AKAP5 (NM_004857) Human Untagged Clone

CAT#: SC117102

AKAP5 (untagged)-Human A kinase (PRKA) anchor protein 5 (AKAP5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AKAP5
• Synonyms: AKAP75; AKAP79; H21
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_004857 edited
  ATGGAAACCACAATTTCAGAAATTCATGTAGAAAACAAGGATGAGAAGAGATCAGCAGAA
  GGTAGTCCTGGGGCTGAAAGGCAGAAGGAAAAGGCATCCATGCTTTGCTTCAAGAGAAGA
  AAGAAAGCAGCCAAAGCACTGAAGCCCAAAGCTGGCTCTGAAGCTGCTGATGTGGCAAGG
  AAGTGTCCACAAGAAGCAGGAGCTTCTGATCAGCCAGAGCCCACACGGGGGGCCTGGGCC
  TCACTCAAACGTCTTGTAACACGCAGGAAAAGGTCAGAGTCTTCAAAGCAGCAAAAGCCA
  TTGGAGGGTGAAATGCAACCTGCAATAAATGCTGAGGATGCTGATCTTTCTAAGAAAAAG
  GCAAAATCTAGACTTAAGATTCCCTGCATAAAATTCCCAAGAGGGCCAAAAAGGAGTAAT
  CATTCCAAAATTATAGAAGACTCAGACTGCAGCATCAAAGTCCAGGAAGAAGCTGAAATT
  TTGGATATACAAACACAGACCCCATTGAATGATCAGGCAACAAAGGCTAAGTCAACCCAG
  GATCTAAGTGAAGGCATCTCACGGAAAGATGGTGATGAGGTCTGTGAATCAAATGTGAGC
  AATAGCATAACTTCTGGAGAGAAAGTGATTTCAGTAGAACTTGGATTAGATAATGGGCAT
  TCTGCTATTCAAACGGGAACTCTAATCCTTGAAGAAATTGAAACGATCAAGGAAAAACAA
  GATGTTCAACCCCAGCAAGCAAGCCCACTTGAAACTTCAGAAACAGACCATCAGCAGCCA
  GTACTTTCTGATGTTCCTCCTTTACCTGCAATTCCAGATCAACAAATTGTGGAAGAAGCC
  AGTAACAGTACCCTAGAAAGTGCACCAAATGGAAAAGACTATGAAAGTACAGAGATTGTA
  GCTGAAGAAACTAAGCCAAAAGATACTGAATTGAGCCAAGAATCAGATTTTAAAGAAAAT
  GGGATCACTGAAGAGAAATCCAAATCAGAAGAAAGCAAAAGAATGGAGCCAATTGCTATT
  ATTATTACAGACACTGAAATCAGTGAATTTGATGTTACAAAATCTAAAAATGTCCCTAAG
  CAATTCTTAATTTCAGCTGAAAATGAGCAAGTAGGGGTTTTTGCTAATGATAATGGTTTT
  GAGGATAGAACTTCAGAACAATATGAAACACTCTTAATTGAAACAGCCTCTTCTCTAGTC
  AAGAATGCTATTCAGTTGTCAATAGAACAGCTGGTTAATGAAATGGCCTCTGATGATAAT
  AAAATAAACAATCTTCTACAGTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004857 unedited
  TTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCGCGGCTCCCTGGA
  GGCCTGGGCGGCGGGCCCCGCGAGCGCGCCGCCACCTCGGGAGCAGTGTTGGCCAAGGAC
  CCCGACGCCCTACGTTGATCTTTAAATAAAGCAAAAATTTATCCAAAGAAGGGCTTTCAT
  CAAGAAATTAAAGAGAGAAATTACAAGCCATAGAGAAACTGGGCATTTCTATACTAGAGA
  AACCACCTAAAACAACTGTATGGAGTAAGATGAAAGGTATGAATATGCCTGGAAGAAATT
  TTACCTAGTGTGACATTTTTGCTCATCTTTTTGTCACAAAAGGCTGCTAAGGAAGAGAGA
  ATACAGTTTTCTAGAGAATAAGAGTGCAGTGTAAAAATGGAAACCACAATTTCAGAAATT
  CATGTAGAAAACAAGGATGAGAAGAGATCAGCAGAAGGTAGTCCTGGGGCTGAAAGGCAG
  AAGGAAAAGGCATCCATGCTTTGCTTCAAGAGAAGAAAGAAAGCAGCCAAAGCACTGAAG
  CCCAAAGCTGGCTCTGAAGCTGCTGATGTGGCAAGGAAGTGTCCACAAGAAGCAGGAGCT
  TCTGATCAGCCAGAGCCCACACGGNNGGGCCTGGNGCCTCACTCAAACGTCTTGTAACAC
  GCAGGAAAAGGTCAGAGTCTTCAAAGCAGCAAAAGCCATTGGGAGGGTGAAATGCAAACC
  TGCATAAATGCTGNAGGATGCTGATCTTTCTAAGAAAAGGGCAAATCTAGACTTAAGATT
  CCCTGCATAAAATCCCAAGAGGGCCAAANAGGGAGTATCATTCCCAAATATAGAAGACTC
  AGACTGCAGCCATCAAGTCCAGGAAGAAGCTGAATTNTNGGATATACAAACACCAGACCC
  ATTGAATGATCAGGCACC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004857
• ORF Size: 1284 bp
• Insert Size: 2630
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_004857.2, NP_004848.2
• RefSeq Size: 2601
• RefSeq ORF: 1284
• Locus ID: 9495
• Domains: PkinA_anch
• Protein Families: Druggable Genome
• Gene Summary: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. [provided by RefSeq, Jul 2008]