PEX3 (NM_003630) Human Untagged Clone

CAT#: SC117821

PEX3 (untagged)-Human peroxisomal biogenesis factor 3 (PEX3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PEX3
• Synonyms: PBD10A; PBD10B; TRG18
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117821 sequence for NM_003630 edited (data generated by NextGen Sequencing)
  ATGCTGAGGTCTGTATGGAATTTTCTGAAACGCCACAAAAAGAAATGCATCTTCCTGGGC
  ACGGTCCTTGGAGGAGTATATATTCTGGGGAAATATGGACAGAAGAAAATCAGAGAAATA
  CAGGAAAGGGAGGCTGCAGAATACATTGCCCAAGCACGACGACAATATCATTTTGAAAGT
  AACCAGAGGACTTGCAATATGACAGTGCTGTCCATGCTTCCAACACTGAGAGAGGCCTTA
  ATGCAGCAACTGAATTCCGAGAGCCTCACAGCTCTGCTAAAAAACAGGCCTTCAAACAAG
  CTAGAAATATGGGAGGATCTGAAGATAATAAGTTTCACAAGAAGTACTGTGGCTGTATAC
  AGTACCTGTATGCTGGTTGTTCTTTTGCGGGTCCAGTTAAACATAATTGGTGGATATATT
  TACCTGGATAATGCAGCAGTTGGCAAAAATGGCACTACAATTCTTGCTCCCCCAGATGTC
  CAACAGCAGTATTTATCAAGTATTCAGCACCTACTTGGAGATGGCCTGACAGAATTGATC
  ACTGTCATTAAACAAGCTGTGCAGAAGGTTTTAGGAAGTGTTTCTCTTAAACATTCTTTG
  TCCCTTTTGGACTTGGAGCAAAAACTAAAAGAAATCAGAAATCTCGTTGAGCAGCATAAG
  TCTTCTTCTTGGATTAATAAAGATGGATCCAAACCTTTATTATGCCATTATATGATGCCA
  GATGAAGAAACTCCATTAGCAGTGCAGGCCTGTGGACTTTCTCCTCGAGACATTACCACT
  ATTAAACTTCTCAATGAAACTAGAGACATGTTGGAAAGCCCAGATTTTAGTACAGTTTTG
  AATACCTGTTTAAACCGAGGTTTTAGTAGACTTTTAGACAATATGGCTGAGTTCTTTCGA
  CCTACTGAACAGGACCTGCAACATGGTAACTCTATGAATAGTCTTTCCAGTGTCAGCCTG
  CCTTTAGCTAAGATAATTCCAATAGTAAACGGACAGATCCATTCAGTTTGCAGTGAAACA
  CCTAGTCATTTTGTTCAGGATCTGTTGACAATGGAGCAAGTGAAAGACTTTGCTGCTAAT
  GTGTATGAAGCTTTTAGTACCCCTCAGCAACTGGAGAAATGA
  
  Clone variation with respect to NM_003630.2
  874 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003630 unedited
  NNNTTGTCANTTTTTGTATACGACTCCTATAGGGCGGCCGCGATTCGGCACGAGGGCGCG
  GCGGCAGCGGCAGAAAGCGTAGCTGCTTTGCTGTAGTCCACGCCCCCTTGCCGCTCCGGT
  GACAGTCTCTGCGGAAAGTCACGTTTGTGATTTCGGGAGAGCACAGAACGGGACGACGGC
  GCTCTTGCTGGGTCATCTGGGCCAGGTGACGAAGAAACAGTTTCCTGGTGAAGCAGTCCC
  TCACCCCTAGTCAGCCCACACCCCTAGGGCCTAAAGATGCTGAGGTCTGTATGGAATTTT
  CTGAAACGCCACAAAAAGAAATGCATCTTCCTGGGCACGGTCCTTGGAGGAGTATATATT
  CTGGGGAAATATGGACAGAAGAAAATCAGAGAAATACAGGAAAGGGAGGCTGCAGAATAC
  ATTGCCCAAGCACGACGACAATATCATTTTGAAAGTAACCAGAGGACTTGCAATATGACA
  GTGCTGTCCATGCTTCCAACACTGAGAGAGGCCTTAATGCAGCAACTGAATTCCGAGAGC
  CTCACAGCTCTGCTAAAAAACAGGCCTTCAAACAAGCTAGAAATATGGGAGGATCTGAAG
  ATAATAAGTTTCACAAGAAGTACTGTGGCTGTATACAGTACCTGTATGCTGGTTGTTCTT
  TTGCGGGTCCAGTTAAACATAATTGGTGGATATATTTACCTGGATAATGCAGCAGTTGGC
  AAAAATGGCACTACAATTCTTGCTCCCCCAGATGTCCAACAGCAGTATTTATCAAGTATT
  CAGCACCTACTTGGAGATGGCCTGACAGAATTGATCACTGTCATTAAACAAGCTGTGCAG
  AAGGTTNTANGNAAGTGTTTCTCTTTAACATTCTTTGTCCCTTTGGGACTTGNAGCANNA
  ACTAAAGAATCAGNAATCTCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003630 unedited
  GACCGCGGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTACTAAAATAGTTTAT
  TGCAATAAGATTTTCACTGTATTCAAAATCAATACAAAGTAAGTTTTTAAAATTATGTAC
  AAATGATTAAAACTATGTAATTAGGTGAGTAAACAGCATCAACACAATTTTAGCCTCTAA
  ACCAATATGTAACTTTCTAAGGCTTTTTAATAAAACCTTAAAAAATATAGTGAAGAAATA
  GCAAAGAACATAGTTCATCATAGTTGTTGGAATTCACTATTTCCATAAGAATAAAAAAGT
  CCTCCATCAAGGTATATTTGAGACAAATAATTTATTATTTTGAAAGGTAGCTGGAGAAAA
  GTCTGATTCACTTCTGTTTACAGCAGTCTAGGGAACATTATAATTAAATAGCATATTTTT
  CCAAACTTCACACATCCTAGACCTATGTCTCCAACAGATTTTTCCTCAGTATTAATATGG
  TAAAGTACACTGAATTTTGTATTTTTATATATATATATGTATATAAAATATCTATATTGA
  TTTTTAGTCAGTTTGGAACAAATGTCCATGTGTAACAAATTATTAACAATTCTGATATTT
  GCACGTGTATATATATATGCCCACAAAAACTGGTCTGTTGATGAATCTAAAAAAATATAT
  TAAGATGCCAAATAAATTGATTTCATTATGAAATGAAGACTTTTATTAAGAATATATTTT
  ATCAGGCATTTTGATAACANACTGTTACTCTAAGTATAGGTGATTTACCCAGTGTATTCT
  AAAAGTAAATGAATCCACTGTAGTTTTTCCTGAAGGAANAAATCACTTCTCCAGTGCTGA
  GGGGTACTANNAGCTCATACACTTAGCAGCAAGNCTTCACTTGCTCATTGCAACAGATCT
  GACAAAAGACTAGTTGTCACTGCAACTGATGGACTGTCGCTACTATGGATTACTACCTAA
  GCAGCTGACCTGAAGACTTCTAGATACCATGTGAGTCCGTN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003630
• ORF Size: 1122 bp
• Insert Size: 2100
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003630.1, NP_003621.1
• RefSeq Size: 1979
• RefSeq ORF: 1122
• Locus ID: 8504
• Domains: Peroxin-3
• Protein Families: Druggable Genome
• Gene Summary: The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS). [provided by RefSeq, Oct 2008]