DUSP10 (NM_007207) Human Untagged Clone

CAT#: SC111766

DUSP10 (untagged)-Human dual specificity phosphatase 10 (DUSP10), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DUSP10
• Synonyms: MKP-5; MKP5
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111766 sequence for NM_007207 edited (data generated by NextGen Sequencing)
  ATGCCTCCGTCTCCTTTAGACGACAGGGTAGTAGTGGCACTATCTAGGCCCGTCCGACCT
  CAGGATCTCAACCTTTGTTTAGACTCTAGTTACCTTGGCTCTGCCAACCCAGGCAGTAAC
  AGCCACCCTCCTGTCATCGCCACCACCGTTGTGTCCCTCAAGGCTGCGAATCTGACGTAT
  ATGCCCTCATCCAGCGGCTCTGCCCGCTCGCTGAATTGTGGATGCAGCAGTGCCAGCTGC
  TGCACTGTGGCAACCTACGACAAGGACAATCAGGCCCAAACCCAAGCCATTGCCGCTGGC
  ACCACCACCACTGCCATCGGAACCTCTACCACCTGCCCTGCTAACCAGATGGTCAACAAT
  AATGAGAATACAGGCTCTCTAAGTCCATCAAGTGGGGTGGGCAGCCCTGTGTCAGGGACC
  CCCAAGCAGCTAGCCAGCATCAAAATAATCTACCCCAATGACTTGGCAAAGAAGATGACC
  AAATGCAGCAAGAGTCACCTGCCGAGTCAGGGCCCTGTCATCATTGACTGCAGGCCCTTC
  ATGGAGTACAACAAGAGTCACATCCAAGGAGCTGTCCACATTAACTGTGCCGATAAGATC
  AGCCGGCGGAGACTGCAGCAGGGCAAGATCACTGTCCTAGACTTGATTTCCTGTAGGGAA
  GGCAAGGACTCTTTCAAGAGGATCTTTTCCAAAGAAATTATAGTTTATGATGAGAATACC
  AATGAACCAAGCCGAGTGATGCCCTCCCAGCCACTTCACATAGTCCTCGAGTCCCTGAAG
  AGAGAAGGCAAAGAACCTCTGGTGTTGAAAGGTGGACTTAGTAGTTTTAAGCAGAACCAT
  GAAAACCTCTGTGACAACTCCCTCCAGCTCCAAGAGTGCCGGGAGGTGGGGGGCGGCGCA
  TCCGCGGCCTCGAGCTTGCTACCTCAGCCCATCCCCACCACCCCTGACATCGAGAACGCT
  GAGCTCACCCCCATCTTGCCCTTCCTGTTCCTTGGCAATGAGCAGGATGCTCAGGACCTG
  GACACCATGCAGCGGCTGAACATCGGCTACGTCATCAACGTCACCACTCATCTTCCCCTC
  TACCACTATGAGAAAGGCCTGTTCAACTACAAGCGGCTGCCAGCCACTGACAGCAACAAG
  CAGAACCTGCGGCAGTACTTTGAAGAGGCTTTTGAGTTCATTGAGGAAGCTCACCAGTGT
  GGGAAGGGGCTTCTCATCCACTGCCAGGCTGGGGTGTCCCGCTCCGCCACCATCGTCATC
  GCTTACTTGATGAAGCACACTCGGATGACCATGACTGATGCTTATAAATTTGTCAAAGGC
  AAACGACCAATTATCTCCCCAAACCTTAACTTCATGGGGCAGTTGCTAGAGTTCGAGGAA
  GACCTAAACAACGGTGTGACACCGAGAATCCTTACACCAAAGCTGATGGGCGTGGAGACG
  GTTGTGTGA
  
  Clone variation with respect to NM_007207.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007207 unedited
  GTTAGATTTTATACACTATTAGGCGGCCGCGATTCGCCGAGGACAATGAACCGATGATGG
  GGGCTGAATGTGCGAGTCCATAGCTGAAGAGGAGCGCCAGATGGTGGAGGAATACACTTA
  TTTATGAAACTGTCTTGAGTTCTTCTTGAATTGCCAGTTTTCAGCCTCCTCATGCCTCCG
  TCTCCTTTAGACGACAGGGTAGTAGTGGCACTATCTAGGCCCGTCCGACCTCAGGATCTC
  AACCTTTGTTTAGACTCTAGTTACCTTGGCTCTGCCAACCCAGGCAGTAACAGCCACCCT
  CCTGTCATCGCCACCACCGTTGTGTCCCTCAAGGCTGCGAATCTGACGTATATGCCCTCA
  TCCAGCGGCTCTGCCCGCTCGCTGAATTGTGGATGCAGCAGTGCCAGCTGCTGCACTGTG
  GCAACCTACGACAAGGACAATCAGGCCCAAACCCAAGCCATTGCCGCTGGCACCACCACC
  ACTGCCATCGGAACCTCTACCACCTGCCCTGCTAACCAGATGGTCAACAATAATGAGAAT
  ACAGGCTCTCTAAGTCCATCAAGTGGGGTGGGCAGCCCTGTGTCAGGGACCCCCAAGCAG
  CTAGCCAGCATCAAAATAATCTACCCCAATGACTTGGCAAAGAAGATGACCAAATGCAGC
  AAGAGTCACCTGCCGAGTCANGGCCCTGTCATCATTGACTGCAGGCCCTTCATGGAGTAC
  AACAAGAGTCACATCCAAGGAGCTGTCCACATTAACTGTGCCGNATAGATCAGCCGGCGG
  AGACTGCAGCAGGGCAAGATCACTGTCCTAGACTTGATTTCCTGTAGGGAAAGGCAGGAC
  TCTTTCAAGAGATCTTTTCAAAGAAATTATAGTTATGATGAGATACCCATGACCAAGCCG
  ATGATGCCCTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_007207 unedited
  TCTATGGACCGCGGCCCGCATTTCTAAAGTCGAGTTTTTTTTTTTTTTTTTTGCGAAAAA
  ATTTTTAAATAAATTTTTTTTTCTTACATTCTGATATACATATGTAACAAGGTTTATGGC
  ACTGTAACCAGAATCAAATCAGAAAAAAAAAAAAAAAGGAAAAAGGTGGGAAGGAAAGTA
  TTTGATATATTGTTGAATTCCTTTCTATCTCCAAGCTGGCAAATTTGCACTATTTGTCTA
  TCATTCAGCTGCCAGCTCTAACTTGTTTGCACACTTAAAACATCATATTATTGCACAAGA
  AGCCAGTGAAGGCATATAATGGTCAGTTCCTCACTATTTCAAAAAAAATCTCTTAAACCC
  AGAGAAGGAAAAAAAAAAAAAAAATCCAGAGCATGAAACACACAAAATCAAAGGTATCCT
  TTTTCTCCTTAAAGAATGCCTGAAGGATTCTTAAACCACTTAAGCTGCCCTGATCTTCTC
  TTTGCACCAGTGAGCACAACAGGGCTTGGTTTGGTTGGGTTTTTGTTTTCTGTGTGGACA
  GCCCAGGTTGATCCCAGGCCTTGGAGATTCAATGTCTTTTCTATTTACTTTTGGTTCTTT
  TTAATTGGTTTAAAGTGTGTAGTATCTTCGGTCTATGAACCTGCACAGACTATTTAGTCA
  TAAACTCTACAAATAGCTTAAAAGGAAAAGGGGGAGAAACAAGTTGTATTATATTTTTAT
  TGTTGGCTTAAAAAATTACTTCTTTAACCTCCTTAATTTGNCAGTTTNGTGGGAAGTGAA
  TCTCAATGGCATCAAAAGCTATAGTCTTCCTACACTTGTTAANNATNAAGTGTTAAANNC
  AGTTTGTTCCATTTCACAACTTACTCCCCACCTCANNAAAAAAAGAAAGAAAAAACCCGA
  ACCCTCCTCCCTCCTCATGCCTCCTAATGGAGAGCAGCATCCTTTTCATTNCAGACATTG
  TNACACAACGTNNTCACGCCATAGCTTTGTTGAAGGATT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_007207
• ORF Size: 1449 bp
• Insert Size: 2750
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_007207.3, NP_009138.1
• RefSeq Size: 2619
• RefSeq ORF: 1449
• Locus ID: 11221
• Domains: DSPc, RHOD
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: MAPK signaling pathway
• Gene Summary: Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the functional protein.