SERPINB1 (NM_030666) Human Untagged Clone

CAT#: SC109680

SERPINB1 (untagged)-Human serpin peptidase inhibitor, clade B (ovalbumin), member 1 (SERPINB1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SERPINB1
• Synonyms: EI; ELANH2; HEL-S-27; HEL57; LEI; M/NEI; MNEI; PI-2; PI2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_030666 edited
  GAATTCGGCACGAGGGGGAGCTCGGACTCCTACGCAGTCACCGGGAAGGGCCGCCGCCCC
  GCCCGCGGCTGCTGGCCCGGGTGACACTTCCGCCTGCTATAAGAGCAGCGGCCCTCGGTG
  CCTCCTTCCTGACCTCGCACCCAGCTCGGAGCCCGGAGCGTGCCTCGGCGGCCTGTCGGT
  TTTCACCATGGAGCAGCTGAGCTCAGCAAACACCCGCTTCGCCTTGGACCTGTTCCTGGC
  GTTGAGTGAGAACAATCCGGCTGGAAACATCTTCATCTCTCCCTTCAGCATTTCATCTGC
  TATGGCCATGGTTTTTCTGGGGACCAGAGGTAACACGGCAGCACAGCTGTCCAAGACTTT
  CCATTTCAACACGGTTGAAGAGGTTCATTCAAGATTCCAGAGTCTGAATGCTGATATCAA
  CAAACGTGGAGCGTCTTATATTCTGAAACTTGCTAATAGATTATATGGAGAGAAAACTTA
  CAATTTCCTTCCTGAGTTCTTGGTTTCGACTCAGAAAACATATGGTGCTGACCTGGCCAG
  TGTGGATTTTCAGCATGCCTCTGAAGATGCAAGGAAGACCATAAACCAGTGGGTCAAAGG
  ACAGACAGAAGGAAAAATTCCGGAACTGTTGGCTTCGGGCATGGTTGATAACATGACCAA
  ACTTGTGCTAGTAAATGCCATCTATTTCAAGGGAAACTGGAAGGATAAATTCATGAAAGA
  AGCCACGACGAATGCACCATTCAGATTGAATAAGAAAGACAGAAAAACTGTGAAAATGAT
  GTATCAGAAGAAAAAATTTGCATATGGCTACATCGAGGACCTTAAGTGCCGTGTGCTGGA
  ACTGCCTTACCAAGGCGAGGAGCTCAGCATGGTCATCCTGCTGCCGGATGACATTGAGGA
  CGAGTCCACGGGCCTGAAGAAGATTGAGGAACAGTTGACTTTGGAAAAGTTGCATGAGTG
  GACTAAACCTGAGAATCTCGATTTCATTGAAGTTAATGTCAGCTTGCCCAGGTTCAAACT
  GGAAGAGAGTTACACTCTCAACTCCGACCTCGCCCGCCTAGGTGTGCAGGATCTCTTTAA
  CAGTAGCAAGGCTGATCTGTCTGGCATGTCAGGAGCCAGAGATATTTTTATATCAAAAAT
  TGTCCACAAGTCATTTGTGGAAGTGAATGAAGAGGGAACAGAGGCGGCAGCTGCCACAGC
  AGGCATCGCAACTTTCTGCATGTTGATGCCCGAAGAAAATTTCACTGCCGACCATCCATT
  CCTTTTCTTTATTCGGCATAATTCCTCAGGTAGCATCCTATTCTTGGGGAGATTTTCTTC
  CCCTTAGAAGAAAGAGACTGTAGCAATACAAAAATCAAGCTTAGTGCTTTATTACCTGAG
  TTTTTAATAGAGCCAATATGTCTTATATCTTTACCAATAAAACCACTGTCCAGAAACAAG
  TCTTTCATTTTCTTTGTAAGTTTGGCTCTGTTGGCTGTTTACACCCATGAATTTTGGCAT
  GGGTATCTATTTTTCTTTTTTACATTGAAAAAAATCCAGTGGTTGCTTTTGAATGCATCA
  AGTAAAGAAGAAGAAAAGAATACATCCGATGCGTAGATTCTTGACCATGTAGTAATCTAT
  AAAATTGCTATATCCTCCTGATAGCCATGGGAAAACATGATAAGATGGTCATTTATTTTG
  CAGTTAGAATTTTGGAAGCCACAAAATAGACAGACACCCTGACTGTTGAAGGGAGGTTTA
  AAAACAGATATTCAATTGAAATGTAAGAGAGCACCCCAATTGAGAGCCCAGGTTACGAAG
  ACAAGCTTGCCTCGCCTGACTTTTCTGTCCCTTGTTCTGCAGGATTAGTATTCTGTTACA
  GACCTCTAGTTTTTAGACTCTTCAATTAAAGGGCCAATGGTTATAACCTGCATTCCCTTT
  TTTGTTCTTCTTTATGTATAATATATAGTTCATGTGGCGCTGCATGAAATCAAGAAGTGG
  GTGTCTTAGGATAAAAGATACCAAGAGTCTACAAAAATAACCATGTAGTAAGATAAACTG
  CTGAACAAGGTTTTACTGTTAGCCACCTTCTCAGXXXXXXXXXXXXXXXXXXXXXXXXXX
  XXXXXXXAGCTCACCGCAACCTTTGCCTCCTGGGTTCAAGTGATTCTCTTGCTTCAGCCT
  CCTGAGTAGCTGGGATTATAGGCNTGCACCNCTAGGCCTGGCTAATTTTTGTATTTTTAG
  TAGAGATGGGGTTTTTCCATGTTGGCCNGGCTGGTCCCGAACTCCTGACCTCAGGTGATC
  CGCGCACCTCAGCCTCCCAAANTGCTGGGATTACAGGCATGAGCTACCATGCCTGGCCTT
  CTCATGTGTTTTCTGATTAAGGCTCTTGACTTCCAAGGCTGTGTGGGGAGATGGGGTGGG
  GGCTCTTGGACTGATATAAAACTTTGTCAAATGTAGTTCTTTGAATGGAGCCNGAAACGC
  CGCATATTCTTGCTCCCACAAGGATAGNGGCATCXXXXXXXXXXXAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_030666 unedited
  AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGGAGCTCGGACTCCTACG
  CAGTCACCGGGAAGGGCCGCCGCCCCGCCCGCGGCTGCTGGCCCGGGTGACACTTCCGCC
  TGCTATAAGAGCAGCGGCCCTCGGTGCCTCCTTCCTGACCTCGCACCCAGCTCGGAGCCC
  GGAGCGTGCCTCGGCGGCCTGTCGGTTTTCACCATGGAGCAGCTGAGCTCAGCAAACACC
  CGCTTCGCCTTGGACCTGTTCCTGGCGTTGAGTGAGAACAATCCGGCTGGAAACATCTTC
  ATCTCTCCCTTCAGCATTTCATCTGCTATGGCCATGGTTTTTCTGGGGACCAGAGGTAAC
  ACGGCAGCACAGCTGTCCAAGACTTTCCATTTCAACACGGTTGAAGAGGTTCATTCAAGA
  TTCCAGAGTCTGAATGCTGATATCAACAAACGTGGAGCGTCTTATATTCTGAAACTTGCT
  AATAGATTATATGGAGAGAAAACTTACAATTTCCTTCCTGAGTTCTTGGTTTCGACTCAG
  AAAACATATGGTGCTGACCTGGCCAGTGTGGATTTTCAGCATGCCTCTGAAGATGCAAGG
  AAGACCATAAACCAGTGGGTCAAAGGACAGACAGAAGGAAAAATTCCGGAACTGTTGGCT
  TCGGGCATGGTTGATAACATGACCAAACTTGTGCTAGTAAATGCCATCTATTTCAAGGGA
  AACTGGGAGGATANATTCATGAAAGAAGCCACGACGAATGCACCATTCAGATTTGATAAG
  AAAGACAGANNAACTGTGAAAATGATGTATCAGAAGAAAAAATTGCATATGGCTACATCG
  AGGACCTTAGTGCCGTGTGCTGGGACTGCCTTACCAGGGCGAGAGCTCAGCATGGTCATC
  CTGCTGCCGGAGACANTTGAGACGAGTCACGGCCTGAAGAAAATGAGAAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_030666
• Insert Size: 2790 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_030666.2, NP_109591.1
• RefSeq Size: 1310 bp
• RefSeq ORF: 1140 bp
• Locus ID: 1992
• Cytogenetics: 6p25.2
• Domains: SERPIN
• Protein Families: Druggable Genome
• Gene Summary: 'The protein encoded by this gene is a member of the serpin family of proteinase inhibitors. Members of this family maintain homeostasis by neutralizing overexpressed proteinase activity through their function as suicide substrates. This protein inhibits the neutrophil-derived proteinases neutrophil elastase, cathepsin G, and proteinase-3 and thus protects tissues from damage at inflammatory sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]'
  Transcript Variant: This variant (1) encodes the functional protein.