IRF2BP1 (NM_015649) Human Untagged Clone

CAT#: SC100453

IRF2BP1 (untagged)-Human interferon regulatory factor 2 binding protein 1 (IRF2BP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IRF2BP1
• Synonyms: DKFZp434M154
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC100453 sequence for NM_015649 edited (data generated by NextGen Sequencing)
  ATGGCGTCTGTGCAGGCGTCCCGCCGCCAGTGGTGCTACCTGTGCGACCTGCCCAAGATG
  CCGTGGGCCATGGTGTGGGACTTCAGCGAGGCCGTGTGTCGCGGCTGCGTGAACTTCGAG
  GGCGCGGACCGCATCGAACTGCTCATCGATGCCGCCCGCCAGCTCAAGCGCAGCCACGTG
  CTCCCCGAGGGCCGCTCGCCCGGGCCCCCGGCCCTTAAGCACCCGGCCACCAAGGACCTG
  GCGGCGGCAGCCGCACAGGGGCCCCAGCTGCCGCCCCCGCAGGCCCAGCCCCAGCCGTCA
  GGGACCGGCGGCGGCGTGTCGGGCCAGGACCGCTATGACAGGGCCACATCATCAGGCCGC
  CTCCCCCTGCCCTCGCCCGCCCTGGAGTACACTCTGGGGTCCCGCCTGGCCAATGGGCTG
  GGCCGTGAGGAGGCCGTGGCTGAGGGGGCGCGAAGGGCCTTGCTTGGCTCCATGCCTGGC
  TTGATGCCCCCTGGGCTGCTGGCAGCTGCAGTGTCTGGCCTGGGAAGCCGAGGCCTGACG
  CTGGCACCCGGCTTGAGTCCTGCCCGTCCCCTCTTCGGCTCCGATTTCGAGAAAGAGAAG
  CAGCAGAGGAATGCGGACTGTCTGGCAGAACTGAACGAGGCCATGCGAGGCCGGGCAGAG
  GAATGGCACGGGCGCCCCAAAGCAGTGCGGGAACAGCTACTGGCGCTGTCCGCCTGCGCC
  CCGTTCAATGTGCGCTTCAAGAAGGATCACGGGCTGGTGGGGCGAGTGTTCGCCTTCGAT
  GCTACTGCCCGTCCTCCAGGATACGAGTTCGAGCTGAAGCTCTTCACCGAATACCCCTGT
  GGTTCCGGCAATGTGTACGCCGGCGTCCTGGCAGTGGCTCGCCAGATGTTCCACGATGCT
  CTGCGGGAGCCGGGCAAGGCACTGGCTTCTTCGGGCTTCAAGTACCTCGAATATGAACGC
  CGGCATGGATCAGGAGAATGGCGGCAGCTGGGCGAGCTGCTTACCGACGGCGTCCGCAGC
  TTCCGCGAGCCAGCTCCCGCGGAGGCCCTGCCCCAGCAGTACCCAGAGCCGGCCCCTGCG
  GCTCTCTGTGGCCCACCCCCGCGAGCCCCATCCCGGAACCTGGCGCCCACGCCGCGCCGT
  CGCAAGGCATCCCCCGAGCCGGAGGGCGAGGCGGCTGGGAAGATGACCACCGAGGAGCAG
  CAGCAACGGCACTGGGTGGCACCCGGCGGCCCGTACTCCGCTGAGACCCCTGGTGTGCCC
  TCGCCCATTGCCGCCCTGAAGAATGTGGCCGAAGCCCTGGGCCACTCACCCAAGGACCCT
  GGCGGAGGCGGGGGGCCTGTGCGTGCAGGGGGCGCCAGCCCTGCAGCCTCCTCCACGGCC
  CAGCCGCCAACCCAGCATCGCCTTGTGGCCCGCAACGGCGAAGCAGAAGTCAGTCCCACA
  GCGGGGGCCGAAGCTGTCAGCGGGGGTGGCAGCGGCACTGGGGCGACCCCTGGGGCCCCC
  CTGTGCTGTACCCTGTGCAGGGAGCGGCTAGAAGACACCCACTTCGTCCAGTGCCCCTCG
  GTGCCCGGACACAAGTTCTGCTTTCCCTGCTCCCGGGAGTTCATCAAGGCGCAGGGCCCG
  GCCGGGGAGGTGTACTGCCCGAGCGGAGACAAGTGCCCGCTGGTCGGCTCCTCCGTGCCC
  TGGGCCTTCATGCAGGGCGAGATCGCCACCATCCTTGCTGGAGACATCAAAGTTAAGAAA
  GAACGGGACCCCTAG
  
  Clone variation with respect to NM_015649.1
  654 c=>g;1530 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015649 unedited
  GTTGTAACGCCCGCCAGTCGNCGTTATGGGCGGTAGGCGTGCACGGTGGGAGGTCTATAT
  AAGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGC
  CGCGAATTCGGCACGAGGGGGAGCCCGAGGCGGCGGCGCTCGCGGCCCATCGTGGGGCCC
  GAGCTGTGCGCCTCGGCTCGGAGCCCGGACCGGGCGGGGGCGCCGACGTGCCTCAGCCTG
  CCTTCGCGAGGGAGGCGGGAGTGAGCAGAAAGGCTTAGGGCCCAGGGGGCGGGGAAGGGG
  GGCCGGGCCTGGATCCGGCGGGGAGGCCGAGCCGGAGGCCGGACCGTGGCTCGCGCTGTC
  CCCGGGACGCGGATCGAACGTTGGCGGCGCGGATCGCACGTCGGCGGCCGGTGGAACGCG
  GGAGCTGGGCGGCGCGCGGACTGGGGCCATGGCGTCTGTGCAGGCGTCCCGCCGCCAGTG
  GTGCTACCTGTGCGACCTGCCCAAGATGCCGTGGGCCATGGTGTGGGACTTCAGCGAGGC
  CGTGTGTCGCGGCTGCGTGAACTTCGAGGGCGCGGACCGCATCGAACTGCTCATCGATGC
  CGCCCGCCAGCTCAAGCGCAGCCACGTGCTCCCCGAGGGCCGCTCGCCCGGGCCCCCGGC
  CCTTAAGCACCCGGTCACCAAGGACCTGGCGGCGGCAGCCGCACAGGGGCCCCCAGCTGC
  CGCCCCCGCAAGCCCAGTCCCAGCCGTTAGGGACCGGGCGGCGGTTGTGTCCGGCCCACC
  ACCGCTTTTAACCAGGCCCCCATTTTTAAGGCCGGCTACCCCTGCCCTCTGCCCGCCTTG
  AAGAACACTCTTGTGAGTCCGCCCTGGCCAATGGCCTGGTCCTTGATGTGCCCTGGCCTC
  AGCGGCCCCCACAGTCCTTTTTTGCCTTAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015649 unedited
  NNNCGGTATAGCTATGNNACCGCGGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTT
  TTTTTTTTTTGAAAAAAAAAACCCATCTTTCGGTTTATTGAAGGAGCAAAAGGGAGCGGG
  GGGTGGGGGGGTGGGAATTAAATGCTTTTGCCTCGTTTATAAAGAGCGAGTTTTCAGGAG
  GTCCCTTCTCAAGGAGGAGGGGGGCACCTCTCCCCCAACTACAAGCAGCAGCAAAGCCAA
  GCCCAGGAGGACAGAGGGAAACTGGAGGGGCCAAGGGACCCCAAACACCCCCTCGGACAG
  GAGCCACAAGCTTTCTCCCCCCACCCACCATGCATCTACCCCAGGGGACCCCTCTGGGTG
  GAAGAAGGGAGTCTGTTCCCACATAGAGGTGGCCCTGGGCTTGGTCCGGGAGGGAATAAT
  TTATCCGCGGCCCCCGTGGGTGGCAAAGGGGCCCAGGGCAATATCCTGGAGGCCGTGGTT
  GCCCAAGGGTCCCCTTCTTTCTTAACTTTGATGTCTCCCCCAAAGATGGGGGCGATCTCT
  CCCTGACTGAAAGCCCCTTGCCCCGGTTGAACCCACCAACGGGCATTTGTCTTCCGCTGT
  GACAAGACACCTCCCCCGCCCGGCCCTCGCGCCTTTTGAAATCCCCCCGCGGCCAGGAAA
  GCCACACTCTTTGCCCCCGCCCCCATGGGGGGCCCGTGACACAAAAAGGGCGTCTTTATC
  TCCGCTCCCTTTTCCCAGGGACACCCACACGGGGGGCCCCCCAGGGGATTTCCCAGCGCC
  CCTCTGTTACCCCTATAGGAACGTTTTATACCCCGCGCGTGTGGTCTACCCTCTTCTTTC
  ACCGTTTCGTGCCCACCATTAGAAACCAGCTTGGGTGACCTCGCCCCCCGCGCCAGCTCG
  CGCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015649
• ORF Size: 1755 bp
• Insert Size: 800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_015649.1, NP_056464.1
• RefSeq Size: 2630
• RefSeq ORF: 1755
• Locus ID: 26145
• Protein Families: Druggable Genome
• Gene Summary: Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation. [UniProtKB/Swiss-Prot Function]