TXNL2 (GLRX3) (NM_006541) Human Untagged Clone

CAT#: SC108544

GLRX3 (untagged)-Human glutaredoxin 3 (GLRX3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GLRX3
• Synonyms: GLRX4; GRX3; GRX4; PICOT; TXNL2; TXNL3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC108544 sequence for NM_006541 edited (data generated by NextGen Sequencing)
  ATGGCGGCGGGGGCGGCTGAGGCAGCTGTAGCGGCCGTGGAGGAGGTCGGCTCAGCCGGG
  CAGTTTGAGGAGCTGCTGCGCCTCAAAGCCAAGTCCCTCCTTGTGGTCCATTTCTGGGCA
  CCATGGGCTCCACAGTGTGCACAGATGAACGAAGTTATGGCAGAGTTAGCTAAAGAACTC
  CCTCAAGTTTCATTTGTGAAGTTGGAAGCTGAAGGTGTTCCTGAAGTATCTGAAAAATAT
  GAAATTAGCTCTGTTCCCACTTTTCTGTTTTTCAAGAATTCTCAGAAAATCGACCGATTA
  GATGGTGCACATGCCCCAGAGTTGACCAAAAAAGTTCAGCGACATGCATCTAGTGGCTCC
  TTCCTACCCAGCGCTAATGAACATCTTAAAGAAGATCTCAACCTTCGCTTGAAGAAATTG
  ACTCATGCTGCCCCCTGCATGCTGTTTATGAAAGGAACTCCTCAAGAACCACGCTGTGGT
  TTCAGCAAGCAGATGGTGGAAATTCTTCACAAACATAATATTCAGTTTAGCAGTTTTGAT
  ATCTTCTCAGATGAAGAGGTTCGACAGGGACTCAAAGCCTATTCCAGTTGGCCTACCTAT
  CCTCAGCTCTATGTTTCTGGAGAGCTCATAGGAGGACTTGATATAATTAAGGAGCTAGAA
  GCATCTGAAGAACTAGATACAATTTGTCCCAAAGCTCCCAAATTAGAGGAAAGGCTCAAA
  GTGCTGACAAATAAAGCTTCTGTGATGCTCTTTATGAAAGGAAACAAACAGGAAGCAAAA
  TGTGGATTCAGCAAACAAATTCTGGAAATACTAAATAGTACTGGTGTTGAATATGAAACA
  TTCGATATATTGGAGGATGAAGAAGTTCGGCAAGGATTAAAAGCTTACTCAAATTGGCCA
  ACATACCCTCAGCTGTATGTGAAAGGGGAGCTGGTGGGAGGATTGGATATTGTGAAGGAA
  CTGAAAGAAAATGGTGAATTGCTGCCTATACTGAGAGGAGAAAATTAA
  
  Clone variation with respect to NM_006541.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006541 unedited
  NGGGGCANCACANTTTTCCCNCCCCCCGGTTTAAATTTGTATACAATCATATAGGCGGCC
  GCGNAATTCGCACCAGGCATGGCGGCGGGGGCGGCTGAGGCAGCTGTAGCGGCCGTGGAG
  GAGGTCGGCTCAGCCGGGCAGTTTGAGGAGCTGCTGCGCCTCAAAGCCAAGTCCCTCCTT
  GTGGTCCATTTCTGGGCACCATGGGCTCCACAGTGTGCACAGATGAACGAAGTTATGGCA
  GAGTTAGCTAAAGAACTCCCTCAAGTTTCATTTGTGAAGTTGGAAGCTGAAGGTGTTCCT
  GAAGTATCTGAAAAATATGAAATTAGCTCTGTTCCCACTTTTCTGTTTTTCAAGAATTCT
  CAGAAAATCGACCGATTAGATGGTGCACATGCCCCAGAGTTGACCAAAAAAGTTCAGCGA
  CATGCATCTAGTGGCTCCTTCCTACCCAGCGCTAATGAACATCTTAAAGAAGATCTCAAC
  CTTCGCTTGAAGAAATTGACTCATGCTGCCCCCTGCATGCTGTTTATGAAAGGAACTCCT
  CAAGAACCACGCTGTGGTTTCAGCAAGCAGATGGTGGAAATTCTTCACANACATAATATT
  CAGTTTAGCAGTTNTGATATCTTCTCAGATGAAGAGGGTCGACAGGGACTCANAGCCTAT
  TCCAGTTGGCCTACCTATCCTCAGCTCTATGTTTCTGGAGAGCTNCATAGAGGACTTGAT
  ATAATAAGGAGCTAGAAGCATCTGAAGAACTAGATACCATNTGTCCCANAGCTCCCAAAN
  TAGAGGAAAAGCTCAAAGTGCTGACAAATAAAGCTTCTGTGATGCTCTTTTATGAAGGGA
  ACCAACNGAAGCAAAATTTGGATTCAGCAAACCAATTCTGGAAANTACTAATAGTACTGG
  NNNGTGATATGAAACATTCGATTATTGGAGATGAANAAAGTCGCCAGGGATTNAAAGCTA
  CTCAAATGGCCCACATACCCTCCCTGNATGTGAAAGGGNACTGNTGGGAGGATTGGATTT
  GTGAAGAACTGAAGAAATG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006541 unedited
  AAAAACCTTTTTTTTTTAATAATTTGAATTGTTTATTGCATTCTATTTTTGGTGGGGAAA
  AAAATGTAACATACATTTATTTAGCACGACATTGTGAAATACACAAAACATGTAACTGAG
  AAAGCAGGAATTTTCTATTCCTAGTCCATTTCTGAGGACTAAATCATGAACTGCTCCCAT
  TGTAATTAAATATTTCTTACAATAGTTGGGCACCAAGTTTAAGATTTATTAATTTTCTCC
  TCTCAGTATAGGCAGCAATTCACCATTTTCTTTCAGTTCCTTCACAATATCCAATCCTCC
  CACCAGCTCCCCTTTCACATACAGCTGAGGGTATGTTGGCCAATTTGAGTAAGCTTTTAA
  TCCTTGCCGAACTTCTTCATCCTCCAATATATCGAATGTTTCATATTCAACACCAGTACT
  ATTTAGTATTTCCAGAATTTGTTTGCTGAATCCACATTTTGCTTCCTGTTTGTTTCCTTT
  CATAAAGAGCATCACAGAAGCTTTATTTGTCAGCACTTTGAGCCTTTCCTCTAATTTGGG
  AGCTTTGGGACAAATTGTATCTAGTTCTTCAGATGCTTCTAGCTCCTTAATTATATCAAG
  TCCTCCTATGAGCTCTCCAGAAACATAGAGCTGAGGATAGGTAGGCCAACTGGAATANNG
  CTTGAGTCCCTGTCGAACCTCTTCATCTGAGAAGAATCAAAACTGCTAAACTGAATATTA
  TGTTTGTGAAGAATTTTCACATCTGCCTGCTGAAAACACAGCGTGGGTCTTGGAGGAGTT
  CCTTTCATAACAGCATGCAGGGGGCAGCATGAGTCATTTCCTTCAGCGAAAGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006541
• ORF Size: 1008 bp
• Insert Size: 1250
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006541.1, NP_006532.1
• RefSeq Size: 1942
• RefSeq ORF: 1008
• Locus ID: 10539
• Domains: thiored
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
  Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.