Granzyme A (GZMA) (NM_006144) Human Untagged Clone

CAT#: SC116272

GZMA (untagged)-Human granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) (GZMA)


  "NM_006144" in other vectors (7)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol GZMA
Synonyms CTLA3; HFSP
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC116272 sequence for NM_006144 edited (data generated by NextGen Sequencing)
ATGAGGAACTCCTATAGATTTCTGGCATCCTCTCTCTCAGTTGTCGTTTCTCTCCTGCTA
ATTCCTGAAGATGTCTGTGAAAAAATTATTGGAGGAAATGAAGTAACTCCTCATTCAAGA
CCCTACATGGTCCTACTTAGTCTTGACAGAAAAACCATCTGTGCTGGGGCTTTGATTGCA
AAAGACTGGGTGTTGACTGCAGCTCACTGTAACTTGAACAAAAGGTCCCAGGTCATTCTT
GGGGCTCACTCAATAACCAGGGAAGAGCCAACAAAACAGATAATGCTTGTTAAGAAAGAG
TTTCCCTATCCATGCTATGACCCAGCCACACGCGAAGGTGACCTTAAACTTTTACAGCTG
ACGGAAAAAGCAAAAATTAACAAATATGTGACTATCCTTCATCTACCTAAAAAGGGGGAT
GATGTGAAACCAGGAACCATGTGCCAAGTTGCAGGGTGGGGCAGGACTCACAATAGTGCA
TCTTGGTCCGATACTCTGAGAGAAGTCAATATCACCATCATAGACAGAAAAGTCTGCAAT
GATCGAAATCACTATAATTTTAACCCTGTGATTGGAATGAATATGGTTTGTGCTGGAAGC
CTCCGAGGTGGAAGAGACTCGTGCAATGGAGATTCTGGAAGCCCTTTGTTGTGCGAGGGT
GTTTTCCGAGGGGTCACTTCCTTTGGCCTTGAAAATAAATGCGGAGACCCTCGTGGGCCT
GGTGTCTATATTCTTCTCTCAAAGAAACACCTCAACTGGATAATTATGACTATCAAGGGA
GCAGTTTAA

Clone variation with respect to NM_006144.3
>OriGene 5' read for NM_006144 unedited
CCGCGAATTCGGCACGAGCCACAATGAGGAACTCCTATAGATTTCTGGCATCCTCTCTCT
CAGTTGTCGTTTCTCTCCTGCTAATTCCTGAAGATGTCTGTGAAAAAATTATTGGAGGAA
ATGAAGTAACTCCTCATTCAAGACCCTACATGGTCCTACTTAGTCTTGACAGAAAAACCA
TCTGTGCTGGGGCTTTGATTGCAAAAGACTGGGTGTTGACTGCAGCTCACTGTAACTTGA
ACAAAAGGTCCCAGGTCATTCTTGGGGCTCACTCAATAACCAGGGAAGAGCCAACAAAAC
AGATAATGCTTGTTAAGAAAGAGTTTCCCTATCCATGCTATGACCCAGCCACACGCGAAG
GTGACCTTAAACTTTTACAGCTGACGGAAAAAGCAAAAATTAACAAATATGTGACTATCC
TTCATCTACCTAAAAAGGGGGATGATGTGAAACCAGGAACCATGTGCCAAGTTGCAGGGT
GGGGCAGGACTCACAATAGTGCATCTTGGTCCGATACTCTGAGAGAAGTCAATATCACCA
TCATAGACAGAAAAGTCTGCAATGATCGAAATACTATAATTTTAACCCTGTGATTGGATG
AATATTGGTTTGTGCTGGAAGCCTNCGAGGTGGAAGAGACTCGTGCATGGAGATTCTGGA
AGCCTTTTGTTGTGCAAGGGTGTTNTCGGAGGGTCACTTTCTTTGCCTTGAAATAATGCG
GAACCCT
>OriGene 3' read for NM_006144 unedited
NTGTCTAGCAAATGGTTTTATTTTGTGAAAGNTATAAGNAAGCCACCAGTAAATGGAAGG
GAAACGGTTATTTAAACTGCTCCCTTGATAGTCATAATTATCCAGTTGAGGTGTTTCTTT
GAGAGAAGAATATAGACACCAGGCCCACGAGGGTCTCCGCATTTATTTTCAAGGCCAAAG
GAAGTGACCCCTCGGAAAACACCCTCGCACAACAAAGGGCTTCCAGAATCTCCATTGCAC
GAGTCTCTTCCACCTCGGAGGCTTCCAGCACAAACCATATTCATTCCAATCACAGGGTTA
AAATTATAGTGATTTCGATCATTGCAGACTTTTCTGTCTATGATGGTGATATTGACTTCT
CTCAGAGTATCGGACCAAGATGCACTATTGTGAGTCCTGCCCCACCCTGCAACTTGGCAC
ATGGTTCCTGGTTTCACATCATCCCCCTTTTTAGGTAGATGAAGGATAGTCACATATTTG
TTAATTTTTGCTTTTTCCGTCAGCTGTAAAAGTTTAAGGTCACCTTCGCGTGTGGCTGGG
TCATAGCATGGATAGGGAAACTCTTTCTTAACAAGCATTATCTGTTTTGTTGGCTCTTCC
CTGGTTATTGAGTGAGCCCCAAGAATGACCTGNGACCTTTTGTTCAAGTTACAGTGAGCT
GCAGTCAACACCCAGTCTTTTGCAATCAAAGCCCCAGCACAGATGGTTTTTTCTGTCAAG
ACTAAGTAAGGACATTGTAGGTCTTGAATGAAGGAGTACTTCATTTTCTCCCATAATTTT
TTCACAGACCTCTTTCGGGATAACCAGGAGAGAAACGACACTGAGAGAGGAGATGCCAGA
AATCTATTAGAGTTCTTCATTGTGGGTCGTGCCGAAATTCCCGCCGCCCTTAAAGGAGCG
TTTTACAAATTTTGCGGGTTACTAAACAGCTCTGCTTTATAAG
Restriction Sites NotI-NotI     
ACCN NM_006144
Insert Size 950 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_006144.2, NP_006135.1
RefSeq Size 878 bp
RefSeq ORF 789 bp
Locus ID 3001
Cytogenetics 5q11.2
Domains Tryp_SPc
Protein Families Druggable Genome, Protease, Secreted Protein
Protein Pathways Neuroactive ligand-receptor interaction
Gene Summary 'Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq, Jul 2008]'

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