IRF2BP1 (NM_015649) Human Untagged Clone

CAT#: SC324300

IRF2BP1 (untagged)-Human interferon regulatory factor 2 binding protein 1 (IRF2BP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IRF2BP1
• Synonyms: DKFZp434M154
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_015649.1 CGGCGGCCGTTGCAGCGGCGGCGGCGAGAGCGGCGGGAGCCCGAGGCGGCGGCGCTCGCG
  GCCCATCGTGGGGCCCGAGCTGTGCGCCTCGGCTCGGAGCCCGGACCGGGCGGGGGCGCC
  GACGTGCCTCAGCCTGCCTTCGCGAGGGAGGCGGGAGTGAGCAGAAAGGCTTAGGGCCCA
  GGGGGCGGGGAAGGGGGGCCGGGCCTGGATCCGGCGGGGAGGCCGAGCCGGAGGCCGGAC
  CGTGGCTCGCGCTGTCCCCGGGACGCGGATCGAACGTTGGCGGCGCGGATCGCACGTCGG
  CGGCCGGTGGAACGCGGGAGCTGGGCGGCGCGCGGACTGGGGCCATGGCGTCTGTGCAGG
  CGTCCCGCCGCCAGTGGTGCTACCTGTGCGACCTGCCCAAGATGCCGTGGGCCATGGTGT
  GGGACTTCAGCGAGGCCGTGTGTCGCGGCTGCGTGAACTTCGAGGGCGCGGACCGCATCG
  AACTGCTCATCGATGCCGCCCGCCAGCTCAAGCGCAGCCACGTGCTCCCCGAGGGCCGCT
  CGCCCGGGCCCCCGGCCCTTAAGCACCCGGCCACCAAGGACCTGGCGGCGGCAGCCGCAC
  AGGGGCCCCAGCTGCCGCCCCCGCAGGCCCAGCCCCAGCCGTCAGGGACCGGCGGCGGCG
  TGTCGGGCCAGGACCGCTATGACAGGGCCACATCATCAGGCCGCCTCCCCCTGCCCTCGC
  CCGCCCTGGAGTACACTCTGGGGTCCCGCCTGGCCAATGGGCTGGGCCGTGAGGAGGCCG
  TGGCTGAGGGGGCGCGAAGGGCCTTGCTTGGCTCCATGCCTGGCTTGATGCCCCCTGGGC
  TGCTGGCAGCTGCAGTGTCTGGCCTGGGAAGCCGAGGCCTGACGCTGGCACCCGGCTTGA
  GTCCTGCCCGTCCCCTCTTCGGCTCCGATTTCGAGAAAGAGAAGCAGCAGAGGAATGCGG
  ACTGTCTGGCAGAACTGAACGAGGCCATGCGAGGCCGCGCAGAGGAATGGCACGGGCGCC
  CCAAAGCAGTGCGGGAACAGCTACTGGCGCTGTCCGCCTGCGCCCCGTTCAATGTGCGCT
  TCAAGAAGGATCACGGGCTGGTGGGGCGAGTGTTCGCCTTCGATGCTACTGCCCGTCCTC
  CAGGATACGAGTTCGAGCTGAAGCTCTTCACCGAATACCCCTGTGGTTCCGGCAATGTGT
  ACGCCGGCGTCCTGGCAGTGGCTCGCCAGATGTTCCACGATGCTCTGCGGGAGCCGGGCA
  AGGCACTGGCTTCTTCGGGCTTCAAGTACCTCGAATATGAACGCCGGCATGGATCAGGAG
  AATGGCGGCAGCTGGGCGAGCTGCTTACCGACGGCGTCCGCAGCTTCCGCGAGCCAGCTC
  CCGCGGAGGCCCTGCCCCAGCAGTACCCAGAGCCGGCCCCTGCGGCTCTCTGTGGCCCAC
  CCCCGCGAGCCCCATCCCGGAACCTGGCGCCCACGCCGCGCCGTCGCAAGGCATCCCCCG
  AGCCGGAGGGCGAGGCGGCTGGGAAGATGACCACCGAGGAGCAGCAGCAACGGCACTGGG
  TGGCACCCGGCGGCCCGTACTCCGCTGAGACCCCTGGTGTGCCCTCGCCCATTGCCGCCC
  TGAAGAATGTGGCCGAAGCCCTGGGCCACTCACCCAAGGACCCTGGCGGAGGCGGGGGGC
  CTGTGCGTGCAGGGGGCGCCAGCCCTGCAGCCTCCTCCACGGCCCAGCCGCCAACCCAGC
  ATCGCCTTGTGGCCCGCAACGGCGAAGCAGAAGTCAGTCCCACAGCGGGGGCCGAAGCTG
  TCAGCGGGGGTGGCAGCGGCACTGGGGCGACCCCTGGGGCCCCCCTGTGCTGTACCCTGT
  GCAGGGAGCGGCTGGAAGACACCCACTTCGTCCAGTGCCCCTCGGTGCCCGGACACAAGT
  TCTGCTTTCCCTGCTCCCGGGAGTTCATCAAGGCGCAGGGCCCGGCCGGGGAGGTGTACT
  GCCCGAGCGGAGACAAGTGCCCGCTGGTCGGCTCCTCCGTGCCCTGGGCCTTCATGCAGG
  GCGAGATCGCCACCATCCTTGCTGGAGACATCAAAGTTAAGAAAGAACGGGACCCCTAGG
  CTACCACTGCCTCCAGGCTACTGCCCTCTGCCCCTTTGCCACCCACCGCTGCCGCGGATA
  AATTATTCCCTCCCCGACCCAGCCCAGTGCCACCTCTATCTGTGTACATACTCCCTTCTT
  CCACCCAGATGGGTCCCCTGGGGTAGATGCATTGTGGGTGGGGGGAGAAAGCTTGTGGCT
  CCTGTCCGAGGGGGTGTTTGGGGTCCCTTGGCCCCTCCAGTTTCCCTCTGTCCTCCTTGG
  CTTGGCTTTGCTGCTGCTTGTAGTTGGGGGAGAGGTGCCCCCCTCCTCCTTGAGAAGGGA
  CCTCCTGAAAACTCGCTCTTTATAAACGAGGCAAAAGCATTTAATTCCCACCCCCCCACC
  CCCCGCTCCCTTCTGCTCCTTCAATAAACCGAAAGATGGGTTTTTTTTTTCAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015649.1 unedited
  GGCTACCCCTGCAGCCTCCCGCTGTTTTGACCTCCAAGAAGACACCGGGACCGATCCAGC
  CTCCGGACTCTAGCCTAGGCCGCGGGACGGATAACAATTTCACACAGGAAACAGCTATGA
  CCATTAGGCCTATTTAGGTGACACTATAGAACAAGTTTGTACAAAAAAGCAGGCTGGTAC
  CGGTCCGGAATTCCCGGGATCGGCGGCCGTTGCAGCGGCGGCGGCGAGAGCGGCGGGAGC
  CCGAGGCGGCGGCGCTCGCGGCCCATCGTGGGGCCCGAGCTGTGCGCCTCGGCTCGGAGC
  CCGGACCGGGCGGGGGCGCCGACGTGCCTCAGCCTGCCTTCGCGAGGGAGGCGGGAGTGA
  GCAGAAAGGCTTAGGGCCCAGGGGGCGGTGAAGGGGCGTCCCCTCCGGATCTTGTGTCTC
  ACAAATCCAGTTGAAAAACTGGTGCACGTGATCTCGCCAAATTACAAAAGA
• Restriction Sites: Please inquire
• ACCN: NM_015649
• ORF Size: 1755 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_015649.1, NP_056464.1
• RefSeq Size: 2630
• RefSeq ORF: 1755
• Locus ID: 26145
• Protein Families: Druggable Genome
• Gene Summary: Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation. [UniProtKB/Swiss-Prot Function]