MLLT11 (NM_006818) Human Untagged Clone

CAT#: SC115871

MLLT11 (untagged)-Human myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), translocated to, 11 (MLLT11)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MLLT11
• Synonyms: AF1Q
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115871 sequence for NM_006818 edited (data generated by NextGen Sequencing)
  ATGAGGGACCCTGTGAGTAGCCAGTACAGTTCCTTTCTTTTCTGGAGGATGCCCATCCCA
  GAACTGGATCTGTCGGAGCTGGAAGGCCTGGGTCTGTCAGATACAGCCACCTACAAGGTC
  AAAGACAGCAGCGTTGGCAAAATGATCGGGCAAGCAACTGCAGCAGACCAGGAGAAAAAC
  CCTGAAGGTGATGGCCTCCTTGAGTACAGCACCTTCAACTTCTGGAGAGCTCCCATTGCC
  AGCATCCACTCCTTCGAACTGGACTTGCTCTAA
  
  Clone variation with respect to NM_006818.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006818 unedited
  TGTAATACGACTCACTATAGGGCGGCCCGCGATTCGGCACGAGGCTTCCCTCAGTGTTCT
  GGAACCTATCATTTGAATTAGCCGAGTCAGGCAGGAGGGGGCGGGGAATCCTTCCGCCCT
  TCTTAGGAGGGGCTGCATTGCAGGGGGAGAGTGAACTGACAGACTCAGTCACTGAAGAGG
  GAAAAGGAGTGAGAAGACAAAGCCGTCAAAGCCCCAACAGCTTTGTATTTCTCCAGCCCG
  GCGCAGACCCCGGAGCTCCCGAGGCACTCCCTCCATCTTTGGAACACGCCAGTAATTGAT
  TGATAACAGGAAGCTATGAGGGACCCTGTGAGTAGCCAGTACAGTTCCTTTCTTTTCTGG
  AGGATGCCCATCCCAGAACTGGATCTGTCGGAGCTGGAAGGCCTGGGTCTGTCAGATACA
  GCCACCTACAAGGTCAAAGACAGCAGCGTTGGCAAAATGATCGGGCAAGCAACTGCAGCA
  GACCAGGAGAAAAACCCTGAAGGTGATGGCCTCCTTGAGTACAGCACCTTCAACTTCTGG
  AGAGCTCCCATTGCCAGCATCCACTCCTTCGAACTGGACTTGCTCTAAGGCCAAGACTTC
  TCTCTCCCATCACCTTGCCCTCATTGTCTTCCCTCTCAAGCCCCTTCCTTTCCACTCCTT
  TCCCATTNTAATCTTGTTCTCTCCCTACTGTGTTGGTGGTGCTGATGAATCTGCCAGAAG
  TTGAGTCTATGGATTTATTTATCTATCTGGCTACTCCATTTCTCTCAAAGCCCTCCAGTC
  ACAAAGTANATGGTTCAAGCAATGGAGTACTGGGTCACAGGGNATTCTTCTTTTCCCCCC
  CAATATTAACTNCAGAAACTANGGCTGACTGNGGGACACCTGAANAGTAATTTAGTAGTG
  GCAAATGGGAAGACTGATTTTTGACTCTATATAATCAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006818 unedited
  CACCGCGGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTGGGATTGAATGTCTT
  TATTAAATAAACGAGTAAATGGTAGCACAAATCACCATCAATATTTTTGGAAGGATTGGG
  GACAAGATGTCGAGTCAGAATATAATTGTTCATTTCAGGGTCTCAATGTAGCTGAAGAAC
  TGTGCCCACTGATCAGTATTACGTATTGCAAATGCAGGAGGTAAGGCTAAAATAGGACTT
  ATGCCGTTCAAAAGATTGAATTGAAACCTTAAAAACTATCATAATAGTAGGAATGCATGT
  TAACATTTGATAACTTTCTTTAGCTAGAGTTTTCAACCCACAGTTAGGAGCAAAGTTGTA
  AAGTGAGTACGTGTGAAGAAGGGACACTCTTTTGAGAAAAGAAATTAGCTACCTTCTAAA
  ATGATTCAATTATTTTCCCTATTTTCATTTTCCATAATATTTCCTCCTGTTTTATACCTC
  TAACTACCCTCCTGATTTCTCTGAGGAACAAAAAGAATATCAGAGCATGATCACAAAAAA
  GCAAGACACTTATCACTTTTACCCTTTTAAAAATACTGTTTTGTACCAAATAACCTCAAA
  CTAAAACTTCCCGAGGTTTCATCACCCCTTGCAAAACCATGTGCGTCTACCTGCCCTGGA
  GCACGAAATTACGAAAGCTTAAGGAATCTCTGAACCTGATTATTAAACAGATAAAAAAAT
  CCTCTTTCATTTTGGCACTACTATTACTACTCTTCAGGGGTCCCCACCCAAGCCCTACTC
  CCTGGACCTTATATTCTGGGGCGAAAAGGAGAATTCCTGGGACCCATTCTCCATGGTTGA
  ACCCTTACTTGTGACTGGGGGCCTTTCAAGACTTGCGCACACCCCTCCCCTCCTTTCCTC
  CACCCTCCTCTGCCCATTACCAGC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006818
• ORF Size: 273 bp
• Insert Size: 1680
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006818.3, NP_006809.1
• RefSeq Size: 2180
• RefSeq ORF: 273
• Locus ID: 10962
• Gene Summary: The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq, Jul 2008]