PEX3 (NM_003630) Human Untagged Clone

CAT#: SC322428

PEX3 (untagged)-Human peroxisomal biogenesis factor 3 (PEX3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PEX3
• Synonyms: PBD10A; PBD10B; TRG18
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322428 CCGGTGACAGTCTCTGCGGAAAGTCACGTTTGTGATTTCGGGAGAGCACAGAACGGGACG
  ACGGCGCTCTTGCTGGGTCATCTGGGCCAGGTGACGAAGAAACAGTTTCCTGGTGAAGCA
  GTCCCTCACCCCTAGTCAGCCCACACCCCTAGGGCCTAAAGATGCTGAGGTCTGTATGGA
  ATTTTCTGAAACGCCACAAAAAGAAATGCATCTTCCTGGGCACGGTCCTTGGAGGAGTAT
  ATATTCTGGGGAAATATGGACAGAAGAAAATCAGAGAAATACAGGAAAGGGAGGCTGCAG
  AATACATTGCCCAAGCACGACGACAATATCATTTTGAAAGTAACCAGAGGACTTGCAATA
  TGACAGTGCTGTCCATGCTTCCAACACTGAGAGAGGCCTTAATGCAGCAACTGAATTCCG
  AGAGCCTCACAGCTCTGCTAAAAAACAGGCCTTCAAACAAGCTAGAAATATGGGAGGATC
  TGAAGATAATAAGTTTCACAAGAAGTACTGTGGCTGTATACAGTACCTGTATGCTGGTTG
  TTCTTTTGCGGGTCCAGTTAAACATAATTGGTGGATATATTTACCTGGATAATGCAGCAG
  TTGGCAAAAATGGCACTACAATTCTTGCTCCCCCAGATGTCCAACAGCAGTATTTATCAA
  GTATTCAGCACCTACTTGGAGATGGCCTGACAGAATTGATCACTGTCATTAAACAAGCTG
  TGCAGAAGGTTTTAGGAAGTGTTTCTCTTAAACATTCTTTGTCCCTTTTGGACTTGGAGC
  AAAAACTAAAAGAAATCAGAAATCTCGTTGAGCAGCATAAGTCTTCTTCTTGGATTAATA
  AAGATGGATCCAAACCTTTATTATGCCATTATATGATGCCAGATGAAGAAACTCCATTAG
  CAGTGCAGGCCTGTGGACTTTCTCCTCGAGACATTACCACTATTAAACTTCTCAATGAAA
  CTAGAGACATGTTGGAAAGCCCAGATTTTAGTACAGTTTTGAATACCTGTTTAAACCGAG
  GTTTTAGTAGACTTCTAGACAATATGGCTGAGTTCTTTCGACCTACTGAACAGGACCTGC
  AACATGGTAACTCTATGAATAGTCTTTCCAGTGTCAGCCTGCCTTTAGCTAAGATAATTC
  CAATAGTAAACGGACAGATCCATTCAGTTTGCAGTGAAACACCTAGTCATTTTGTTCAGG
  ATCTGTTGACAATGGAGCAAGTGAAAGACTTTGCTGCTAATGTGTATGAAGCTTTTAGTA
  CCCCTCAGCAACTGGAGAAATGATTTTTCCTTCAAGAAAAACTACAGTGGGATTCATTTA
  CTTTTTAAAATACACTGGGTAAATCACCTATACTTAGAGTAACAGTTTGTTATCAAAATG
  CCTGATAAAATATATTCTTAATAAAAGTCTTCATTTCATAATGAAAAAAAAAAAAAAAAA
  AA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322428 unedited
  TATCATTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
  GAATTCCCGGGATATCGTCGACCCACGCGTCCGCCGGTGACAGTCTCTGCGGAAAGTCAC
  GTTTGTGATTTCGGGAGAGCACAGAACGGGACGACGGCGCTCTTGCTGGGTCATCTGGGC
  CAGGTGACGAAGAAACAGTTTCCTGGTGAAGCAGTCCCTCACCCCTAGTCAGCCCACACC
  CCTAGGGCCTAAAGATGCTGAGGTCTGTATGGAATTTTCTGAAACGCCACAAAAAGAAAT
  GCATCTTCCTGGGCACGGTCCTTGGAGGAGTATATATTCTGGGGAAATATGGACAGAAGA
  AAATCAGAGAAATACAGGAAAGGGAGGCTGCAGAATACATTGCCCAAGCACGACGACAAT
  ATCATTTTGAAAGTAACCAGAGGACTTGCAATATGACAGTGCTGTCCATGCTTCCAACAC
  TGAGAGAGGCCTTAATGCAGCAACTGAATTCCGAGAGCCTCACAGCTCTGCTAAAAAACA
  GGCCTTCAAACAAGCTAGAAATATGGGAGGATCTGAAGATAATAAGTTTCACAAGAAGTA
  CTGTGGCTGTATACAGTACCTGTATGCTGGTTGTTCTTTTGCGGGTCCAGTTAAACATAA
  TTGGTGGATATATTTACCTGGATAATGCAGCAGTTGGCAAAAATGGCACTACAATTCTTG
  CTCCCCCAGATGTCCAACAGCAGTATTTATCAAGTATTCAGCACCTACTTGGAGATGGGC
  CTGACAGGAATTGATCACTGTCATTAAACAAGCTGTGCAGACGTTTTTAGGAGTGTTTTC
  TCCTTAAACATTCTTTGTCCCTCTCGACCTTGAGCAGAGCTAAGTAATCAGAATCTCATG
  GACAGCATAGTCTTCTCTTGCATTAATAGAATGGAATCCTAGCGTGTATGGCCCGTTAAT
  TGATGCCATGGAGACTCCATGACACGTACGAGGCGCTATAG
• Restriction Sites: Please inquire
• ACCN: NM_003630
• ORF Size: 1122 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_003630.1, NP_003621.1
• RefSeq Size: 1979
• RefSeq ORF: 1122
• Locus ID: 8504
• Domains: Peroxin-3
• Protein Families: Druggable Genome
• Gene Summary: The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS). [provided by RefSeq, Oct 2008]