RND3 (NM_005168) Human Untagged Clone

CAT#: SC116889

RND3 (untagged)-Human Rho family GTPase 3 (RND3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RND3
• Synonyms: ARHE; memB; Rho8; RhoE
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116889 sequence for NM_005168 edited (data generated by NextGen Sequencing)
  ATGAAGGAGAGAAGAGCCAGCCAGAAATTATCCAGCAAATCTATCATGGATCCTAATCAG
  AACGTGAAATGCAAGATAGTTGTGGTGGGAGACAGTCAGTGTGGAAAAACTGCGCTGCTC
  CATGTCTTCGCCAAGGACTGCTTCCCCGAGAATTACGTTCCTACAGTGTTTGAGAATTAC
  ACGGCCAGTTTTGAAATCGACACACAAAGAATAGAGTTGAGCCTGTGGGACACTTCGGGT
  TCTCCTTACTATGACAATGTCCGCCCCCTCTCTTACCCTGATTCGGATGCTGTGCTGATT
  TGCTTTGACATCAGTAGACCAGAGACCCTGGACAGTGTCCTCAAAAAGTGGAAAGGTGAA
  ATCCAGGAATTTTGTCCAAATACCAAAATGCTCTTGGTCGGCTGCAAGTCTGATCTGCGG
  ACAGATGTTAGTACATTAGTAGAGCTCTCCAATCACAGGCAGACGCCAGTGTCCTATGAC
  CAGGGGGCAAATATGGCCAAACAGATTGGAGCAGCTACTTATATCGAATGCTCAGCTTTA
  CAGTCGGAAAATAGCGTCAGAGACATTTTTCACGTTGCCACCTTGGCATGTGTAAATAAG
  ACAAATAAAAACGTTAAGCGGAACAAATCACAGAGAGCCACAAAGCGGATTTCACACATG
  CCTAGCAGACCAGAACTCTCGGCAGTTGCTACGGACTTACGAAAGGACAAAGCGAAGAGC
  TGCACTGTGATGTGA
  
  Clone variation with respect to NM_005168.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005168 unedited
  GGGTTCAGAATTTGTAATACGACTTACTATAGGGNNCGGCCGCGCAATTCGGCACGAGGG
  GCCGGTGAGGTAGTTCAGGCTTAAAACTTGTTGGAGGGGAGTAACCAGCCTGCTCCTCTC
  GCTCTCCTCCTCGTCTGCGCCGCGTTTCAGAGGTTGCCCATCAGCCTTGTGATTTATTTT
  TATATCTGCTTTTTATAAAGAGAGAAATATATATATATATATATATATATTTTTTTTCTT
  CTTAAGAGAAAATTCCTGTTCCAAGAGAAAATAAGGCAACATCAATGAAGGAGAGAAGAG
  CCAGCCAGAAATTATCCAGCAAATCTATCATGGATCCTAATCAGAACGTGAAATGCAAGA
  TAGTTGTGGTGGGAGACAGTCAGTGTGGAAAAACTGCGCTGCTCCATGTCTTCGCCAAGG
  ACTGCTTCCCCGAGAATTACGTTCCTACAGTGTTTGAGAATTACACGGCCAGTTTTGAAA
  TCGACACACAAAGAATAGAGTTGAGCCTGTGGGACACTTCGGGTTCTCCTTACTATGACA
  ATGTCCGCCCCCTCTCTTACCCTGATTCGGATGCTGTGCTGATTTGCTTTGACATCAGTA
  GACCAGAGACCCTGGACAGTGTCCTCAAAAAGTGGAAAGGTGAAATCCAGGAATTTTGTC
  CAAATACCAAAATGCTCTTGGTCGGCTGCAAGTCTGATCTGCGGACAGATGTTAGTACAT
  TAGTAGAGCTCTCCAATCACAGGCAGACGCCAGTGTCCTATGACCAGNGGGCANATATGG
  CCAAACAGATTGGAGCAGCTACTTATATCGAATGCTCAGCTNTACAGTCGGAANATAGCG
  TCAGAGACATTTTTCACGTTGCCACCTTGCCATGTGTAAATAAGACAAATAAAACGTTAA
  GCGGNACAAATCACAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005168 unedited
  TTACTCTTTTATTTTGAGNAAAAAAAAAAGTTGTTTTAATAAATACTGCGGAAACATTGA
  CCAAACAAACATACACAGTGACTTCAACAGTTTAAAAAATGCAACAAAAGTTCTGCTTTA
  TAACAGTTATAACTTATTTTCTTTTTACAATATTTAAATACAGAAAGCACTCGCCAGCTA
  TTTTGTAATACTGCCCAAAGCATAATGCTGCATCAATCAAAGCATATTATGTTGGTAAAA
  TGTCTGTATTTTATGGGAAATGACTGGAATCGAATTTTCTTGCAGAGACAAGACAAAGTG
  CTTGTAAGACATAGAACTGAGTGTTGTAATTACCTTAATCTCTCCTGCCACGATTTAAGG
  GGAGCACAGCTTCAACACTTCAAAAACGAAGCACTATCATGGGAAAGAAAGCTCGTTTTC
  AACAAGCGCCAACAATAAACAGGTCAGATCTGGTTTCTTCTCTGAAAGAATCTCTAAAAG
  GAACTGGTCAAAAATATCTGTAAACTATTTTAAATGCTTATTATTTTACGTAACAACAGA
  GACCAAGTGCTGAACACAGACCTTGGCTGCGTCTGTTCAGTGAGGTTTTAGCAATGACAC
  TCTAGAAATGCCCTAGTGTTATGTCAGGACTGAAAGTTTATCATATAATCTTNCACTAGG
  GATTCTCTAAAGCTTGGGTAAGTGGCATCTTCTCTCATCAATGTTCATTTAATGAAAAGT
  GAAATAAACCACCAGATTATCAGATGCTGTCAGTTTTGGAGCTTCAACCACAAATATAGT
  CCTTTTGCTTTGTNATTTTGGTAACTAANTTCAGACAGCTTTACTCACAAACTGGGCTTN
  CTGCTACTATTCTTTCCTTCACTCATTACCTTTTCTGGGGAAAACAGAACTACCCTTTTT
  CTCTTCTTGGGACATTTCTTGACATAAACACAGCAACCTTTTTTGATTTGGCTTTNTTTA
  ACCGTGGCAAAATAACACACACTTTAAACAGCGCCAAAATTTCCTTGGGCATTCACACTT
  TTTAGCAATCCATGGAACACAACTCGACGAATAAACGCTATTNTTCCTTTGAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005168
• Insert Size: 2950 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005168.3, NP_005159.1
• RefSeq Size: 2683 bp
• RefSeq ORF: 735 bp
• Locus ID: 390
• Cytogenetics: 2q23.3
• Domains: ras, RAS, RHO, RAB
• Gene Summary: 'This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]'
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.