SV2B (NM_014848) Human Untagged Clone

CAT#: SC108749

SV2B (untagged)-Human synaptic vesicle glycoprotein 2B (SV2B), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SV2B
• Synonyms: HsT19680
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_014848, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGATGACTACAAGTATCAGGACAATTATGGGGGCTATGCTCCCAGTGATGGCTATTACCGCGGCAATG
  AGTCCAACCCAGAAGAAGATGCACAGAGTGATGTCACCGAAGGCCATGATGAGGAAGACGAGATCTATGA
  GGGCGAGTACCAGGGTATCCCTCACCCAGATGATGTCAAGGCCAAGCAGGCCAAGATGGCGCCCTCCAGA
  ATGGACAGCCTTCGGGGCCAGACAGACCTGATGGCTGAGAGGCTGGAAGATGAGGAGCAGTTGGCCCACC
  AGTACGAGACCATCATGGATGAGTGTGGCCATGGCCGCTTCCAGTGGATCCTCTTTTTCGTCTTGGGTTT
  GGCCCTGATGGCCGATGGGGTGGAAGTGTTCGTGGTGAGTTTTGCCCTGCCCAGTGCAGAGAAGGACATG
  TGTCTGTCCAGTTCCAAAAAAGGAATGCTAGGGATGATAGTCTACTTGGGAATGATGGCGGGCGCCTTCA
  TCCTGGGAGGCCTGGCTGATAAGCTGGGAAGGAAGCGAGTCCTCAGCATGTCTCTGGCCGTCAATGCCTC
  CTTCGCCTCCCTCTCTTCCTTCGTGCAGGGATATGGAGCCTTCCTCTTCTGCCGACTCATCTCAGGCATC
  GGTATTGGGGGTGCTCTACCGATTGTTTTTGCCTATTTTTCTGAATTCTTGTCTCGGGAGAAGCGAGGAG
  AACACCTCAGTTGGCTGGGCATCTTCTGGATGACTGGGGGCCTGTACGCATCTGCCATGGCCTGGAGCAT
  CATCCCACACTATGGCTGGGGCTTCAGCATGGGGACCAATTACCACTTCCATAGCTGGAGAGTGTTTGTC
  ATCGTCTGTGCTCTGCCCTGCACCGTGTCCATGGTGGCCCTGAAGTTCATGCCAGAGAGCCCAAGGTTTC
  TGCTAGAGATGGGCAAACATGATGAAGCCTGGATGATTCTCAAGCAAGTCCATGACACCAACATGAGAGC
  TAAGGGGACCCCAGAGAAAGTGTTCACGGTTTCCAACATCAAAACTCCCAAGCAAATGGATGAATTCATT
  GAGATCCAAAGTTCAACAGGAACCTGGTACCAGCGCTGGCTGGTCAGATTCAAGACCATTTTCAAGCAGG
  TCTGGGATAATGCCCTGTACTGTGTGATGGGGCCCTACAGAATGAATACACTGATTCTGGCCGTGGTTTG
  GTTTGCCATGGCATTCAGTTACTATGGACTGACAGTTTGGTTTCCTGATATGATCCGCTATTTTCAAGAT
  GAAGAATACAAGTCTAAAATGAAGGTGTTTTTTGGTGAGCATGTGTACGGCGCCACAATCAACTTCACGA
  TGGAAAATCAGATCCACCAACATGGGAAACTTGTGAATGATAAGTTCACAAGAATGTACTTTAAACATGT
  ACTCTTTGAGGACACATTCTTTGACGAGTGCTATTTTGAAGACGTAACATCAACAGATACCTACTTCAAA
  AATTGTACCATTGAATCAACCATCTTTTACAACACAGACCTCTACGAGCACAAGTTCATCAACTGTCGGT
  TTATCAACTCCACCTTCCTGGAGCAGAAGGAGGGCTGCCACATGGACTTGGAGCAAGATAATGACTTCCT
  GATTTACCTCGTCAGCTTCCTGGGCAGCCTGTCTGTCTTACCCGGGAACATCATTTCTGCCCTGCTCATG
  GATAGAATTGGAAGGCTCAAGATGATTGGTGGCTCCATGCTAATCTCTGCAGTCTGCTGCTTCTTCCTGT
  TTTTTGGCAACAGTGAGTCTGCAATGATCGGCTGGCAGTGCCTGTTCTGTGGGACAAGCATTGCAGCCTG
  GAATGCTCTGGATGTGATCACAGTGGAGCTGTATCCCACCAACCAGAGAGCAACAGCCTTCGGCATTCTC
  AATGGATTATGCAAATTTGGCGCCATCCTGGGAAACACCATCTTTGCTTCTTTTGTTGGGATAACCAAAG
  TGGTCCCCATCCTTCTGGCTGCTGCTTCTCTGGTTGGGGGTGGCCTGATTGCCCTTCGACTGCCAGAGAC
  TCGAGAACAGGTCCTGATGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014848 unedited
  CAGAATTTTGTAATACGACTCACTTATAGGGCGGCCGCGAATTCGCACGAGGAAATAGCC
  CAAACCTCTACCACAGAGCGAGGGATATAGCTCAAGGGGCAACCAGGCAGTCGCAGAACC
  AAGGAATGGATGACTACAAGTATCAGGACAATTATGGGGGCTATGCTCCCAGTGATGGCT
  ATTACCGCGGCAATGAGTCCAACCCAGAAGAAGATGCACAGAGTGATGTCACCGAAGGCC
  ATGATGAGGAAGACGAGATCTATGAGGGCGAGTACCAGGGTATCCCTCACCCAGATGATG
  TCAAGGCCAAGCAGGCCAAGATGGCGCCCTCCAGAATGGACAGCCTTCGGGGCCAGACAG
  ACCTGATGGCTGAGAGGCTGGAAGATGAGGAGCAGTTGGCCCACCAGTACGAGACCATCA
  TGGATGAGTGTGGCCATGGCCGCTTCCAGTGGATCCTCTTTTTCGTCTTGGGTTTGGCCC
  TGATGGCCGATGGGGTGGAAGTGTTCGTGGTGAGTTTTGCCCTGCCCAGTGCAGAGAAGG
  ACATGTGTCTGTCCAGTTCCAAAAAAGGAATGCTAGGGATGATAGTCTACTTGGGAATGA
  TGGCGGGCGCCTTCATCCTGNGAGGCCTGGCTGATAAGCTGGGAAGGAAGCGAGTCCTCA
  GCATGTCTCTGGCCGTCAATGCCTCCTTCGCCTCCCTCTCTTCCTTCGTGCAGGGATATG
  GAGCCTTCCTCTTCTGCCGACTCATCTCANGCATCGGTATTGGNNGGTGCTCTACCGATT
  GTTTTTGCCTATNTTTCTGAATTCTTGTCTCGGGAGAAGCGAGGAGACACCTCAGNTGGC
  TGGGCATCTTCTGGATGACTGGGGGCCTGTACGCATCTGCCATGGCCTGNAGCATCATCC
  ACACTATGGCTGGNGCTTAGCATGGGGACCAATACACTTCTACNTGGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014848 unedited
  TTTTAGCTTTGGACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTT
  TTTCACTAATTATTTTTAATAAAACAAAAAATCAAAAATCAGCATCAGGAGATGACACAA
  TACAGTTGAGACTATGGAAAGCAACTATTTCCAAGCTGGGCATCATAAAATACATCATCA
  AGAACTGTGAACAGATTTGCTAAACAAAGGAAAGCCTCATCCCTTTAACCCTCCACAGCC
  GACATCGGGAGTCTCTTGGGGTAAAACATGAAGTGAAAAAAAAGTGGATGGCCAAAATGC
  TGTACATTGTCCCCCAGTGACCTGCCACAGAGACTATTTTTAAAGACGCATTTATCTCAG
  CAGGAGTGACGGCATTTAAAAAGTAGCCCGGTACTCAGGCTAGACAATCCTGCAAAAGTC
  TGCAAAGCTTGGCTGCACCCTTTACAAAGACCTGAGTGATGGATGAAATGGGAATTGCCC
  TTGATTGGCTAGGTGGCTGGTTTAAAGAGCCATAAAGATAATGCAGAAGTGAGATCTTGG
  AAACCAAATGGAGTTAGCCCCCAAATTATTGCAGCCACCCCAGCACTCCAATGTTAATCC
  AATTTTAAATTTACAAGATCCATCTTAACTAGAAATGCAGGCTCTAACTGTCCTGCAAGT
  TTTTTAAGTGGTAGCTGCTCAATGAATTGTATTATCCCATTAAAGAATAATGTTTTAGAT
  GTGGTAATCCCAGACTCACACAATTCTCTTTTATGAACCTAGCCACTGTATTCATATGGA
  AAGTAAATTACAGCTATATTACATCGAGCCTTTCANATTGACAGAGCATTAATGGTAGTA
  CTCCTATAAACACTGAGAGAAGATTATACCCAGTGTTATATATATTTGAAGGAATAGGNT
  GTCCAGTCAGACCAATAGTCTTCTCTCCCTGACAGAAAAAGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014848
• ORF Size: 11361 bp
• Insert Size: 5700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_014848.1, NP_055663.1
• RefSeq Size: 11361
• RefSeq ORF: 11361
• Locus ID: 9899
• Domains: sugar_tr
• Protein Families: Secreted Protein, Transmembrane
• Protein Pathways: ECM-receptor interaction
• Gene Summary: This gene encodes a member of the synaptic vesicle proteins 2 (SV2) family and major facilitator superfamily of proteins. This protein and other members of the family are localized to synaptic vesicles and may function in the regulation of vesicle trafficking and exocytosis. Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons, and that this protein may be important for the integrity of the glomerular filtration barrier. This gene shows reduced expression in areas of synaptic loss in the hippocampus of human temporal lobe epilepsy patients. [provided by RefSeq, Sep 2016]
  Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.