TKTL1 (NM_012253) Human Untagged Clone

CAT#: SC115462

TKTL1 (untagged)-Human transketolase-like 1 (TKTL1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TKTL1
• Synonyms: TKR; TKT2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_012253, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGATGCTGAGGCGAGGGCTGAGTTCCCGGAGGAGGCCAGACCTGACAGGGGCACCTTGCAGGTGT
  TGCAAGATATGGCCAGCCGCTTGCGAATCCATTCCATCAGGGCCACATGCTCCACGAGCTCCGGCCACCC
  TACATCATGTAGCAGTTCTTCTGAGATCATGTCTGTGCTGTTCTTCTACATCATGAGGTACAAGCAGTCA
  GATCCAGAGAATCCGGACAACGACCGATTTGTCCTCGCAAAGAGACTGTCGTTTGTGGATGTGGCAACAG
  GATGGCTCGGACAAGGACTGGGAGTTGCATGTGGAATGGCATATACTGGCAAGTACTTCGACAGGGCCAG
  CTACCGGGTGTTCTGCCTCATGAGTGATGGCGAGTCCTCAGAAGGCTCTGTCTGGGAGGCAATGGCCTTT
  GCTTCCTACTACAGTCTGGACAATCTTGTGGCAATCTTTGATGTGAACCGCCTGGGACACAGTGGTGCAT
  TGCCCGCCGAGCACTGCATAAACATCTATCAGAGGCGCTGCGAAGCCTTTGGGTGGAACACTTATGTGGT
  GGACGGCCGGGACGTGGAGGCACTGTGCCAGGTATTCTGGCAGGCTTCTCAGGTGAAGCACAAGCCCACT
  GCTGTGGTGGCCAAGACCTTCAAGGGCCGGGGCACCCCAAGTATTGAGGATGCAGAAAGTTGGCATGCAA
  AGCCAATGCCGAGAGAAAGAGCAGATGCCATTATCAAATTAATTGAGAGCCAGATACAGACCAGCAGGAA
  TCTTGACCCACAGCCCCCCATTGAGGACTCACCTGAAGTCAACATCACAGATGTAAGGATGACCTCTCCA
  CCTGATTACAGAGTTGGTGACAAGATAGCTACTCGGAAAGCATGCGGTCTGGCTCTGGCTAAGCTGGGCT
  ACGCGAACAACAGAGTCGTTGTGCTGGATGGTGACACCAGGTACTCTACTTTCTCTGAGATATTCAACAA
  GGAGTACCCTGAGCGCTTCATCGAGTGCTTTATGGCTGAACAAAACATGGTGAGCGTGGCTCTGGGCTGT
  GCCTCCCGTGGACGGACCATTGCTTTTGCTAGCACCTTTGCTGCCTTTCTGACTCGAGCATTTGATCACA
  TCCGGATAGGAGGCCTCGCTGAGAGCAACATCAACATTATTGGTTCCCACTGTGGGGTATCTGTTGGTGA
  CGATGGTGCTTCCCAGATGGCCCTGGAGGATATAGCCATGTTCCGAACCATTCCCAAGTGCACGATCTTC
  TACCCAACTGATGCCGTCTCCACGGAGCATGCTGTTGCTCTGGCAGCCAATGCCAAGGGGATGTGCTTCA
  TTCGGACCACCCGACCAGAAACTATGGTTATTTACACCCCACAAGAACGCTTTGAGATCGGACAGGCCAA
  GGTCCTCCGCCACTGTGTCAGTGACAAGGTCACAGTTATTGGAGCTGGAATTACTGTGTATGAAGCCTTA
  GCAGCTGCTGATGAGCTTTCGAAACAAGATATTTTTATCCGTGTCATCGACCTGTTTACCATTAAACCTC
  TGGATGTCGCCACCATCGTCTCCAGTGCAAAAGCCACAGAGGGCCGGATCATTACAGTGGAGGATCACTA
  CCCGCAAGGTGGCATCGGGGAAGCTGTCTGCGCAGCCGTCTCCATGGATCCTGACATTCAGGTTCATTCG
  CTGGCAGTGTCGGGAGTGCCCCAGAGTGGGAAGTCCGAGGAATTGCTGGATATGTATGGAATTAGTGCCA
  GACATATCATAGTGGCCGTGAAATGCATGTTGCTGAACTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012253 unedited
  CGTTAGGATTTGAATACGACTTACTATAGGCGGCCGCGCAATTCGCACGAGGTTGGATTC
  CTTCCGGGCTGGGAGAAAGACCGCTTCTATGAGGAGACCATGTGCCGAGGTCGTGTGCTA
  GGAAGCCAGTTGCTGTGAGAAATGACCAGTGTCATGTCTGTCTTTCAGCCACCCTACATC
  ATGTAGCAGTTCTTCTGAGATCATGTCTGTGCTGTTCTTCTACATCATGAGGTACAAGCA
  GTCAGATCCAGAGAATCCGGACAACGACCGATTTGTCCTCGCAAAGAGACTGTCGTTTGT
  GGATGTGGCAACAGGATGGCTCGGACAAGGACTGGGAGTTGCATGTGGAATGGCATATAC
  TGGCAAGTACTTCGACAGGGCCAGCTACCGGGTGTTCTGCCTCATGAGTGATGGCGAGTC
  CTCAGAAGGCTCTGTCTGGGAGGCAATGGCCTTTGCTTCCTACTACAGTCTGGACAATCT
  TGTGGCAATCTTTGATGTGAACCGCCTGNGACACAGTGGTGCATTGCCCGCCGAGCACTG
  CATAAACATCTATCAGAGGCGCTGCGAAGCCTTTGGGTGGAACACTTATGTGGTGGACGG
  CCGGGACGTGGAGGCACTGTGCCAGGTATTCTGGCAGGCTTCTCAGGTGAAGCACAAGCC
  CACTGCTGTGGTGGCCAAGACCTCTCAGGGGCCGGGGCACCCCAAGTATTGAGGATGCAN
  AAAGTTGGCATGCAAAGCCAATGCCGAGAGAAAGAGCAGATGCCATTATCAAATTTAATT
  GAGAGCCAGATACAGACCAGCAGGAAATCTTGACCCACAGCCCCCCCATTNGAGGACTCA
  CCCTGAAGTCACATCACAGATGTGAGGGATGACCTCTCCACCTGATTACCAGAGTTGGTG
  ACAAGAAAGCCTCCTCGGAAGCATGCCGGCCTGGCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012253 unedited
  GCGGGGGGGCACCCCCNCCCCCTCTTNNCCCCNNNTTTGCTTGNNACCGCGGCCGCATTC
  TAGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTGAATAAAGCAGCTGGTTTTGAAATGC
  TTTATTAACATTGACTTGAACAGTACAGTGTGGAGGCTCTCATCACAAGCAGCACAGGAC
  ATCCTAACAAGCTTTCGCTGCTGCCTGACAGCCTCTCAAACGTGGAGGGAGATGAAGGCA
  AACAGCGAAGGGAATTCCAGGGCAGCTGCAGGTGGGATGGCAGCACACAGAATCCCAAGG
  TGGGAACAGCAGTAGGCGTCATGGTGTTATCGTGCTGTGGAAACTAGGCTACTGGAATCT
  ATACTTCAATCCACATTTTCTTTACTCATGAAGGAAATACATTGAAAAAACTATTACCTC
  TACCAGTTATTCACGAAGGAAACACTTCGGAAGAATTGATTACCTCTACCACTTATCTAT
  AGTCTTATCAGAAAACTTACTATCAGGTGGTTGTTTTGTTACCTATTTTTTTCACTTAAA
  AGTTGTGTAACTCCCTTTAATGATCCAAAAATTAGAGCGGTACTTGCATATGCAGTGACA
  GTTTAAAGGGGTAGTAAGTAGCTTTGATTTCCGAACTAGGGATGAATGAAGGTGTTAGCT
  GGCTTTGCTTTTAAGAAACAAAATGTGACAGTAGAGATTTAAATGATGGGTTTGGGACAA
  ACATAAACACAGGGTGAAAGATGCCAAAAAGACCAAAGCTAACAGCTTTTTTAATTAACC
  ACCTGGCATTTCACGGCCCCTATGAAATGGCTGGCACCTAATCCATACCTATCCAGCAAT
  TCCCTGGACCTTCCCCTTTGGGGGCACTCCGACACTTGCACCGAATGAACCTGAATGTCA
  GGAATCCATGTAAAACGTTTGGCCCAACAATTTCCCCGAGCCCCCTTGGGCGGAAGGGAA
  CCCCCCCCGGAAGGAATCCGCCCCTTGGGGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012253
• ORF Size: 2652 bp
• Insert Size: 2620
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_012253.1, NP_036385.1
• RefSeq Size: 2652
• RefSeq ORF: 2652
• Locus ID: 8277
• Domains: transketolase, transket_pyr, transketolase_C
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Pentose phosphate pathway
• Gene Summary: The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).