DUSP10 (NM_007207) Human Untagged Clone

CAT#: SC322594

DUSP10 (untagged)-Human dual specificity phosphatase 10 (DUSP10), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DUSP10
• Synonyms: MKP-5; MKP5
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322594 TGGAGATCAATGAAGCCGAGTGAATGGGGGCTGAATGTGCGAGTCCATAGCTGAAGAGGA
  GCGCCAGATGGTGGAGGAATACACTTATTTATGAAACTGTCTTGAGTTCTTCTTGAATTG
  CCAGTTTTCAGCCTCCTCATGCCTCCGTCTCCTTTAGACGACAGGGTAGTAGTGGCACTA
  TCTAGGCCCGTCCGACCTCAGGATCTCAACCTTTGTTTAGACTCTAGTTACCTTGGCTCT
  GCCAACCCAGGCAGTAACAGCCACCCTCCTGTCATCGCCACCACCGTTGTGTCCCTCAAG
  GCTGCGAATCTGACGTATATGCCCTCATCCAGCGGCTCTGCCCGCTCGCTGAATTGTGGA
  TGCAGCAGTGCCAGCTGCTGCACTGTGGCAACCTACGACAAGGACAATCAGGCCCAAACC
  CAAGCCATTGCCGCTGGCACCACCACCACTGCCATCGGAACCTCTACCACCTGCCCTGCT
  AACCAGATGGTCAACAATAATGAGAATACAGGCTCTCTAAGTCCATCAAGTGGGGTGGGC
  AGCCCTGTGTCAGGGACCCCCAAGCAGCTAGCCAGCATCAAAATAATCTACCCCAATGAC
  TTGGCAAAGAAGATGACCAAATGCAGCAAGAGTCACCTGCCGAGTCAGGGCCCTGTCATC
  ATTGACTGCAGGCCCTTCATGGAGTACAACAAGAGTCACATCCAAGGAGCTGTCCACATT
  AACTGTGCCGATAAGATCAGCCGGCGGAGACTGCAGCAGGGCAAGATCACTGTCCTAGAC
  TTGATTTCCTGTAGGGAAGGCAAGGACTCTTTCAAGAGGATCTTTTCCAAAGAAATTATA
  GTTTATGATGAGAATACCAATGAACCAAGCCGAGTGATGCCCTCCCAGCCACTTCACATA
  GTCCTCGAGTCCCTGAAGAGAGAAGGCAAAGAACCTCTGGTGTTGAAAGGTGGACTTAGT
  AGTTTTAAGCAGAACCATGAAAACCTCTGTGACAACTCCCTCCAGCTCCAAGAGTGCCGG
  GAGGTGGGGGGCGGCGCATCCGCGGCCTCGAGCTTGCTACCTCAGCCCATCCCCACCACC
  CCTGACATCGAGAACGCTGAGCTCACCCCCATCTTGCCCTTCCTGTTCCTTGGCAATGAG
  CAGGATGCTCAGGACCTGGACACCATGCAGCGGCTGAACATCGGCTACGTCATCAACGTC
  ACCACTCATCTTCCCCTCTACCACTATGAGAAAGGCCTGTTCAACTACAAGCGGCTGCCA
  GCCACTGACAGCAACAAGCAGAACCTGCGGCAGTACTTTGAAGAGGCTTTTGAGTTCATT
  GAGGAAGCTCACCAGTGTGGGAAGGGGCTTCTCATCCACTGCCAGGCTGGGGTGTCCCGC
  TCCGCCACCATCGTCATCGCTTACTTGATGAAGCACACTCGGATGACCATGACTGATGCT
  TATAAATTTGTCAAAGGCAAACGACCAATTATCTCCCCAAACCTTAACTTCATGGGGCAG
  TTGCTAGAGTTCGAGGAAGACCTAAACAACGGTGTGACACCGAGAATCCTTACACCAAAG
  CTGATGGGCGTGGAGACGGTTGTGTGACAATGGTCTGGATGGAAAGGATTGCTGCTCTCC
  ATTAGGAGACAATGAGGAAGGAGGATGGATTCTGGTTTTTTTTCTTTCTTTTTTTTTTTG
  TAGTTGGGAGTAAGTTTGTGAATGGAAACAAACTTGTTTAAACACTTTATTTTTAACAAG
  TGTAAGAAGACTATAACTTTTGATGCCATTGAGATTCACCTCCCACAAACTGACAAATTA
  AGGAGGTTAAAGAAGTAATTTTTTTAAGCCAACAATAAAAATATAATACAACTTGTTTCT
  CCCCCTTTTCCTTTTAAGCTATTTGTAGAGTTTATGACTAAATAGTCTGTGCAGGTTCAT
  AGACCGAAGATACTACACACTTTAAACCAATTAAAAAGAACCAAAAGTAAATAGAAAAGA
  CATTGAATCACCAAGGCCTGGGATCAACCTGGGCTGTCCACACAGAAAACAAAAACCCAA
  CCAAACCAAGCCCTGTTGTGCTCACTGGTGCAAAGAGAAGATCAGGGCAGCTTAAGTGGT
  CTAAGAATCCTTCAGGCATTCTTTAAGGAGAAAAAGGATACCTTTGATTTTGTGTGTTTC
  ATGCTCTGGATTTTTTTTTTTTTTTCTTCTCTGGGTTTAAGAGATTTTTTTTGAAATAGT
  GAGGAACTGACCATTATATGCCTTCACTGGCTTCTTGTGCAATAATATGATGTTTTAAGT
  GTGCAAACAAGTTAGAGCTGGCAGCTGAATGATAGACAAATAGTGCAAATTTGCCAGCTT
  GGAGATAGAAAGGAATTCAACAATATATCAAATACTTTCCTTCCCACCTTTTTCCTTTTT
  TTTTTTTTTTTCTGATTTGATTCTGGTTACAGTGCCATAAACCTTGTTACATATGTATAT
  CAGAATGTAAGAAAAAAAAATTTATTTAAAAATATTTTTCGCAAAAAAAAAAAAAAATCT
  TGGTGTGTTTCTGTTGATTGTGTAAAAATTTATTTTCATTATATAAATGAAACTGGAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322594 unedited
  GACCATTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCC
  GGAATTCCCGGGATTGGAGATCAATGAAGCCGAGTGAATGGGGGCTGAATGTGCGAGTCC
  ATAGCTGAAGAGGAGCGCCAGATGGTGGAGGAATACACTTATTTATGAAACTGTCTTGAG
  TTCTTCTTGAATTGCCAGTTTTCAGCCTCCTCATGCCTCCGTCTCCTTTAGACGACAGGG
  TAGTAGTGGCACTATCTAGGCCCGTCCGACCTCAGGATCTCAACCTTTGTTTAGACTCTA
  GTTACCTTGGCTCTGCCAACCCAGGCAGTAACAGCCACCCTCCTGTCATCGCCACCACCG
  TTGTGTCCCTCAAGGCTGCGAATCTGACGTATATGCCCTCATCCAGCGGCTCTGCCCGCT
  CGCTGAATTGTGGATGCAGCAGTGCCAGCTGCTGCACTGTGGCAACCTACGACAAGGACA
  ATCAGGCCCAAACCCAAGCCATTGCCGCTGGCACCACCACCACTGCCATCGGAACCTCTA
  CCACCTGCCCTGCTAACCAGATGGTCAACAATAATGAGAATACAGGCTCTCTAAGTCCAT
  CAAGTGGGGTGGGCAGCCCTGTGTCAGGGACCCCCAAGCAGCTAGCCAGCATCAAAATAA
  TCTACCCCAATGACTTGGCAAAGAAGATGACCAAATGCAGCAAGAGTCACCTGCCGAGTC
  AGGCCCTGTCATCATTGACTGCAGGCCCTTCATGGAGTACAACAGAGTCACATCCAAGGA
  GCTGTCCACATTAACTGTGCCGATAGATCAGCGGCGGAGACTGCAGCAGGCAGATCACTG
  TCTAGACTTGATTCTGTAGGAGCAGACTCTTCAGAGATTCTTTCAGAAATTATAGTTATG
  ATGGAGAATAC
• Restriction Sites: Please inquire
• ACCN: NM_007207
• ORF Size: 1449 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_007207.3, NP_009138.1
• RefSeq Size: 2619
• RefSeq ORF: 1449
• Locus ID: 11221
• Domains: DSPc, RHOD
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: MAPK signaling pathway
• Gene Summary: Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the functional protein.