SLC22A17 (NM_020372) Human Untagged Clone

CAT#: SC113106

SLC22A17 (untagged)-Human solute carrier family 22, member 17 (SLC22A17), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC22A17
• Synonyms: 24p3R; BOCT; BOIT; hBOIT; NGALR; NGALR2; NGALR3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_020372, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCTCGGACCCCATCTTCACGCTGGCGCCCCCGCTGCATTGCCACTACGGGGCCTTCCCCCCTAATG
  CCTCTGGCTGGGAGCAGCCTCCCAATGCCAGCGGCGTCAGCGTCGCCAGCGCTGCCCTAGCAGCCAGCGC
  CGCCAGCCGTGTCGCCACCAGTACCGACCCCTCGTGCAGCGGCTTCGCCCCGCCGGACTTCAACCATTGC
  CTCAAGGATTGGGACTATAATGGCCTTCCTGTGCTCACCACCAACGCCATCGGCCAGTGGGATCTGGTGT
  GTGACCTGGGCTGGCAGGTGATCCTGGAGCAGATCCTCTTCATCTTGGGCTTTGCCTCCGGCTACCTGTT
  CCTGGGTTACCCCGCAGACAGATTTGGCCGTCGCGGGATTGTGCTGCTGACCTTGGGGCTGGTGGGCCCC
  TGTGGAGTAGGAGGGGCTGCTGCAGGCTCCTCCACAGGCGTCATGGCCCTCCGATTCCTCTTGGGCTTTC
  TGCTTGCCGGTGTTGACCTGGGTGTCTACCTGATGCGCCTGGAGCTGTGCGACCCAACCCAGAGGCTTCG
  GGTGGCCCTGGCAGGGGAGTTGGTGGGGGTGGGAGGGCACTTCCTGTTCCTGGGCCTGGCCCTTGTCTCT
  AAGGATTGGCGATTCCTACAGCGAATGATCACCGCTCCCTGCATCCTCTTCCTGTTTTATGGCTGGCCTG
  GTTTGTTCCTGGAGTCCGCACGGTGGCTGATAGTGAAGCGGCAGATTGAGGAGGCTCAGTCTGTGCTGAG
  GATCCTGGCTGAGCGAAACCGGCCCCATGGGCAGATGCTGGGGGAGGAGGCCCAGGAGGCCCTGCAGGAC
  CTGGAGAATACCTGCCCTCTCCCTGCAACATCCTCCTTTTCCTTTGCTTCCCTCCTCAACTACCGCAACA
  TCTGGAAAAATCTGCTTATCCTGGGCTTCACCAACTTCATTGCCCATGCCATTCGCCACTGCTACCAGCC
  TGTGGGAGGAGGAGGGAGCCCATCGGACTTCTACCTGTGCTCTCTGCTGGCCAGCGGCACCGCAGCCCTG
  GCCTGTGTCTTCCTGGGGGTCACCGTGGACCGATTTGGCCGCCGGGGCATCCTTCTTCTCTCCATGACCC
  TTACCGGCATTGCTTCCCTGGTCCTGCTGGGCCTGTGGGATTGTGAGCATCCTATCTTCCCCACAGTGTG
  GGCTCAACAAGGGAACCCCAACAGAGATCTGAACGAGGCTGCCATCACCACTTTCTCTGTCCTTGGGCTC
  TTCTCCTCCCAAGCTGCCGCCATCCTCAGCACCCTCCTTGCTGCTGAGGTCATCCCCACCACTGTCCGGG
  GCCGTGGCCTGGGCCTGATCATGGCTCTAGGGGCGCTTGGAGGACTGAGCGGCCCGGCCCAGCGCCTCCA
  CATGGGCCATGGAGCCTTCCTGCAGCACGTGGTGCTGGCGGCCTGCGCCCTCCTCTGCATTCTCAGCATT
  ATGCTGCTGCCGGAGACCAAGCGCAAGCTCCTGCCCGAGGTGCTCCGGGACGGGGAGCTGTGTCGCCGGC
  CTTCCCTGCTGCGGCAGCCACCCCCTACCCGCTGTGACCACGTCCCGCTGCTTGCCACCCCCAACCCTGC
  CCTCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020372 unedited
  NGGGGTTCACATTTGTATACGACTCACTATAGGCGGCCGGATTCGCACGAGCCCACCTCC
  AACGGACAGGTCGGGACCCTCGGAGATGCGGTGCCCACGGAGCAGCTGCAGGGTGAGCGG
  GAGCGCGAGCGGGAGGGGGAGGGAGACGCGGGCGGCGACGGACTGGGCAGCAGCCTGTCG
  CTGGCCGTGCCCCCAGGCCCCCTCAGCTTTGAGGCGCTGCTCGCCCAGGTGGGGGCGCTG
  GGCGGCGGCCAGCAGCTGCAGCTCGGCCTCTGCTGCCTGCCGGTGCTCTTCGTGGCTCTG
  GGCATGGCCTCGGACCCCATCTTCACGCTGGCGCCCCCGCTGCATTGCCACTACGGGGCC
  TTCCCCCCTAATGCCTCTGGCTGGGAGCAGCCTCCCAATGCCAGCGGCGTCAGCGTCGCC
  AGCGCTGCCCTAGCAGCCAGCGCCGCCAGCCGTGTCGCCACCAGTACCGACCCCTCGTGC
  AGCGGCTTCGCCCCGCCGGACTTCAACCATTGCCTCAAGGATTGGGACTATAATGGCCTT
  CCTGTGCTCACCACCAACGCCATCGGCCAGTGGGATCTGGTGTGTGACCTGNGCTGGCAG
  GTGATCCTGGAGCAGATCCTCTTCATCTTGGGCTTTGCCTCCGGCTACCTGTTCCTGGGT
  TACCCCGCAGACAGATTTGGCCGTCGCGGGATTGTGCTGCTGACCTTGGGGCTGGTGGGC
  CCCTGTGGAGTANGANGGGCTGCTGCAGGCTCCTCCACAGGCGTCATGGCCCTCCGATTC
  CTCTTGGGCTNTCTGCTTGCCGGTGTTGACCTGGGTGTCTACCTGATGCGCCTGGAGCTG
  TGCGACCCACCCANAGGCTTCGGTGCCCTGCANNGGAANTGTGGGGGTTGGGAGGCACTT
  CTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020372 unedited
  CACTGTGGGGAGGGGCTCACAGGGTATGCACACCCGGGGATCTGTTTCAGGTAAACAGCT
  AGTGACCGCGGCGCGCAATCTAGGAGTCGAGTTTTTTTTTTTCTTTTTTTTTTTTTTGTT
  TTTTTTTTTTTTTTTTTTTTTTTTTGATTGCCAAATGTCTTTTTTGAAACAGAATGATAG
  AGCAAGAAATAATGGGGTCTGGGGGGATGTCTTTGGGCCCAGGATGGAGCCCAAACCCAG
  TGGTTACAGGGGGGAGCTTTTTCCCTGTCCCCTGACTTTGGCCAAGGAAGGGAATGCAAA
  ACACCCGGGGGGAGGCAGGGGGGGGACCGCCCTTTGAGCTTTCCCCGATGGCTGGGGTGA
  GGTGCCTTTAAAACTTTTGGGGAGCCCTGCCTTCCCTACTAAGTTTTCCCGATTTTTTTG
  CCACCTTTTTGGGGGGGCCAGCCTCCCCCCAGGGTACTCAAAGGCCCCTCAAAGGGCAGG
  GTTGGGGGGGGCAAACAACGGGACCTGGTCACAACGGGTAGGGGGGGGCTCCCCCAACAG
  GGAAGGGCGGGAACACAACTCCCCGTCCCGGAGCACCTCGGGCAGGAGCTTGCGCTTGGT
  CTCCGGCACCACCATAATGCTGAAAATGCAAAGGAGGGGGCAGGCCCCCCACACCCCGTG
  CTGGAGGAAGGCTCCATGGCCCATGGGGAGGCCCTGGGCCGGGCCCCTTAATCCTCCAAG
  CGCCCCTAGAGCCATGATCAGGCCCAGGCCCGGGCCCCGGGAAGTGGGGGGGGATGACCC
  CACCACCAAGGAGGGTGCCCGGGTAGGCGGCACTTTGGGAGGAAAAAACCCCCGGACACA
  AAAAGTGGGGAGGGC
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_020372
• ORF Size: 1617 bp
• Insert Size: 2250
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_020372.2, NP_065105.2
• RefSeq Size: 2090
• RefSeq ORF: 1617
• Locus ID: 51310
• Domains: sugar_tr
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) encodes the longest isoform (a).