RND3 (NM_005168) Human Untagged Clone

CAT#: SC322482

RND3 (untagged)-Human Rho family GTPase 3 (RND3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RND3
• Synonyms: ARHE; memB; Rho8; RhoE
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322482 GGACTTGGGAGGCGCGGTGAGGAGTCAGGCTTAAAACTTGTTGGAGGGGAGTAACCAGCC
  TGCTCCTCTCGCTCTCCTCCTCGTCTGCGCCGCGTTTCAGAGAGAAAATTCCTGTTCCAA
  GAGAAAATAAGGCAACATCAATGAAGGAGAGAAGAGCCAGCCAGAAATTATCCAGCAAAT
  CTATCATGGATCCTAATCAGAACGTGAAATGCAAGATAGTTGTGGTGGGAGACAGTCAGT
  GTGGAAAAACTGCGCTGCTCCATGTCTTCGCCAAGGACTGCTTCCCCGAGAATTACGTTC
  CTACAGTGTTTGAGAATTACACGGCCAGTTTTGAAATCGACACACAAAGAATAGAGTTGA
  GCCTGTGGGACACTTCGGGTTCTCCTTACTATGACAATGTCCGCCCCCTCTCTTACCCTG
  ATTCGGATGCTGTGCTGATTTGCTTTGACATCAGTAGACCAGAGACCCTGGACAGTGTCC
  TCAAAAAGTGGAAAGGTGAAATCCAGGAATTTTGTCCAAATACCAAAATGCTCTTGGTCG
  GCTGCAAGTCTGATCTGCGGACAGATGTTAGTACATTAGTAGAGCTCTCCAATCACAGGC
  AGACGCCAGTGTCCTATGACCAGGGGGCAAATATGGCCAAACAGATTGGAGCAGCTACTT
  ATATCGAATGCTCAGCTTTACAGTCGGAAAATAGCGTCAGAGACATTTTTCACGTTGCCA
  CCTTGGCATGTGTAAATAAGACAAATAAAAACGTTAAGCGGAACAAATCACAGAGAGCCA
  CAAAGCGGATTTCACACATGCCTAGCAGACCAGAACTCTCGGCAGTTGCTACGGACTTAC
  GAAAGGACAAAGCGAAGAGCTGCACTGTGATGTGAATCTTTCATTATCTTTAATGAAGAC
  AAAGGAATCTAGTGTAAAAAACAACAGCAAACAAAAAGGTGAAGTCTAAATGAAGTGCAC
  AGCCAAAGTCATGTATACCAGAGGCTTAGGAGGCGTTTGAGAGGATACTCATCTTTTTGG
  AATCCTGACCTTAGGTTCGGCATGTAGACCAAGTGATGAGAAGTGAATACATGGAAGAGT
  TTTTAAGTGTGACTTGAAAAATATGCCAAAAAATGAGAGATACAAATGAGCTAGAGGAAG
  ATGAGGGGGGATGCGAGTACCTCCAAGAAGAAAAATCACACTCTGAATGGTGCTTGCATT
  TTTGGGTTTTTTTTTTTTTTGTTATAATCTATTCATGGATCTCCACTTTGATTTAATTTT
  TAAATGTTTTAATCTCCTTTACAAAAAGTATACGTTAATATACCGTCCTCAAGGGGGAAC
  TGGCACTGTGACCTTAGCATTTAGTTTTCTAGAGGATGTGATCTAATTTCTTTCTAGCTC
  ATCATTAAAAAGGAAATTGTATCAGGACCCATGGGATATATCCAGAGGCAAACTTTATGA
  GGCTTTGAAATCTTGCCTTCCTGAAGATAGCTGAGTAGGATGGTTCTAAGGAAAGCCTTT
  GCAATCTTGCAAGATTTGTAGACCAGCACTACAAAGATCGCATAGATCAAATAGGAAAAA
  AAATGTCGATTTTTATTCAGTCTGATGGTTCTGTTCTTCATTGTGATTGTCATTAAAAAG
  TGGTAAATTGCTCAATGTAATATTTTTGTGCGCTGTTTAGAAGTTGTGTGATTTTTTGCC
  ATCGTTGATAAAAATGCAAAGTCAAATAAAAGGTGTCTTGGTTTGATGTCATAGAATGAT
  CCAAGGAGAGAAAAAAGGTAGTTACTGTTTTCACCAGAAAAGGTAATGAGTGAAGGAAAG
  AATAGTAGCAGAAAGCACAGTTTGTGAGTAAAGCTGTCTGGAATTAAGTTACCAAAAATA
  CAAAGCAAAAGGACTATTATTTTGGGTTGAAGCTCCAAAACTGACAGCATCTGATAATCT
  GTTGGTTTATTTCACTTTTCATTAAATGAACATTGATGAGAGAAGATGCCACTTACCCAA
  GCTTTAGAGAATCCCTAGTGGAAGATTATATGATAAACTTTCAGTCCTGACATAACACTA
  GGGCATTTCTAGAGTGTCATTGCTAAAACCTCACTGAACAGACGCAGCCAAGGTCTGTGT
  TCAGCACTTGGTCTCTGTTGTTACGTAAAATAATAAGCATTTAAAATAGTTTACAGATAT
  TTTTGACCAGTTCCTTTTAGAGATTCTTTCAGAGAAGAAACCAGATCTGACCTGTTTATT
  GTTGGCGCTTGTTGAAAACGAGCTTTCTTTCCCATGATAGTGCTTCGTTTTTGAAGTGTT
  GAAGCTGTGCTCCCCTTAAATCGTGGCAGGAGAGATTAAGGTAATTACAACACTCAGTTC
  TATGTCTTACAAGCACTTTGTCTTGTCTCTGCAAGAAAATTCGATTCCAGTCATTTCCCA
  TAAAATACAGACATTTTACCAACATAATATGCTTTGATTGATGCAGCATTATGCTTTGGG
  CAGTATTACAAAATAGCTGGCGAGTGCTTTCTGTATTTAAATATTGTAAAAAGAAAATAA
  GTTATAACTGTTATAAAGCAGAACTTTTGTTGCATTTTTTAAACTGTTGAAGTCACTGTG
  TATGTTTGTTTGGTCAATGTTTCCGCAGTATTTATTAAAACATACTTTTTTTTTTCTTCA
  AATAAAAAAGTAACCATGTCTTTGTCTAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_005168
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005168.3, NP_005159.1
• RefSeq Size: 2683 bp
• RefSeq ORF: 735 bp
• Locus ID: 390
• Cytogenetics: 2q23.3
• Domains: ras, RAS, RHO, RAB
• Gene Summary: 'This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]'
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.