PEA15 (NM_003768) Human Untagged Clone

CAT#: SC108132

PEA15 (untagged)-Human phosphoprotein enriched in astrocytes 15 (PEA15)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PEA15
• Synonyms: HMAT1; HUMMAT1H; MAT1; MAT1H; PEA-15; PED; PED-PEA15; PED/PEA15
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_003768 edited
  ATGGCTGAGTACGGGACCCTCCTGCAAGACCTGACCAACAACATCACCCTTGAAGATCTA
  GAACAGCTCAAGTCGGCCTGCAAGGAAGACATCCCCAGCGAAAAGAGTGAGGAGATCACT
  ACTGGCAGTGCCTGGTTTAGCTTCCTGGAGAGCCACAACAAGCTGGACAAAGACAACCTC
  TCCTACATTGAGCACATCTTTGAGATCTCCCGCCGTCCTGACCTACTCACTATGGTGGTT
  GACTACAGAACCCGTGTGCTGAAGATCTCTGAGGAGGATGAGCTGGACACCAAGCTAACC
  CGTATCCCCAGTGCCAAGAAGTACAAAGACATTATCCGGCAGCCCTCTGAGGAAGAGATC
  ATCAAATTGGCTCCCCCACCGAAGAAGGCCTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003768 unedited
  GTTTCAGAATTTGTAATACGACTTCACTATANNGGCGGCCGCGCAATTCGGCACGAGGGG
  ACGCTGCTTAGGAACCGGGGACTCAGGAGTGCCCGCGCCCTGAGCGCTCAGCTCCAGAGG
  CGTCATGGCTGAGTACGGGACCCTCCTGCAAGACCTGACCAACAACATCACCCTTGAAGA
  TCTAGAACAGCTCAAGTCGGCCTGCAAGGAAGACATCCCCAGCGAAAAGAGTGAGGAGAT
  CACTACTGGCAGTGCCTGGTTTAGCTTCCTGGAGAGCCACAACAAGCTGGACAAAAGACA
  ACCTCTCCTACATTGAGCACATCTTTGAGATCTCCCGCCGTCCTGACCTACTCACTATGG
  TGGTTGACTACAGAACCCGTGTGCTGAAGATCTCTGAGGAGGATGAGCTGGACACCAAGC
  TAACCCGTATCCCCAGTGCCAAGAAGTACAAAGACATTATCCGGCAGCCCTCTGAGGAAG
  AGATCATCAAATTGGCTCCCCCACCGAAGAAGGCCTGAGCAAGGGGGAGGAAGAGGAGGA
  AGGTTGGACCTTCATCAGACCACTCCCTTCCCCCATCCTCCAGGAGAGGGGGCAAGGGCA
  ACCCACCATCTACCCACTTACTAACCTGGTCCTAACCCCCTTACTGTGCGCGTGTGTGTG
  CGTGTGCGCACGCTCTGGCTGTTTGTCTATATGTCTAGCTCATCTAGTTCCTCTTCTTAA
  GGGATGGGGGTCACGCGCTAGGGGGAGGGGCCTGAGTTTCCCCACTTTAAGAGGAAGTGG
  GGGCTATTCTATGCAAATAGAAATCAGCACATTCCTTCTACTTTCCTTTTCTCAACTCCC
  CCATATCTTTAAAGTGTGGAAGCCAGAAGGACCTGCATTTTCCTACATTTGAGAGCTGAC
  ATANGGGTTACGTATGGAGAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003768 unedited
  GAACGCCGCCGCTTACTANATCGAGTTTTTTTTTTTTTTTTTTGGCAGTGCAGTTTTAAT
  ATACATATATGTAGAATATATATGTACACACAGTTAGCACGGTCAGGGTGGGGAGGGGCA
  TCTTGGGGTAGGCAGGAGGCTGGGGTCACTCACTGTACTGTAGTGATGTGGCTAGGAGGT
  GTTCACAAGCCCAGGGGGCCAGGATATCTAGTAAAGAAGGGTTTCCTAAGTAAGTCCCTT
  CCGGGATTGAATTGGGGTGGGGATCGGTGCAAAGGAAAACACTGTAGTTAACTTCTTTCT
  GGCTTGGGATGTTCTTCACCAAGGAGAGAGGGAAGGTTGCCTACAATAACCAAGTTGGGA
  CCCTATAGATGGTGGTGTCAGGATTCGTGTTAAAACCTAAGGGTCTCATTCTTCAACCTC
  CCTAGGTTTAGAGTGCAACAGTCTGAGTAGGAACAACTGAGTGGAAGAGGGGGCTCCCCT
  CTCTCTGCCCTCATCCCCATCTCAGGCTCAGTGGTACATGTTCCCAGCACAGTCTCTCCA
  GAGTACAGGTGGGTGGGGGCATCTAACGCTGGCTGCTCCATGGGGTTTGATCTTAGGGAC
  CAGGAAAGGATCCCTGGCTCATACCTATGCTAGGCCCATGAGAGACAAAAAGGGACCTGC
  TGGTACTCANGAAACAGTCCAGCACAGGAGTACAAACATGGAACTCTGGCTTTTCTTTGC
  CCCTTCCAGGTGGGGGTTGAAGTGGTCTCTTTGCCTTTCGTCCCCACTGCTTTTTCCTGG
  ATCCACCCTACTCTNCCATACCTTACCCCTATGTCAGCTCCTCAATGTAGGAAAATGCAN
  GTTCTTTCTGCTTCCACACTTAAAGAATGGGGGGAGTGGAGGAAAGGAANTAGAAGNATG
  TGCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003768
• ORF Size: 393 bp
• Insert Size: 1700
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_003768.

Reference Data

• RefSeq: NM_003768.2, NP_003759.1
• RefSeq Size: 2486
• RefSeq ORF: 393
• Locus ID: 8682
• Domains: DED
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
  Transcript Variant: This variant (2) lacks two alternate exons in the 5' region and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (b) has a shorter N-terminus than isoform a. Variants 2 and 3 encode the same isoform (b).