IRAKM (IRAK3) (NM_007199) Human Untagged Clone

CAT#: SC115680

IRAK3 (untagged)-Human interleukin-1 receptor-associated kinase 3 (IRAK3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IRAK3
• Synonyms: ASRT5; IRAKM
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_007199 edited
  ATGGCGGGGAACTGTGGGGCCCGCGGCGCGCTGTCGGCGCACACGCTGCTGTTCGACCTG
  CCGCCCGCGCTGCTCGGAGAGCTCTGCGCTGTTCTGGACAGCTGCGACGGCGCGCTGGGC
  TGGCGCGGCCTGGCAGAGAGACTTTCAAGCAGCTGGCTGGATGTTCGTCATATTGAAAAG
  TATGTAGACCAAGGTAAAAGTGGAACAAGAGAATTACTTTGGTCCTGGGCACAGAAAAAC
  AAGACCATCGGTGACCTTTTACAGGTCCTCCAGGAGATGGGACATCGTCGAGCTATTCAT
  TTAATTACAAACTATGGAGCAGTGTTGAGTCCTTCAGAGAAGAGTTATCAGGAAGGTGGA
  TTTCCAAATATATTATTCAAGGAAACAGCCAATGTCACCGTGGATAATGTTCTTATTCCT
  GAACATAATGAAAAAGGAGTACTGCTTAAATCTTCCATCAGCTTTCAAAATATCATAGAA
  GGAACTAGAAATTTCCACAAAGACTTCCTAATTGGAGAAGGAGAGATTTTTGAGGTATAC
  AGAGTGGAGATTCAAAACCTAACATATGCTGTCAAATTATTTAAACAGGAGAAAAAAATG
  CAGTGTAAGAAGCATTGGAAGAGGTTTTTATCTGAGCTTGAAGTTTTACTACTGTTTCAT
  CACCCAAACATACTAGAGTTGGCTGCATATTTTACAGAGACTGAGAAGTTCTGTCTGATT
  TATCCATACATGAGAAATGGAACACTTTTTGACAGATTGCAGTGTGTAGGTGACACGGCC
  CCACTCCCTTGGCACATTCGAATCGGTATATTAATAGGAATATCCAAAGCCATTCACTAC
  CTGCACAACGTTCAACCATGCTCGGTCATCTGTGGCAGTATATCAAGTGCAAACATCCTT
  TTGGATGATCAGTTTCAACCCAAACTAACTGATTTTGCCATGGCACACTTCCGGTCCCAC
  CTAGAACATCAGAGTTGTACCATAAATATGACCAGCAGCAGCAGTAAACATCTGTGGTAC
  ATGCCAGAAGAGTACATCAGACAGGGGAAACTTTCCATTAAAACAGATGTCTACAGCTTT
  GGAATTGTAATAATGGAAGTTCTAACAGGATGTAGAGTAGTGTTAGATGATCCAAAACAT
  ATCCAGCTGCGGGATCTCCTTAGAGAATTGATGGAGAAGAGAGGCCTGGATTCATGTCTC
  TCATTTCTAGATAAGAAAGTGCCTCCCTGCCCTCGGAATTTCTCTGCCAAGCTCTTCTGT
  TTGGCAGGCCGGTGTGCTGCAACGCGGGCAAAGTTAAGACCATCAATGGATGAAGTTTTA
  AATACTCTTGAAAGTACTCAAGCCAGCTTGTATTTTGCTGAAGATCCTCCCACATCACTA
  AAGTCCTTCAGGTGTCCTTCTCCTCTATTCCTGGAGAATGTACCAAGTATTCCAGTGGAA
  GATGATGAAAGCCAGAATAACAATTTACTACCTTCTGATGAAGGCCTGAGGATAGACAGA
  ATGACTCAGAAAACTCCTTTTGAATGCAGCCAGTCTGAGGTTATGTTTCTGAGCTTGGAC
  AAAAAGCCAGAGAGCAAGAGAAATGAGGAAGCTTGCAACATGCCCAGTTCTTCTTGTGAA
  GAAAGTTGGTTCCCAAAGTATATAGTTCCATCCCAGGACTTAAGGCCCTATAAGGTAAAT
  ATAGATCCTTCTTCAGAAGCTCCAGGGCATTCTTGCAGGAGCAGGCCAGTGGAGAGCAGC
  TGTTCCTCCAAATTTTCCTGGGATGAATATGAACAGTACAAAAAAGAATAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007199 unedited
  AATGTCAAAATTTGTATACGACTCACTATAGGCGGCCGCGACTTCGGCACCAGAGGCCTG
  TCGCAGGCGTGCAGGGACCTGGACTCCGCCTCGTCCCCGGGGCTCGGGCAGCCGAGCCAT
  GGCGGGGAACTGTGGGGCCCGCGGCGCGCTGTCGGCGCACACGCTGCTGTTCGACCTGCC
  GCCCGCGCTGCTCGGAGAGCTCTGCGCTGTTCTGGACAGCTGCGACGGCGCGCTGGGCTG
  GCGCGGCCTGGCAGAGAGACTTTCAAGCAGCTGGCTGGATGTTCGTCATATTGAAAAGTA
  TGTAGACCAAGGTAAAAGTGGAACAAGAGAATTACTTTGGTCCTGGGCACAGAAAAACAA
  GACCATCGGTGACCTTTTACAGGTCCTCCAGGAGATGGGACATCGTCGAGCTATTCATTT
  AATTACAAACTATGGAGCAGTGTTGAGTCCTTCAGAGAAGAGTTATCAGGAAGGTGGATT
  TCCAAATATATTATTCAAGGAAACAGCCAATGTCACCGTGGATAATGTTCTTATTCCTGA
  ACATAATGAAAAAGGAGTACTGCTTAAATCTTCCATCAGCTTTCAAAATATCATAGAAGG
  AACTAGAAATTTCCACAAAGACTTCCTAATTGGAGAAGGAGAGATTTTTGAGGTATACAG
  AGTGGAGATTCAAAACCTAACATATGCTGTCAAATTATTTAAACAGGAGAAAAAAATGCA
  GTGTAAGAAGCATTGGAAGAGGTTTTTATCTGAGCTTGAAGTTTTACTACTGTTTCATCA
  CCCAAACATACTAGAGTTGGCTGCATATTTTACAGAGACTGAGAAAGTTCTGTCTGATTT
  ATCCATACATGAGAAATGGNACACTTTTTGACAGATTTGCAGTGTGTAGTGACACGGCCC
  CACTCCTG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_007199 unedited
  GGGGGTTGGGGGGCCAAACACGAAACTTCTCCNNNNNGNNTTACNTTGNNACGCGGNNCC
  GCTTTTNANGATCGNGTTTTTTTTTTTTTTTTTTTTTTTTTTCCAAGGTATCTATTAACA
  TTTACAAATTAGACATTTCCTACAACCCGTGCAAGCAAGCTAAACCAAACGATGGAATCC
  AACTGAATGTTCTTGGCAGATGGAGGCTCTGAGGACTCACACTGAGGATGATGGAGAGGA
  CATTACAATCCAGTCCCTTTTTGGTAGGTTTTGATTGTTTTGTTTGGCTGAAGTCAAAAC
  CCATGATCTTAAGGAATTTTGAATGGCTCTAATTGAGCGTGGATTTGGTCATGAGACAAT
  TATCCTGATAAAACAATTTTTTAAGGCACTCTGTTTGAGGGTTTGGGAAAAAAGAAATGG
  AATTATCCAAATTGTTTATCTGCATCACCCAAACTCACTATTGATCATTCTCTTGGCATT
  GCTTATGGAGCCAATGTCTTCCCAAGGTCATACCTATGCTCAGGTGCCTATGCAATACTT
  GCTTTTTTCTTTATCTTCTGGTAGAATTTATTCTTTTTTGTACTGTTCATATTCATCCCA
  GGAAAATTTGGAGGAACAGCTGCTCTCCACTGGCCTGCTCCTGCAAGAATGCCCTGAAGC
  TTCTGAAGAAGGATCTATATTTACCTTATAGGGCCTTAAGTCCTGGGATGGAACTATATA
  CTTTGGGAACCAACTTTTTTTACAAAAAGAACTGGGCATGTTGCAAGCTTCCTAATTACT
  CTTGCTCTTTGGGCTTTTTGGCCAAGCTCAAAAACATAACCTCAAACTGGCTGAATTTAA
  AAAAGAGTTTTTTGGAGCATTTTTGTCTTATCCTAAGGCCTCTATCAAAAGGTAAAAAAA
  TTGTTATTCTTGCCTTTCATCATTTTCCCATGAAATACCTGGGAACCATTTCCCAGGAAA
  AAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_007199
• ORF Size: 1791 bp
• Insert Size: 2500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_007199.1, NP_009130.1
• RefSeq Size: 2288
• RefSeq ORF: 1791
• Locus ID: 11213
• Domains: DEATH, pkinase, TyrKc, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Apoptosis, Neurotrophin signaling pathway
• Gene Summary: This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.