TIGAR (NM_020375) Human Untagged Clone

CAT#: SC320794

C12orf5 (untagged)-Human chromosome 12 open reading frame 5 (C12orf5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TIGAR
• Synonyms: C12orf5; FR2BP
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_020375.2 GCGGCGCGGGGCCACCGACGGGACGCGGCTCCGGGAACATGGCTCGCTTCGCTCTGACTG
  TTGTCCGGCATGGAGAAACAAGATTTAACAAGGAGAAAATAATCCAAGGACAAGGAGTAG
  ATGAACCTCTTTCAGAAACTGGATTTAAACAAGCAGCAGCTGCTGGTATATTTCTGAATA
  ATGTGAAGTTTACTCATGCTTTCTCCAGTGATCTCATGAGGACAAAGCAGACCATGCATG
  GAATTTTGGAGAGAAGCAAATTTTGCAAAGATATGACGGTAAAGTATGACTCAAGACTTC
  GGGAAAGGAAATACGGGGTTGTAGAAGGCAAAGCGCTAAGTGAGCTGAGGGCCATGGCCA
  AAGCAGCCAGGGAAGAGTGCCCTGTGTTTACACCGCCCGGAGGAGAGACGCTGGACCAGG
  TGAAAATGCGTGGAATAGACTTTTTTGAATTTCTTTGTCAACTAATCCTGAAAGAAGCGG
  ATCAAAAAGAACAGTTTTCCCAAGGATCTCCAAGCAACTGTCTGGAAACTTCTTTGGCAG
  AGATATTTCCTTTAGGAAAAAATCACAGCTCTAAAGTTAATTCAGACAGCGGTATTCCAG
  GATTAGCAGCCAGTGTCTTAGTTGTGAGTCACGGTGCTTACATGAGAAGTCTGTTTGATT
  ATTTTCTGACTGACCTTAAGTGTTCCTTACCAGCCACTCTGAGCAGATCTGAACTTATGT
  CAGTCACTCCCAATACAGGGATGAGTCTCTTTATCATAAACTTTGAGGAAGGAAGAGAAG
  TTAAACCAACGGTTCAGTGTATTTGTATGAACCTACAGGATCATCTAAATGGACTGACTG
  AAACTCGCTAAGGTTAAATCTGCATCAAAATCTAACCATTTTGAGCCTCTGAAGGGAGTG
  CCATTGGCTTTATTTACTTCTCTCCTCTGCTAGTTCTGATTTGGAAACAGTTAAAAGCCA
  ATTTTTAGCTCCAGTGGAACCATAGCCACATAAAACTTTAATGGACAACCATATAGAATT
  AACTTATTTTGTCTAAGTACAGTTGGCATTTTCCAGAATAATTTTACCACCCTGCTAGAT
  GTCATCTCTGGATTGCACATGGATGATGAAGGAACTCAGCATTGAAAGTTGGGGGATTAA
  TAACCTTGTTACAACGGTTTCTTTTTCATTTTAGCCTATTTTAATGGCTATTGGTAAGAT
  ACTGTATGTTTTTAGTATCTCATCCAGTGCTTAGAAGAAAGAATGGTTTATAATTCCCAG
  TACATGTTTATATTGACTGTGTTATATTTTTAAATCCTTTAAATAAAAAATCCTTATAAG
  TTTATGTAAAGCAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020375.2 unedited
  TCACTGTATACGACTCCTATAGGGCGGCCGGGAATTCGGCACGAGGGCGGCGCGGGGCCA
  CCGACGGGACGCGGCTCCGGGAACATGGCTCGCTTCGCTCTGACTGTTGTCCGGCATGGA
  GAAACAAGATTTAACAAGGAGAAAATAATCCAAGGACAAGGAGTAGATGAACCTCTTTCA
  GAAACTGGATTTAAACAAGCAGCAGCTGCTGGTATATTTCTGAATAATGTGAAGTTTACT
  CATGCTTTCTCCAGTGATCTCATGAGGACAAAGCAGACCATGCATGGAATTTTGGAGAGA
  AGCAAATTTTGCAAAGATATGACGGTAAAGTATGACTCAAGACTTCGGGAAAGGAAATAC
  GGGGTTGTAGAAGGCAAAGCGCTAAGTGAGCTGAGGGCCATGGCCAAAGCAGCCAGGGAA
  GAGTGCCCTGTGTTTACACCGCCCGGAGGAGAGACGCTGGACCAGGTGAAAATGCGTGGA
  ATAGACTTTTTTGAATTTCTTTGTCAACTAATCCTGAAAGAAGCGGATCAAAAAGAACAG
  TTTTCCCAAGGATCTCCAAGCAACTGTCTGGAAACTTCTTTTGGCAGAGATATTTCCTTT
  AGGAAAAAATCACAGCTCTAAAGTTAATTCAGACAGCGGTATTCCAGGATTAGCAGCCAG
  TGTCTTAGTTGTGAGTCACGGTGCTTACATGAGAAGTCTGTTTGATTATTTTCTGACTGA
  CCTTAAGTGTTCCTTACCAGCCACTCTGAGCAGATCTGAACTTATTGTCAGTCACTCCCA
  ATACAGGGATGAGTCTCTTTATCATAAACTTTGAGAGAGAGAGTTAACCAACGGTTCAGT
  GTATTTTGTATGAACCTACAGATCATCTAATGGACTGACTGAAACTCGCTGAGTAATCTG
  CATCAAATCTAACCATTTGGAGCCTTCTGAAGGGGAGTGCCATTGGATATGAC
• Restriction Sites: Please inquire
• ACCN: NM_020375
• ORF Size: 813 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_020375.2, NP_065108.1
• RefSeq Size: 8237
• RefSeq ORF: 813
• Locus ID: 57103
• Domains: PGAM
• Gene Summary: This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq, Jul 2008]