TXNL2 (GLRX3) (NM_006541) Human Untagged Clone

CAT#: SC321058

GLRX3 (untagged)-Human glutaredoxin 3 (GLRX3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GLRX3
• Synonyms: GLRX4; GRX3; GRX4; PICOT; TXNL2; TXNL3
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006541.2 GCTTCTGTCTGGCGGCGGCAGCATGGCGGCGGGGGCGGCTGAGGCAGCTGTAGCGGCCGT
  GGAGGAGGTCGGCTCAGCCGGGCAGTTTGAGGAGCTGCTGCGCCTCAAAGCCAAGTCCCT
  CCTTGTGGTCCATTTCTGGGCACCATGGGCTCCACAGTGTGCACAGATGAACGAAGTTAT
  GGCAGAGTTAGCTAAAGAACTCCCTCAAGTTTCATTTGTGAAGTTGGAAGCTGAAGGTGT
  TCCTGAAGTATCTGAAAAATATGAAATTAGCTCTGTTCCCACTTTTCTGTTTTTCAAGAA
  TTCTCAGAAAATCGACCGATTAGATGGTGCACATGCCCCAGAGTTGACCAAAAAAGTTCA
  GCGACATGCATCTAGTGGCTCCTTCCTACCCAGCGCTAATGAACATCTTAAAGAAGATCT
  CAACCTTCGCTTGAAGAAATTGACTCATGCTGCCCCCTGCATGCTGTTTATGAAAGGAAC
  TCCTCAAGAACCACGCTGTGGTTTCAGCAAGCAGATGGTGGAAATTCTTCACAAACATAA
  TATTCAGTTTAGCAGTTTTGATATCTTCTCAGATGAAGAGGTTCGACAGGGACTCAAAGC
  CTATTCCAGTTGGCCTACCTATCCTCAGCTCTATGTTTCTGGAGAGCTCATAGGAGGACT
  TGATATAATTAAGGAGCTAGAAGCATCTGAAGAACTAGATACAATTTGTCCCAAAGCTCC
  CAAATTAGAGGAAAGGCTCAAAGTGCTGACAAATAAAGCTTCTGTGATGCTCTTTATGAA
  AGGAAACAAACAGGAAGCAAAATGTGGATTCAGCAAACAAATTCTGGAAATACTAAATAG
  TACTGGTGTTGAATATGAAACATTCGATATATTGGAGGATGAAGAAGTTCGGCAAGGATT
  AAAAGCTTACTCAAATTGGCCAACATACCCTCAGCTGTATGTGAAAGGGGAGCTGGTGGG
  AGGATTGGATATTGTGAAGGAACTGAAAGAAAATGGTGAATTGCTGCCTATACTGAGAGG
  AGAAAATTAATAAATCTTAAACTTGGTGCCCAACTATTGTAAGAAATATTTAATTACATT
  GGGAGCAGTTCATGATTTAGTCCTCAGAAATGGACTAGGAATAGAAAATTCCTGCTTTCT
  CAGTTACATGTTTTGTGTATTTCACAATGTCGTGCTAAATAAATGTATGTTACATTTTTT
  TCCCACCAAAAATAGAATGCAATAAACATCTTCAAATTATTAACGAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006541.2 unedited
  CGACCACTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGGCCATTACGGCCGGGGGC
  TTCTGTCTGGCGGCGGCAGCATGGCGGCGGGGGCGGCTGAGGCAGCTGTAGCGGCCGTGG
  AGGAGGTCGGCTCAGCCGGGCAGTTTGAGGAGCTGCTGCGCCTCAAAGCCAAGTCCCTCC
  TTGTGGTCCATTTCTGGGCACCATGGGCTCCACAGTGTGCACAGATGAACGAAGTTATGG
  CAGAGTTAGCTAAAGAACTCCCTCAAGTTTCATTTGTGAAGTTGGAAGCTGAAGGTGTTC
  CTGAAGTATCTGAAAAATATGAAATTAGCTCTGTTCCCACTTTTCTGTTTTTCAAGAATT
  CTCAGAAAATCGACCGATTAGATGGTGCACATGCCCCAGAGTTGACCAAAAAAGTTCAGC
  GACATGCATCTAGTGGCTCCTTCCTACCCAGCGCTAATGAACATCTTAAAGAAGATCTCA
  ACCTTCGCTTGAAGAAATTGACTCATGCTGCCCCCTGCATGCTGTTTATGAAAGGAACTC
  CTCAAGAACCACGCTGTGGTTTCAGCAAGCAGATGGTGGAAATTCTTCACAAACATAATA
  TTCAGTTTAGCAGTTTTGATATCTTCTCAGATGAAGAGGTTCGACAGGGACTCAAAGCCT
  ATTCCAGTTGGCCTACCTATCCTCAGCTCTATGTTTCTGGAGAGCTCATAGGAGGACTTG
  ATATAATTAAAGAGCTAGAAGCATCTGAAGAACTAGATACAATTTGTCCCAAGCTCCCAA
  ATTAGAGGAAAAGCTCAAAGTGCTGACAAATAAAGCTTCTGTGATGCTCTTATGAAAGAA
  ACAAAACAGGAGCAAAATGTGGATTCAGCAAACAAATCTGAAATACTAAATAGTACTGTG
  TTGATATGAAACATTCGATATTATTGGAGGATGAAAAAAGTTC
• Restriction Sites: Please inquire
• ACCN: NM_006541
• ORF Size: 1008 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006541.2, NP_006532.2
• RefSeq Size: 1275
• RefSeq ORF: 1008
• Locus ID: 10539
• Domains: thiored
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
  Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.