TIGAR (NM_020375) Human Untagged Clone

CAT#: SC113108

C12orf5 (untagged)-Human chromosome 12 open reading frame 5 (C12orf5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TIGAR
• Synonyms: C12orf5; FR2BP
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC113108 sequence for NM_020375 edited (data generated by NextGen Sequencing)
  ATGGCTCGCTTCGCTCTGACTGTTGTCCGGCATGGAGAAACAAGATTTAACAAGGAGAAA
  ATAATCCAAGGACAAGGAGTAGATGAACCTCTTTCAGAAACTGGATTTAAACAAGCAGCA
  GCTGCTGGTATATTTCTGAATAATGTGAAGTTTACTCATGCTTTCTCCAGTGATCTCATG
  AGGACAAAGCAGACCATGCATGGAATTTTGGAGAGAAGCAAATTTTGCAAAGATATGACG
  GTAAAGTATGACTCAAGACTTCGGGAAAGGAAATACGGGGTTGTAGAAGGCAAAGCGCTA
  AGTGAGCTGAGGGCCATGGCCAAAGCAGCCAGGGAAGAGTGCCCTGTGTTTACACCGCCC
  GGAGGAGAGACGCTGGACCAGGTGAAAATGCGTGGAATAGACTTTTTTGAATTTCTTTGT
  CAACTAATCCTGAAAGAAGCGGATCAAAAAGAACAGTTTTCCCAAGGATCTCCAAGCAAC
  TGTCTGGAAACTTCTTTGGCAGAGATATTTCCTTTAGGAAAAAATCACAGCTCTAAAGTT
  AATTCAGACAGCGGTATTCCAGGATTAGCAGCCAGTGTCTTAGTTGTGAGTCACGGTGCT
  TACATGAGAAGTCTGTTTGATTATTTTCTGACTGACCTTAAGTGTTCCTTACCAGCCACT
  CTGAGCAGATCTGAACTTATGTCAGTCACTCCCAATACAGGGATGAGTCTCTTTATCATA
  AACTTTGAGGAAGGAAGAGAAGTTAAACCAACGGTTCAGTGTATTTGTATGAACCTACAG
  GATCATCTAAATGGACTGACTGAAACTCGCTAA
  
  Clone variation with respect to NM_020375.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020375 unedited
  NTGTTCAGATTTTGNTATACGAACTCACTATAGGGCGGCCGCGATTCGGCACGAGGGGCC
  CGCAGTGCAGGGGCAGCGCGGCGCGGGGCCACCGACGGGACGCGGCTCCGGGAACATGGC
  TCGCTTCGCTCTGACTGTTGTCCGGCATGGAGAAACAAGATTTAACAAGGAGAAAATAAT
  CCAAGGACAAGGAGTAGATGAACCTCTTTCAGAAACTGGATTTAAACAAGCAGCAGCTGC
  TGGTATATTTCTGAATAATGTGAAGTTTACTCATGCTTTCTCCAGTGATCTCATGAGGAC
  AAAGCAGACCATGCATGGAATTTTGGAGAGAAGCAAATTTTGCAAAGATATGACGGTAAA
  GTATGACTCAAGACTTCGGGAAAGGAAATACGGGGTTGTAGAAGGCAAAGCGCTAAGTGA
  GCTGAGGGCCATGGCCAAAGCAGCCAGGGAAGAGTGCCCTGTGTTTACACCGCCCGGAGG
  AGAGACGCTGGACCAGGTGAAAATGCGTGGAATAGACTTTTTTGAATTTCTTTGTCAACT
  AATCCTGAAAGAAGCGGATCAAAAAGAACAGCTTTCCCAAGGATCTCCAAGCAACTGTCT
  GGAAACTTCTTTGGCAGAGATATTTCCTTTACGAAAAAATCACAGCTCTAAAGTTAATTC
  AGACAGCGGTATTCCAGGATTAGCAGCCAGTGTCTTAGTTGTGAGTCACGGTGCTCACAT
  GAGAAGCCTGTTTGATTATTTTCTGACTGACCTTAAGTGTTCCCTACCAGCCACTCTGAG
  CAGATCTGAACTTATGTCAGTCACCTCCCATACAGGGATGAGTCCTTTTATTATAACCTT
  GAAGAAGGAAGAGAATTAAACCACCGGCCCATGGAATTGAATGAACCAACGGATCTCTAA
  TGGACTGACG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020375 unedited
  CGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTAAACTTATAAGGATT
  TTTTATTTAAAGGATTTAAAAATATAACACAGTCAATATAAACATGTACTGGGAATTATA
  AACCATTCTTTCTTCTAAGCACTGGATGAGATACTAAAAACATACAGTATCTTACCAATA
  GCCATTAAAATAGGCTAAAATGAAAAAGAAACCGTTGTAACAAGGTTACTAATCCCCCAA
  CTTTCAATGCTGAGTTCCTTCATCATCCATGTGCAATCCAGAGATGACATCTAGCAGGGT
  GGTAAAATTATTCTGGAAAATGCCAACTGTACTTGGACAAAATAAGTTAATTCTATATGG
  TTGTCCATTAAAGTTTTATGTGGCTATGGTTCCACTGGAGCTAAAAATTGGCTTTTAACT
  GTTTCCAAATCAGAACTAGCAGAGGAGAGAAGTAAATAAAGCCAATGGCACTCCCTTCAG
  AGGCTCAAAATGGTTAGATTTTGATGCAGATTTAACCTTAGCGAGTTTCAGTCAGTCCAT
  TTAGATGATCCTGTAGGTTCATACAAATACACTGAACCGTTGGTTTAACTTCTCTTCCTT
  CCTCAAAGTTTATGATAAAGAGACTCATCCCTGTATTGGGAGTGACTGACATAAGTTCAG
  ATCTGCTCAGAGTGGCTGGTAAGGAACACTTAAGGTCAGTCAGAAAATAATCAAACAGAC
  TTCTCATGTAAGCACCGTGACTCACAACTAAGACACTGGCTGCTAATCCTGGAATACCGC
  TGTCTGAATTAACTTAGAGCTGTGATTTTTTCCTAAAGGAATATCTCTGCCAAAGAAGTT
  TCAGACAGTTGCTTGGAGATCCTTGGGAAAACTGTCTTTTTGATCCGCTTCTTCAGGGAT
  AGTTGACAAAGAATCAAAAAGNCTATTCCAGCTTTTCACTGGCCAGCGTTTTCCTCGGGC
  GTGTAAACCAGGCACTCTTCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_020375
• ORF Size: 813 bp
• Insert Size: 1410
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_020375.1, NP_065108.1
• RefSeq Size: 1361
• RefSeq ORF: 813
• Locus ID: 57103
• Domains: PGAM
• Gene Summary: This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq, Jul 2008]