GTPBP4 (NM_012341) Human Untagged Clone

CAT#: SC323991

GTPBP4 (untagged)-Human GTP binding protein 4 (GTPBP4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GTPBP4
• Synonyms: CRFG; NGB; NOG1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_012341.2 GGACGCGTGGGCGCGTGCATACGGCTGCCGGCATGGCACATTACAACTTCAAGAAAATTA
  CGGTGGTGCCGTCCGCCAAGGACTTCATAGACCTCACGTTGTCGAAGACTCAACGAAAGA
  CTCCAACCGTTATTCATAAACATTACCAAATACATCGCATTAGACATTTTTACATGAGAA
  AAGTCAAATTTACTCAACAGAATTACCATGATAGACTTTCACAAATTCTAACAGATTTCC
  CCAAATTGGATGATATTCATCCGTTCTATGCTGATTTGATGAATATTCTCTACGACAAGG
  ATCATTACAAGTTGGCTCTGGGGCAAATAAATATTGCCAAAAATTTAGTGGACAATGTTG
  CTAAAGATTATGTGCGACTGATGAAGTATGGCGACTCTCTCTACCGCTGCAAACAGCTGA
  AGCGTGCGGCCCTGGGACGGATGTGCACAGTGATCAAGAGGCAGAAGCAGAGTTTGGAGT
  ATTTGGAGCAAGTGCGTCAGCATTTATCCCGTTTGCCAACCATTGATCCGAATACCAGGA
  CCCTGCTTTTGTGTGGGTACCCAAATGTTGGGAAGTCCAGCTTCATCAACAAGGTGACGA
  GAGCAGACGTGGATGTCCAGCCCTATGCGTTCACAACCAAGTCTCTGTTTGTTGGGCACA
  TGGATTATAAGTATCTACGTTGGCAGGTTGTAGACACTCCTGGGATCCTGGACCACCCTC
  TGGAGGATAGGAACACCATCGAGATGCAGGCCATCACTGCCCTGGCCCACCTCCGTGCTG
  CAGTCCTGTATGTGATGGATTTGTCTGAGCAGTGTGGGCATGGGCTGAGGGAGCAGCTAG
  AACTCTTCCAGAACATCAGACCTCTCTTCATCAACAAGCCTCTCATAGTTGTAGCCAACA
  AATGTGATGTGAAGAGAATAGCTGAACTTTCTGAAGATGATCAGAAAATATTTACAGATT
  TGCAGTCTGAAGGATTCCCTGTAATAGAGACCAGCACCCTGACTGAGGAAGGTGTTATTA
  AAGTTAAAACAGAGGCTTGCGATAGGCTTTTGGCTCATCGAGTGGAAACCAAAATGAAGG
  GAAATAAAGTGAATGAGGTGCTGAATAGACTGCACCTGGCTATCCCAACCAGGAGGGACG
  ATAAGGAGAGGCCCCCTTTCATCCCTGAAGGAGTGGTGGCTCGCAGGAAGAGGATGGAAA
  CTGAGGAGTCCAGGAAGAAGAGGGAACGAGATCTTGAGCTGGAAATGGGAGATGATTATA
  TTTTGGATCTTCAGAAGTACTGGGATTTAATGAATTTGTCTGAAAAACATGATAAGATAC
  CAGAAATCTGGGAAGGCCATAATATAGCTGATTATATTGATCCAGCCATCATGAAGAAAT
  TGGAAGAATTAGAAAAAGAAGAAGAGCTGAGAACAGCTGCTGGAGAGTATGACAGTGTAT
  CTGAGAGTGAAGACGAAGAGATGCTGGAAATCCGACAGCTGGCAAAGCAAATTCGAGAGA
  AAAAGAAGTTGAAAATTCTGGAGTCCAAAGAAAAGAATACACAGGGACCCAGGATGCCGC
  GAACTGCTAAGAAGGTTCAGAGGACAGTTTTGGAGAAGGAGATGCGTAGTCTTGGTGTTG
  ACATGGACGATAAAGACGATGCCCATTACGCAGTCCAGGCAAGAAGATCCCGGAGCATCA
  CTAGGAAAAGAAAGCGGGAAGACTCTGCTCCCCCGTCCTCTGTGGCCCGGAGTGGGAGTT
  GCTCTCGAACTCCACGTGACGTTTCTGGTCTTAGGGATGTCAAGATGGTGAAGAAAGCCA
  AGACTATGATGAAGAATGCTCAGAAGAAGATGAATCGGTTGGGGAAGAAAGGGGAGGCGG
  ATAGACACGTGTTTGATATGAAGCCCAAGCACTTGCTGTCTGGGAAGAGGAAAGCTGGTA
  AAAAGGACAGGAGATAGTATCCGTTTGGTTGGCGTGGCTTCGCTAGAGTGTTGCTGTTTA
  TTTCCTGGTTTGGCACAGTATGGTTTCATGAAATTGGAGCTCTGTATAAACTGAAAAAGA
  CAAAATAAGTAAAGCACTTGTTGCTTTGCTGAAAACTATGGTTAACCCTATATAGGTGTG
  GGAAATTTTTGTCACTGCATAATATTACAAATATTTTGAGTAGACAGTGTTTCCACATTT
  AATGGAGTATCAGTTGCTTCAGATTTTCAGAACTGGGAAGATTTACTGGTGTAACTGGGT
  TGTTTTTGATGGAGAAAAACCTTATTTTCTTTTGTAAGAGCTGGGAGCAAACACGTTTAT
  GAGTGTGTCGGAATCCCGTGCTTAAAATACGCTCTTAAATTATTTTCTAGTCTTATTTTA
  CAATGTCTCATTGTAGTCTGTCTTCAACTATTTTATCCAAAATAAACCTCCAGAAGAAAG
  TAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012341.2 unedited
  TACACTTTGTATACGACTCCTATAGGGCGGCCGGCGTATCGCGGCGCGCCGGTACCGGTC
  CGGAATTCCCGGGATATCGTCGACCCACGCGTCCGCGGACGCGTGGGCGCGTGCATACGG
  CTGCCGGCATGGCACATTACAACTTCAAGAAAATTACGGTGGTGCCGTCCGCCAAGGACT
  TCATAGACCTCACGTTGTCGAAGACTCAACGAAAGACTCCAACCGTTATTCATAAACATT
  ACCAAATACATCGCATTAGACATTTTTACATGAGAAAAGTCAAATTTACTCAACAGAATT
  ACCATGATAGACTTTCACAAATTCTAACAGATTTCCCCAAATTGGATGATATTCATCCGT
  TCTATGCTGATTTGATGAATATTCTCTACGACAAGGATCATTACAAGTTGGCTCTGGGGC
  AAATAAATATTGCCAAAAATTTAGTGGACAATGTTGCTAAAGATTATGTGCGACTGATGA
  AGTATGGCGACTCTCTCTACCGCTGCAAACAGCTGAAGCGTGCGGCCCTGGGACGGATGT
  GCACAGTGATCAAGAGGCAGAAGCAGAGTTTGGAGTATTTGGAGCAAGTGCGTCAGCATT
  TATCCCGTTTGCCAACCATTGATCCGAATACCAGGACCCTGCTTTTGTGTGGGTACCCAA
  TGTTGGGAAGTCCAGCTTCATCAACAGGGTGACGAGAGCAGACGTGGATGTCCAGCCCTA
  TGCGTTCACAACACAATCTCTGTATGTTGGGCACATGGATATAAGTATCTACGTTGGCCA
  GGTTGCGAACCTCTGAGATCCTGAACCCGCCTCCGGACGAGTGGATCACATCAAATAGAG
  GGCAGCACTGGCTCTACCAACTAGAGC
• Restriction Sites: ECoRI-NOT
• ACCN: NM_012341
• ORF Size: 1905 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_012341.2, NP_036473.2
• RefSeq Size: 2537
• RefSeq ORF: 1905
• Locus ID: 23560
• Protein Families: Druggable Genome
• Gene Summary: GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008]