PIK3AP1 (NM_152309) Human Untagged Clone

CAT#: SC100911

PIK3AP1 (untagged)-Human phosphoinositide-3-kinase adaptor protein 1 (PIK3AP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PIK3AP1
• Synonyms: BCAP
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_152309, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCAGCCTCAGGGGTGCCCAGAGGATGCGACATCCTCATCGTCTACAGCCCGGATGCCGAGGAATGGT
  GCCAGTACCTGCAGACCCTGTTCCTGTCCAGTCGGCAGGTCCGCAGCCAGAAGATACTGACTCACAGGCT
  GGGCCCCGAGGCCTCCTTCTCGGCAGAGGACCTAAGCCTTTTCCTCAGCACCCGCTGTGTCGTGGTGCTG
  CTGTCCGCGGAGCTGGTGCAGCACTTCCACAAGCCCGCCTTGCTGCCCCTGCTGCAGAGAGCTTTCCATC
  CTCCGCACCGCGTGGTCAGGCTGCTCTGCGGCGTGCGGGACAGCGAGGAGTTCCTAGACTTCTTTCCAGA
  TTGGGCCCATTGGCAGGAGCTCACCTGTGACGATGAGCCAGAGACCTACGTGGCAGCTGTGAAAAAAGCC
  ATTTCCGAAGATTCTGGCTGTGACTCAGTCACTGACACTGAGCCTGAGGACGAGAAGGTTGTTTCCTACT
  CGAAGCAGCAGAACCTGCCGACGGTGACTTCACCTGGGAACCTGATGGTGGTGCAGCCGGACCGCATTCG
  CTGTGGGGCAGAAACCACTGTCTATGTTATTGTGAGATGTAAGCTGGATGACAGGGTGGCGACAGAAGCA
  GAGTTTTCTCCTGAGGATTCTCCCTCTGTAAGGATGGAAGCCAAGGTGGAGAATGAGTACACCATTTCAG
  TGAAGGCTCCCAACCTTTCATCTGGGAACGTTTCTCTGAAGATATATTCTGGAGACTTAGTGGTGTGTGA
  AACCGTTATCAGCTATTATACTGACATGGAAGAAATTGGGAATTTATTGTCCAATGCCGCGAATCCTGTG
  GAATTCATGTGTCAGGCCTTTAAAATTGTGCCCTACAACACAGAGACCCTTGATAAACTGCTAACCGAAT
  CCCTGAAGAACAATATCCCTGCAAGCGGACTGCACCTCTTTGGAATCAACCAGCTGGAAGAAGAAGATAT
  GATGACAAATCAGAGGGATGAAGAGCTGCCCACCCTGTTGCATTTTGCTGCGAAGTATGGACTGAAGAAC
  CTCACTGCCTTGTTGCTCACCTGCCCAGGAGCCCTGCAGGCGTACAGCGTGGCCAACAAGCATGGCCACT
  ACCCCAACACCATCGCTGAGAAACACGGCTTCAGGGACCTGCGGCAGTTCATCGACGAGTATGTGGAAAC
  GGTGGACATGCTCAAGAGTCACATTAAAGAGGAACTGATGCACGGGGAGGAGGCTGATGCTGTGTACGAG
  TCCATGGCCCACCTTTCCACAGACCTGCTTATGAAATGCTCGCTCAACCCCGGCTGTGACGAGGATCTCT
  ATGAGTCCATGGCTGCCTTTGTCCCAGCTGCCACTGAAGACCTCTATGTTGAAATGCTTCAGGCCAGTAC
  ATCTAACCCAATCCCTGGAGATGGTTTCTCTCGGGCCACTAAGGACTCTATGATCCGCAAGTTTTTAGAA
  GGCAACAGCATGGGAATGACCAATCTGGAGAGAGATCAGTGCCATCTTGGTCAGGAAGAAGATGTTTATC
  ACACGGTGGATGACGATGAGGCCTTTTCTGTGGACCTGGCCAGCAGGCCCCCTGTCCCAGTGCCCAGACC
  AGAGACCACTGCTCCTGGTGCTCACCAGCTGCCTGACAACGAACCATACATTTTTAAAGTTTTTGCAGAA
  AAAAGTCAAGAGCGGCCTGGGAATTTCTACGTTTCCTCAGAGAGCATCAGGAAAGGGCCGCCCGTCAGAC
  CATGGAGGGACAGGCCCCAGTCGAGTATATATGACCCTTTTGCGGGAATGAAAACGCCAGGCCAGCGGCA
  GCTTATCACCCTCCAGGAGCAGGTGAAGCTGGGCATTGTCAACGTGGATGAGGCTGTGCTCCACTTCAAA
  GAGTGGCAGCTCAACCAGAAGAAACGATCGGAGTCCTTTCGTTTCCAGCAGGAAAATCTTAAACGGCTAA
  GAGACAGCATCACCCGAAGACAGAGAGAGAAGCAAAAATCAGGAAAGCAGACAGACTTGGAGATCACGGT
  CCCAATTCGGCACTCACAGCACCTGCCTGCAAAAGTGGAGTTTGGAGTCTATGAGAGTGGCCCCAGGAAA
  AGTGTCATTCCCCCTAGGACGGAGCTGAGACGAGGAGACTGGAAAACAGACAGCACCTCCAGCACAGCAA
  GTAGCACAAGTAACCGCTCCAGCACCCGGAGCCTCCTCAGTGTGAGCAGCGGGATGGAAGGGGACAACGA
  GGATAATGAAGTCCCTGAGGTTACCAGAAGTCGCAGTCCAGGCCCCCCACAAGTGGATGGGACACCCACC
  ATGTCCCTCGAGAGACCCCCCAGGGTGCCTCCGAGAGCTGCCTCACAGAGGCCTCCGACCAGGGAGACCT
  TCCATCCTCCTCCACCTGTTCCACCCAGAGGACGCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_152309 unedited
  GCGGCCCGCGAATTCGCACGAGGGTACTGAACCTCCGGGAGCTTTTGTTCTCTGTGGAAG
  CCTGAGCAAGGGGTGCCCAGAGGATGCGACATCCTCATCGTCTACAGCCCGGATGCCGAG
  GAATGGTGCCAGTACCTGCAGACCCTGTTCCTGTCCAGTCGGCAGGTCCGCAGCCAGAAG
  ATACTGACTCACAGGCTGGGCCCCGAGGCCTCCTTCTCGGCAGAGGACCTAAGCCTTTTC
  CTCAGCACCCGCTGTGTCGTGGTGCTGCTGTCCGCGGAGCTGGTGCAGCACTTCCACAAG
  CCCTCCTTGCTGCCCCTGCTGCAGAGAGCTTTCCATCCTCCGCACCGCGTGGTCAGGCTG
  CTCTGCGGCGTGCGGGACAGCGAGGAGTTCCTAGACTTCTTTCCAGATTGGGCCCATTGG
  CAGGAGCTCACCTGTGACGATGAGCCAGAGACCTACGTGGCAGCTGTGAAAAAAGCCATT
  TCCGAAGATTCTGGCTGTGACTCAGTCACTGACACTGAGCCTGAGGACGAGAAGGTTGTT
  TCCTACTCGAAGCAGCAGAACCTGCCGACGGTGACTTCACCTGNGAACCTGATGGGTGGT
  GCAGCCGGACCGCATTCGCTGTGGGGCAGAAACCACTGTCTATGTTATTGTGAGATGTAA
  GCTGGATGACAGGGTGGCGACAGAAGCAGAGTTTTCTCCTGGAGATTCTCCCTCTGTAAG
  GATGGGAGCCAAGGTGGGANAATGAGTACACCATTTCAAGTGAAGGCTCCCAACCTTTCA
  TTGNGGNAACGTTTCTCTGAAGAATATTCTGGAGACTTAAGGGGGGGTGAAACCGTATCA
  GCTTTATACTGACATGGAAGAATTGGGNAATTTATT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_152309 unedited
  GGTACACTATGNACCGCGCCGCATTCTAGNGATCGGTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTCATCCAGATTATTTCATTTTCTTCTTTTACATATAACCAACCATTTTGGATG
  TTAAAGGAACAACCAGTGAGGGCTTAAAATCTGCTGCTTTTGACTTGGCACTCCTGATCA
  GTTCCATCCGTGTCTCAAGTGTATCACATTCACGAGACAAGGCTTCTCATCAGCAATTTC
  AATTTTATGTTTTCTACTTATTTTTATATAAGAATACAATGCACCAAAATATTCATATAT
  TGCACAAACAGTGATGTGCATACAAAGATGCTAACAACATTGGCTGGTAATAGGCTTTAC
  CATGTTATGATCTAAATGCTTGTTCATCAAAAAATGTACAAAATTCTAAGTTTGGCATCC
  AAAAGGGGGCTTACAGTTATTGAATATTTTTCCCAGCCCTATTTTAAATCAAATTCAAGT
  TTGCCTATGACAAAGACTGTCTATAAGTAACAGGGCAAGCATACCAACATCAAAATTATT
  CTTCTTCTTATCTCACGTGCCCCTATTTCTCCCAAATAAGTGACAAGGAGAGTAAAAGGA
  TCACTGAGGGAACATTTGAAGAATGCTACTAAGTGCCAGGTCCTGTACAAGGTAATTAAT
  TACTACAAACACTCTCGTGATGGACATGGCCAATAGTGTATTTTGTCAAAAACAAAAACA
  AACCCNAGATTCCAGAGCTGTTTCTGACAAGAAGTCCTGTTTCAGTACTCTTCAGTATGA
  GTCCCTACTTGCGGGACTGAAGAATGAAATTGAGAAAGAACCTTTATCTTTAGAAAAGAC
  CCAATAAAACTTACTTAATGGGTCATTAATGTGGATTTTTTACTTCGGGGGGATAGAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_152309
• ORF Size: 2418 bp
• Insert Size: 4700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_152309.2, NP_689522.2
• RefSeq Size: 4817
• RefSeq ORF: 2418
• Locus ID: 118788
• Protein Families: Druggable Genome
• Protein Pathways: B cell receptor signaling pathway
• Gene Summary: Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL. [UniProtKB/Swiss-Prot Function]