC
  ACATCCAAGACAGATTCCTGGTCTTTTGGGGTGCTGCTCTGGGAGATCTTCTCACTGGGCTACATGCCCT
  ATCCTGGGCGCACCAACCAGGAGGTGCTGGACTTCGTCGTTGGAGGAGGCCGGATGGACCCTCCTAGGGG
  CTGCCCAGGGCCTGTGTACCGCATCATGACCCAGTGTTGGCAGCACGAGCCTGAGCTCCGCCCTAGCTTT
  GCCAGCATCTTGGAGCGTCTGCAGTACTGCACTCAGGACCCGGATGTGCTGAATTCACTCCTGCCAATGG
  AGCTGGGGCCCACCCCAGAGGAGGAAGGGACTTCTGGGCTGGGGAACAGATCTTTGGAGTGCCTAAGACC
  CCCACAGCCCCAGGAACTGAGTCCAGAGAAGTTGAAAAGCTGGGGAGGTAGCCCTCTTGGCCCCTGGCTG
  TCCTCTGGCCTCAAGCCCCTCAAATCCAGGGGCCTCCAACCTCAGAACCTTTGGAATCCCACTTATCGCT
  CC
  
  ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA
  Protein Sequence

  >RG214572 representing NM_002344
  Red=Cloning site Green=Tags(s)
  
  MGCWGQLLVWFGAAGAILCSSPGSQETFLRSSPLPLASPSPRDPKVSAPPSILEPASPLNSPGTEGSWLF
  STCGASGRHGPTQTQCDGAYAGTSVVVTVGAAGQLRGVQLWRVPGPGQYLISAYGAAGGKGAKNHLSRAH
  GVFVSAIFSLGLGESLYILVGQQGEDACPGGSPESQLVCLGESRAVEEHAAMDGSEGVPGSRRWAGGGGG
  GGGATYVFRVRAGELEPLLVAAGGGGRAYLRPRDRGRTQASPEKLENRSEAPGSGGRGGAAGGGGGWTSR
  APSPQAGRSLQEGAEGGQGCSEAWATLGWAAAGGFGGGGGACTAGGGGGGYRGGDASETDNLWADGEDGV
  SFIHPSSELFLQPLAVTENHGEVEIRRHLNCSHCPLRDCQWQAELQLAECLCPEGMELAVDNVTCMDLHK
  PPGPLVLMVAVVATSTLSLLMVCGVLILVKQKKWQGLQEMRLPSPELELSKLRTSAIRTAPNPYYCQVGL
  GPAQSWPLPPGVTEVSPANVTLLRALGHGAFGEVYEGLVIGLPGDSSPLQVAIKTLPELCSPQDELDFLM
  EALIISKFRHQNIVRCVGLSLRATPRLILLELMSGGDMKSFLRHSRPHLGQPSPLVMRDLLQLAQDIAQG
  CHYLEENHFIHRDIAARNCLLSCAGPSRVAKIGDFGMARDIYRASYYRRGDRALLPVKWMPPEAFLEGIF
  TSKTDSWSFGVLLWEIFSLGYMPYPGRTNQEVLDFVVGGGRMDPPRGCPGPVYRIMTQCWQHEPELRPSF
  ASILERLQYCTQDPDVLNSLLPMELGPTPEEEGTSGLGNRSLECLRPPQPQELSPEKLKSWGGSPLGPWL
  SSGLKPLKSRGLQPQNLWNPTYRS
  
  TRTRRLE - GFP Tag - V
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene Plasmid Map
• ACCN: NM_002344
• ORF Size: 2592 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002344.3, NP_002335.2
• RefSeq Size: 3135
• RefSeq ORF: 2595
• Locus ID: 4058
• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Gene Summary: The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]