GTPBP4 (NM_012341) Human Untagged Clone

CAT#: SC115395

GTPBP4 (untagged)-Human GTP binding protein 4 (GTPBP4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GTPBP4
• Synonyms: CRFG; NGB; NOG1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115395 sequence for NM_012341 edited (data generated by NextGen Sequencing)
  ATGGCACATTACAACTTCAAGAAAATTACGGTGGTGCCGTCCGCCAAGGACTTCATAGAC
  CTCACGTTGTCGAAGACTCAACGAAAGACTCCAACCGTTATTCATAAACATTACCAAATA
  CATCGCATTAGACATTTTTACATGAGAAAAGTCAAATTTACTCAACAGAATTACCATGAT
  AGACTTTCACAAATTCTAACAGATTTCCCCAAATTGGATGATATTCATCCGTTCTATGCT
  GATTTGATGAATATTCTCTACGACAAGGATCATTACAAGTTGGCTCTGGGGCAAATAAAT
  ATTGCCAAAAATTTAGTGGACAATGTTGCTAAAGATTATGTGCGACTGATGAAGTATGGC
  GACTCTCTCTACCGCTGCAAACAGCTGAAGCGTGCGGCCCTGGGACGGATGTGCACAGTG
  ATCAAGAGGCAGAAGCAGAGTTTGGAGTATTTGGAGCAAGTGCGTCAGCATTTATCCCGT
  TTGCCAACCATTGATCCGAATACCAGGACCCTGCTTTTGTGTGGGTACCCAAATGTTGGG
  AAGTCCAGCTTCATCAACAAGGTGACGAGAGCAGACGTGGATGTCCAGCCCTATGCGTTC
  ACAACCAAGTCTCTGTTTGTTGGGCACATGGATTATAAGTATCTACGTTGGCAGGTTGTA
  GACACTCCTGGGATCCTGGACCACCCTCTGGAGGATAGGAACACCATCGAGATGCAGGCC
  ATCACTGCCCTGGCCCACCTCCGTGCTGCGGTCCTGTATGTGATGGATTTGTCTGAGCAG
  TGTGGGCATGGGCTGAGGGAGCAGCTAGAACTCTTCCAGAACATCAGACCTCTCTTCATC
  AACAAGCCTCTCATAGTTGTAGCCAACAAATGTGATGTGAAGAGAATAGCTGAACTTTCT
  GAAGATGATCAGAAAATATTTACAGATTTGCAGTCTGAAGGATTCCCTGTAATAGAGACC
  AGCACCCTGACTGAGGAAGGTGTTATTAAAGTTAAAACAGAGGCTTGCGATAGGCTTTTG
  GCTCATCGAGTGGAAACCAAAATGAAGGGAAATAAAGTGAATGAGGTGCTGAATAGACTG
  CACCTGGCTATCCCAACCAGGAGGGACAATAAGGAGAGGCCCCCTTTCATCCCTGAAGGA
  GTGGTGGCTCGCAGGAAGAGGATGGAAACTGAGGAGTCCAGGAAGAAGAGGGAACGAGAT
  CTTGAGCTGGAAATGGGAGATGATTATATTTTGGATCTTCAGAAGTACTGGGATTTAATG
  AATTTGTCTGAAAAACATGATAAGATACCAGAAATCTGGGAAGGCCATAATATAGCTGAT
  TATATTGATCCAGCCATCATGAAGAAATTGGAAGAATTAGAAAAAGAAGAAGAGCTGAGA
  ACAGCTGCTGGAGAGTATGACAGTGTATCTGAGAGTGAAGACGAAGAGATGCTGGAAATC
  CGACAGCTGGCAAAGCAAATTCGAGAGAAAAAGAAGTTGAAAATTCTGGAGTCCAAAGAA
  AAGAATACACAGGGACCCAGGATGCCGCGAACTGCTAAGAAGGTTCAGAGGACAGTTTTG
  GAGAAGGAGATGCGTAGTCTTGGTGTTGACATGGACGATAAAGACGATGCCCATTACGCA
  GTCCAGGCAAGAAGATCCCGGAGCATCACTAGGAAAAGAAAGCGGGAAGACTCTGCTCCC
  CCGTCCTCTGTGGCCCGGAGTGGGAGTTGCTCTCGAACTCCACGTGACGTTTCTGGTCTT
  AGGGATGTCAAGATGGTGAAGAAAGCCAAGACTATGATGAAGAATGCTCAGAAGAAGATG
  AATCGGTTGGGGAAGAAAGGGGAGGCGGATAGACACGTGTTTGATATGAAGCCCAAGCAC
  TTGCTGTCTGGGAAGAGGAAAGCTGGTAAAAAGGACAGGAGATAG
  
  Clone variation with respect to NM_012341.2
  1108 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012341 unedited
  GGTTCAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGCCAAGTAC
  CCGCGTGCATACGGCTGCCGGCATGGCACATTACAACTTCAAGAAAATTACGGTGGTGCC
  GTCCGCCAAGGACTTCATAGACCTCACGTTGTCGAAGACTCAACGAAAGACTCCAACCGT
  TATTCATAAACATTACCAAATACATCGCATTAGACATTTTTACATGAGAAAAGTCAAATT
  TACTCAACAGAATTACCATGATAGACTTTCACAAATTCTAACAGATTTCCCCAAATTGGA
  TGATATTCATCCGTTCTATGCTGATTTGATGAATATTCTCTACGACAAGGATCATTACAA
  GTTGGCTCTGGGGCAAATAAATATTGCCAAAAATTTAGTGGACAATGTTGCTAAAGATTA
  TGTGCGACTGATGAAGTATGGCGACTCTCTCTACCGCTGCAAACAGCTGAAGCGTGCGGC
  CCTGGGACGGATGTGCACAGTGATCAAGAGGCAGAAGCAGAGTTTGGAGTATTTGGAGCA
  AGTGCGTCAGCATTTATCCCGTTTGCCAACCATTGATCCGAATACCAGGACCCTGCTTTT
  GTGTGGGTACCCAAATGTTGGGAAGTCCAGCTTCATCAACAAGGTGACGAGAGCAGACGT
  GGATGTCCAGCCCTATGCGTTCACAACCAAGTCTCTGTTTGTTGGGCACATGGATTATAA
  GTATCTACGTTGGCAGGTTGTAGACACTCCTGGGATCCTGGACCACCCTCTGGAGGATAG
  GAACACCATCGAGATGCAGGCCATCACTGCCCTGGCCCANCTNCGTGCTGCGGTCCTGTA
  TGTGATGGATTTGTCTGANCAGTGTGGGCATGGGCTGAGGNAGCAGCTANAACTCTTCCA
  GAACATCAGACCTCTCTCAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012341 unedited
  CCATCTTGNCCGCGGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTTTAAATGAAAA
  CTACTTTCTTCTGGGGGTTTATTTTGGATAAAATAGTTGAAGACAGACTACAATGAGACA
  TTGTAAAATAAGACTAGAAAATAATTTAAGAGCGTATTTTAAGCACGGGATTCCGACACA
  CTCATAAACGTGTTTGCTCCCAGCTCTTACAAAAGAAAATAAGGTTTTTCTCCATCAAAA
  ACAACCCAGTTACACCAGTAAATCTTCCCAGTTCTGAAAATCTGAAGCAACTGATACTCC
  ATTAAATGTGGAAACACTGTCTACTCAAAATATTTGTAATATTATGCAGTGACAAAAATT
  TCCCACACCTATATAGGGTTAACCATAGTTTTCAGCAAAGCAACAAGTGCTTTACTTATT
  TTGTCTTTTTCAGTTTATACAGAGCTCCAATTTCATGAAACCATACTGTGCCAAACCAGG
  AAATAAACAGCAACACTCTAGCGAAGCCACGCCAACCAAACGGATACTATCTCCTGTCCT
  TTTTACCAGCTTTCCTCTTCCCAACAGCAAGTGCTTGGGCTTCATATCAAACACGTGTCT
  ATCCGCCTNCCCTTTCTTCCCCAACCGATTCATCTTCTTCTGAGCATTCTTCATCATAGT
  CTTGGCTTTTCTCACCCATCTGACATCCCCTAAGACANAAACGTCACGTTGGAGTTCGAG
  AGCAACTCCCACTTCGGGCCACANAAGACAGGGGAGCAGAATCTTCCCGCTTTTTTTTTC
  TAAGGATGCTCGGGATCTTCTGCCTGGACTGCGTAAGGGCATTCCTTTATAGGCCTGGTA
  AAACCAGAATACCATTTCCTTTTCAAAAATGTCTTTGAACTTTTAACGTTCCCGGGATCG
  GGGCCCTGGGATTTTTTCTTTGGACACCAATTCAACCTTTTTTTTTTT
  
• Restriction Sites: ECoRI-NOT
• ACCN: NM_012341
• ORF Size: 1905 bp
• Insert Size: 2500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012341.2, NP_036473.2
• RefSeq Size: 2537
• RefSeq ORF: 1905
• Locus ID: 23560
• Protein Families: Druggable Genome
• Gene Summary: GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008]