ATG4C (NM_178221) Human Untagged Clone

CAT#: SC111887

ATG4C (untagged)-Human ATG4 autophagy related 4 homolog C (S. cerevisiae) (ATG4C), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ATG4C
• Synonyms: APG4-C; APG4C; AUTL1; AUTL3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_178221, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGGCTACAGGAACAGATGAAGTTGACAAGCTAAAAACCAAATTTATATCTGCTTGGAACAACATGA
  AATATAGTTGGGTGTTGAAAACAAAGACGTATTTTAGTAGAAATTCTCCTGTATTATTGCTTGGAAAATG
  TTACCATTTTAAATATGAAGATGAAGATAAAACGTTACCTGCAGAGTCGGGATGTACAATAGAGGATCAC
  GTAATTGCAGGAAATGTAGAAGAATTTCGTAAAGATTTCATTTCTAGAATATGGCTGACCTACAGGGAAG
  AATTCCCTCAAATAGAAGGCTCAGCTTTGACAACAGACTGTGGGTGGGGCTGCACATTGAGAACTGGCCA
  GATGCTCTTGGCTCAAGGACTCATACTACACTTTCTTGGTAGAGCTTGGACCTGGCCTGATGCTTTGAAT
  ATTGAAAATTCAGACTCTGAATCATGGACTTCCCACACTGTCAAAAAATTTACTGCATCATTTGAAGCAT
  CACTTTCAGGGGAAAGAGAATTCAAAACCCCAACAATTTCTCTGAAGGAAACAATTGGGAAATATTCTGA
  TGATCATGAAATGCGAAATGAAGTTTATCATAGGAAAATCATCTCTTGGTTTGGTGATTCCCCCTTGGCT
  CTTTTTGGCTTACATCAACTAATAGAATATGGAAAGAAGTCTGGGAAAAAAGCAGGAGATTGGTATGGAC
  CAGCTGTGGTTGCTCACATTTTAAGAAAAGCAGTTGAAGAAGCAAGGCATCCTGATTTACAAGGAATAAC
  TATTTATGTTGCACAAGATTGTACAGTTTACAATTCTGATGTAATTGATAAACAGAGTGCTTCCATGACT
  TCTGATAATGCAGATGACAAAGCTGTTATTATTCTAGTTCCTGTTAGACTTGGTGGAGAAAGAACCAACA
  CCGACTACTTAGAATTTGTGAAGGGTATTTTAAGCCTGGAATATTGTGTGGGTATTATTGGTGGCAAACC
  TAAACAGTCATATTACTTTGCTGGATTTCAAGATGACAGTTTGATTTACATGGATCCTCATTACTGCCAA
  TCTTTTGTAGATGTCAGCATAAAGGATTTCCCTCTTGAGACATTCCACTGCCCTTCTCCCAAAAAGATGT
  CTTTTCGAAAAATGGATCCCAGCTGTACAATAGGATTTTACTGTCGAAATGTTCAGGACTTCAAACGAGC
  TTCTGAAGAAATCACCAAGATGCTGAAATTTTCTTCTAAGGAGAAATATCCCTTATTTACTTTTGTAAAT
  GGTCATTCCAGAGACTATGATTTTACATCTACTACAACCAATGAAGAAGACCTTTTTTCAGAGGATGAAA
  AGAAACAATTAAAAAGATTTAGCACGGAAGAGTTTGTCTTGCTTTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_178221 unedited
  TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCCGGGGTGCTCAAAGT
  ACCTGTAGCTGCGGCGCTGAGGTCGGAACGTCTGCGTGTGTGCGGGCTGGTTTTGTGGCG
  GCTGCTGCTAGAGCTGGAGCATTTGCCGGTCAGTATAAAAGATTAAACTCTACAGAAGAA
  TGCAATCAAGTGATGGCTTTTCCTTTAGAATTTGAATATGGAGGCTACAGGAACAGATGA
  AGTTGACAAGCTAAAAACCAAATTTATATCTGCTTGGAACAACATGAAATATAGTTGGGT
  GTTGAAAACAAAGACGTATTTTAGTAGAAATTCTCCTGTATTATTGCTTGGAAAATGTTA
  CCATTTTAAATATGAAGATGAAGATAAAACGTTACCTGCAGAGTCGGGATGTACAATAGA
  GGATCACGTAATTGCAGGAAATGTAGAAGAATTTCGTAAAGATTTCATTTCTAGAATATG
  GCTGACCTACAGGGAAGAATTCCCTCAAATAGAAGGCTCAGCTTTGACAACAGACTGTGG
  GTGGGGCTGCACATTGAGAACTGGCCAGATGCTCTTGGCTCAAGGACTCATACTACACTT
  TCTTGGTAGAGCTTGGACCTGGCCTGATGCTTTGAATATTGAAAATTCAGACTCTGAATC
  ATGGACTTCCCACACTGTCAAAAAATTTACTGCATCATTTGAAGCATCACTTTCAGGGGA
  AAGAGAATTCAAAACCCCAACAATTTCTCTGAAGGAAACAATTGGAAAATATTCTGATGA
  TCATGAAATGCGAAATGAAAGTTATCATAGGAAAATCATCTCTGGGTTGGTNGATTCCCC
  CTTGGCTCTTTTTGGGGCTACATNNCACTATAGATATGGNAAAAGAGTCTGGGAAAAAGC
  CAGANAATGGTATGGACANNCTGTGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_178221 unedited
  CTTCCCGGCCAGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTCA
  GGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTAGATTTCAGACTATTTATTTCAACTCAGTAAGTAATCTTCACTGAGAAA
  TGTCAAACCTGATTTTTCTCATCAGGTATACTAAAACAATCCGCCCACCCTCTCTTTCAG
  CTTTACATGCAACTCTAAACAAACAGGTTTTCTGATGGAAGAGATCAATGACTTTAGATG
  ATACACAATTTTATGTCTTTATAAGTCACGTTTCTACACTGAAACATGAAAGCTCCACTT
  AAAAAAATTAATATTGTTTTCAGAGCAATATATGCATTTATTATAAATGAACAGAATTCA
  TTTGAGACACTGATTTTTCAAATGAAAGGATTAAAATAATCCCAACATTAAAACCAAAAC
  AAAAGCATTTTATCTTCTCACATCTTTATTATGTATTTTATAATCCTAGCTCAAAAATCA
  CTCTTGTACTTTTAGATCACAAATTTGCCTTTAAGTAACACATAATACACTTAAGGCAGA
  TTTGCCTTACAGGTGCCTCAGCTTCTAACACCACTACACTGGCTTATATAAAAACAAAAA
  TCCATTGAAGAGAATCTAGTGCATCTTTCTTGGTTTTTTAACTTAAAACTGCTAATNAAT
  GAGTCCCTAAATTTCGCCCTGGATAGAACAACCTCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_178221
• ORF Size: 1377 bp
• Insert Size: 2800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_178221.1, NP_835739.1
• RefSeq Size: 1774
• RefSeq ORF: 1377
• Locus ID: 84938
• Protein Families: Protease
• Protein Pathways: Regulation of autophagy
• Gene Summary: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) uses a different splice site in the 5' UTR as compared to variant 1. Variants 1 and 2 encode the same protein.