STK3 (NM_006281) Human Untagged Clone

CAT#: SC116188

STK3 (untagged)-Human serine/threonine kinase 3 (STK3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STK3
• Synonyms: KRS1; MST2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_006281 edited
  ATGGAGCAGCCGCCGGCGCCTAAGAGTAAACTAAAAAAGCTGAGTGAAGACAGTTTGACT
  AAGCAGCCTGAAGAAGTTTTTGATGTATTAGAGAAGCTTGGAGAAGGGTCTTATGGAAGT
  GTATTTAAAGCAATACACAAGGAATCCGGTCAAGTTGTCGCAATTAAACAAGTACCTGTT
  GAATCAGATCTTCAGGAAATAATCAAAGAAATTTCCATAATGCAGCAATGTGACAGCCCA
  TATGTTGTAAAGTACTATGGCAGTTATTTTAAGAATACAGACCTCTGGATTGTTATGGAG
  TACTGTGGCGCTGGCTCTGTCTCAGACATAATTAGATTACGAAACAAGACATTAATAGAA
  GATGAAATTGCAACCATTCTTAAATCTACATTGAAAGGACTAGAATATTTGCACTTTATG
  AGAAAAATACACAGAGATATAAAAGCTGGAAATATTCTCCTCAATACAGAAGGACATGCA
  AAATTGGCAGATTTTGGAGTGGCTGGTCAGTTAACAGATACAATGGCAAAACGCAATACT
  GTAATAGGAACTCCATTTTGGATGGCTCCTGAGGTGATTCAAGAAATAGGCTATAACTGT
  GTGGCCGACATCTGGTCCCTTGGCATTACTTCTATAGAAATGGCTGAAGGAAAACCTCCT
  TATGCTGATATACATCCAATGAGGGCTATTTTTATGATTCCCACAAATCCACCACCAACA
  TTCAGAAAGCCAGAACTTTGGTCCGATGATTTCACCGATTTTGTTAAAAAGTGTTTGGTG
  AAGAATCCTGAGCAGAGAGCTACTGCAACACAACTTTTACAGCATCCTTTTATCAAGAAT
  GCCAAACCTGTATCAATATTAAGAGACCTGATCACAGAAGCTATGGAGATCAAAGCTAAA
  AGACATGAGGAACAGCAACGAGAATTGGAAGAGGAAGAAGAAAATTCGGATGAAGATGAG
  CTGGATTCCCACACCATGGTGAAGACTAGTGTGGAGAGTGTGGGCACCATGCGGGCCACA
  AGCACGATGAGTGAAGGGGCCCAGACCATGATTGAACATAATAGCACGATGTTGGAATCC
  GACTTGGGGACCATGGTGATAAACAGTGAGGATGAGGAAGAAGAAGATGGAACTATGAAA
  AGAAATGCAACCTCACCACAAGTACAAAGACCATCTTTCATGGACTACTTTGATAAGCAA
  GACTTCAAGAATAAGAGTCACGAAAACTGTAATCAGAACATGCATGAACCCTTCCCTATG
  TCCAAAAACGTTTTTCCTGATAACTGGAAAGTTCCTCAAGATGGAGACTTTGACTTTTTG
  AAAAATCTAAGTTTAGAAGAACTACAGATGCGGTTAAAAGCACTGGACCCCATGATGGAA
  CGGGAGATAGAAGAACTTCGTCAGAGATACACTGCGAAAAGACAGCCCATTCTGGATGCG
  ATGGATGCAAAGAAAAGAAGGCAGCAAAACTTTTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006281 unedited
  CCGTTCAGAATTGTATACGACTCATATAGGCGGCCTGCGAATTCGCACGAGGTCGCCGTC
  CACCAGGTCCCTCTCTCTGTCCCCGGCCGCCATGGAGCAGCCGCCGGCGCCTAAGAGTAA
  ACTAAAAAAGCTGAGTGAAGACAGTTTGACTAAGCAGCCTGAAGAAGTTTTTGATGTATT
  AGAGAAGCTTGGAGAAGGGTCTTATGGAAGTGTATTTAAAGCAATACACAAGGAATCCGG
  TCAAGTTGTCGCAATTAAACAAGTACCTGTTGAATCAGATCTTCAGGAAATAATCAAAGA
  AATTTCCATAATGCAGCAATGTGACAGCCCATATGTTGTAAAGTACTATGGCAGTTATTT
  TAAGAATACAGACCTCTGGATTGTTATGGAGTACTGTGGCGCTGGCTCTGTCTCAGACAT
  AATTAGATTACGAAACAAGACATTAATAGAAGATGAAATTGCAACCATTCTTAAATCTAC
  ATTGAAAGGACTAGAATATTTGCACTTTATGAGAAAAATACACAGAGATATAAAAGCTGG
  AAATATTCTCCTCAATACAGAAGGACATGCAAAATTGGCAGATTTTGGAGTGGCTGGTCA
  GTTAACAGATACAATGGCAAAACGCAATACTGTAATAGGAACTCCATTATGGATGGCTCC
  TGAGGTGATTCAAGAGATAGGCTATAACTGTGTGGCCGACATCTGGTCCCTTGCCATTAC
  TTCTATAGAAATGGCTGAAGGAAAACCTCCTTATGCTGATATACATCCAATGAGGGCTAT
  TTTTATGATTTCCACAAATCCACCACCAACATTCAGCAAGCCAGAACTTTGGGTCCGATG
  ATTTCACCGATTTTGTTTAAAAGTGTTTGGGGGAAGCAACCTTGACACAAAGCTACTTGA
  ACACCACA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006281 unedited
  TGTACCGCGGCACGCAATCTAGTGTCGAGTTTTTTTTTTTTTTTTTTGCTGGGTGGCACA
  GTGAAATTTATTTGTCTTTATGATTTACACATAATAATTAAACACACAAAAGAAAAAACA
  CTGTCAAGATGGCCATATGTAGCTTAAGAAATGACTGGTCCCAATGCAATCATATAAATG
  TTCATTCAGCGTAAAAATGAGTTTCTTTTTAATGGTTTTAATCTTTTTTTTTTCAGTCCC
  CAAGGCTTGTACCACTCAGTACAAATGTTTTTGCTACTGGGTTATCATCAGGAACATGAT
  GTTTACCAATTCCCAGGAAATGAATAAAATCAACAGAAACATCCTGTGACAACAGAGCAC
  ATTTTCATAGAAATGAAATTGATGAGCTTATTACAGTTTGAATCAGTTCAGCTATTAGAT
  CTACACATAAAACATGAAACAATATTAACAAATTACATTTGTATTAAGCTTTTATTTAAA
  AATATTTATCACACTTTTTTGTGCAAGGGTTCCATTGATTTCTTTGGTTTTAAACACGAT
  AGATCTATTTTACCTAAATATATATAGTTCTATTTGTACCAAACATCAAAAATCAAAAAA
  ACAAAATTTCAAAGGGTAAAAATGGAATTATTGCTTCAATATAAAAAAGGCCTAGCCCAT
  TTGAGAACTACTGCCATTATTGCTTTCCTATGTGAAAAACTATCCTGGAAATCAAAGAAT
  GTACCCCATACTCTCCCCTGCAGAAAGTATAAATTGGGTTGCCCACTTATCATCATATTA
  ATATGACCCCTACCTTCACCAAAGGCATCCCTGAACTTGGCCTTTAAAATAGAAACAAAG
  CAAATAGCTTCAATACTAAGTTTACCTAAGGGATACCATAATAGCCCTATTCCACATAGG
  AATAAAATTTGTACCTAAGCCCTTATGCCGTCCAAGCACAATACCTTGGATTTCAAGTTT
  AAAACCTGGAAACCATTTATACATTTATTACGGGTTCGCTGACGAACAGAAAAACTTCTT
  TGTCCTCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006281
• Insert Size: 2730 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006281.1, NP_006272.1
• RefSeq Size: 2820 bp
• RefSeq ORF: 1476 bp
• Locus ID: 6788
• Cytogenetics: 8q22.2
• Domains: pkinase, TyrKc, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: MAPK signaling pathway
• Gene Summary: 'This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]'
  Transcript Variant: This variant (1) encodes isoform 1.