Caspr (CNTNAP1) (NM_003632) Human Untagged Clone

CAT#: SC117823

CNTNAP1 (untagged)-Human contactin associated protein 1 (CNTNAP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CNTNAP1
• Synonyms: CASPR; CHN3; CNTNAP; NRXN4; P190
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117823 sequence for NM_003632 edited (data generated by NextGen Sequencing)
  ATGATGCATCTCCGGCTCTTCTGCATCCTGCTCGCCGCGGTCTCAGGAGCCGAGGGCTGG
  GGCTACTACGGCTGCGACGAGGAGCTGGTGGGTCCCCTGTATGCACGCTCCCTGGGCGCC
  TCCTCCTACTACAGTCTCCTTACTGCGCCGCGATTCGCCAGGCTGCACGGCATAAGCGGG
  TGGTCACCACGGATTGGGGATCCGAATCCCTGGCTCCAGATAGACTTAATGAAGAAGCAC
  CGGATCCGGGCCGTGGCCACACAGGGCTCCTTTAATTCTTGGGACTGGGTCACACGTTAC
  ATGCTACTCTACGGCGACCGAGTGGACAGCTGGACACCGTTCTACCAGCGAGGGCACAAC
  TCGACCTTCTTTGGTAACGTGAACGAGTCGGCGGTGGTGCGCCATGACCTGCACTTCCAC
  TTCACTGCGCGCTACATCCGCATCGTGCCCCTGGCCTGGAACCCACGCGGCAAGATCGGC
  CTGAGGCTCGGCCTCTATGGCTGCCCATACAAGGCCGACATACTCTATTTCGACGGCGAC
  GATGCCATCTCCTACCGCTTCCCGCGAGGGGTCAGCCGAAGCCTGTGGGACGTGTTCGCC
  TTCAGCTTCAAGACCGAGGAGAAGGACGGTCTTCTGCTGCACGCCGAGGGCGCCCAGGGC
  GACTACGTGACGCTCGAGCTGGAGGGGGCACACCTGCTGCTGCACATGAGCCTGGGCAGC
  AGCCCTATCCAGCCAAGACCAGGTCACACCACCGTGAGCGCAGGCGGAGTCCTCAATGAC
  CAGCACTGGCACTATGTGCGGGTGGACCGATTTGGCCGCGATGTAAATTTCACCCTGGAC
  GGCTATGTGCAGCGCTTTATTCTCAATGGAGACTTCGAGAGGCTGAACCTGGACACTGAG
  ATGTTCATCGGAGGTCTGGTGGGCGCCGCGCGGAAGAACCTGGCCTATCGGCATAACTTC
  CGCGGCTGCATAGAAAACGTAATCTTCAACCGCGTCAACATCGCAGACCTGGCCGTGCGG
  CGCCATTCCCGGATCACCTTCGAGGGTAAGGTGGCTTTTCGTTGCCTGGACCCGGTACCG
  CACCCTATCAACTTCGGAGGCCCTCACAACTTCGTTCAAGTGCCCGGTTTCCCACGCCGT
  GGCCGCCTGGCAGTCTCATTTCGCTTCCGCACCTGGGACCTCACCGGGCTTCTCCTTTTC
  TCCCGTCTGGGGGACGGGCTGGGCCACGTGGAGCTGACGCTCAGCGAAGGGCAGGTCAAC
  GTGTCCATCGCGCAGAGCGGCCGAAAGAAGCTTCAGTTCGCTGCTGGGTACCGACTGAAT
  GACGGCTTTTGGCACGAGGTGAATTTTGTGGCACAGGAAAACCATGCAGTTATCAGCATT
  GATGATGTGGAAGGGGCAGAGGTCAGGGTCTCATACCCGTTGCTGATCCGGACAGGGACC
  TCATATTTCTTTGGGGGTTGTCCCAAGCCAGCCAGTCGATGGGACTGCCACTCCAACCAG
  ACGGCATTCCATGGCTGCATGGAGCTGCTCAAGGTGGATGGTCAACTGGTCAACCTGACT
  CTGGTGGAGGGCCGGCGGCTTGGATTCTATGCTGAGGTCCTCTTTGATACATGTGGCATC
  ACTGATAGGTGCAGCCCTAACATGTGTGAGCATGATGGACGCTGCTACCAGTCTTGGGAT
  GACTTCATTTGCTACTGCGAACTGACGGGCTACAAGGGAGAGACCTGCCACACACCTTTG
  TATAAGGAATCCTGTGAGGCTTATCGGCTCAGTGGGAAAACTTCTGGAAACTTCACCATT
  GATCCTGATGGCAGTGGCCCCCTGAAGCCATTTGTAGTGTACTGTGATATCCGAGAGAAC
  CGAGCGTGGACAGTTGTGCGGCATGACAGGCTGTGGACAACTCGAGTGACAGGTTCCAGC
  ATGGAGCGGCCATTCCTGGGGGCTATCCAGTACTGGAATGCATCCTGGGAGGAAGTCAGT
  GCCCTTGCCAATGCTTCCCAGCATTGTGAACAGTGGATCGAGTTCTCCTGCTACAATTCC
  CGGCTGCTCAACACTGCAGGAGGCTACCCCTACAGCTTTTGGATTGGCCGAAATGAGGAG
  CAGCACTTCTACTGGGGAGGCTCCCAGCCTGGGATCCAGCGCTGTGCCTGTGGTCTGGAC
  CGGAGCTGTGTGGACCCTGCCTTGTACTGCAACTGTGACGCTGACCAGCCCCAGTGGAGA
  ACTGACAAGGGACTGCTGACCTTTGTGGACCATCTGCCTGTCACTCAGGTAGTGATAGGG
  GATACGAACCGCTCCACTTCTGAGGCCCAGTTCTTCCTGAGGCCTCTGCGCTGCTATGGC
  GATCGAAATTCCTGGAACACCATTTCCTTCCACACCGGGGCTGCACTACGCTTCCCCCCA
  ATCCGTGCCAACCACAGCCTGGATGTCTCCTTCTACTTCAGGACCTCTGCTCCCTCGGGG
  GTCTTCCTAGAGAATATGGGGGGCCCTTACTGCCAGTGGCGCCGACCTTATGTGCGGGTG
  GAACTCAACACATCCCGGGATGTGGTCTTCGCCTTTGATGTGGGGAATGGGGATGAGAAC
  CTCACAGTACACTCAGACGACTTTGAGTTCAATGATGACGAGTGGCACCTGGTCCGGGCT
  GAAATCAACGTGAAGCAGGCCCGGCTCCGAGTGGATCACCGGCCCTGGGTTCTGCGGCCT
  ATGCCACTGCAGACCTACATCTGGATGGAGTATGACCAGCCCCTCTATGTGGGATCTGCA
  GAGCTTAAGAGACGCCCCTTTGTGGGTTGCTTGAGGGCCATGCGTCTGAACGGAGTGACT
  CTGAACCTGGAGGGCCGTGCCAATGCCTCTGAGGGTACCTCACCCAACTGCACAGGCCAC
  TGTGCCCACCCTCGGCTCCCCTGTTTCCATGGAGGCCGCTGCGTGGAGCGCTATAGCTAC
  TACACGTGTGACTGTGACCTCACGGCTTTTGATGGGCCATACTGCAACCACGATATTGGT
  GGTTTCTTTGAGCCGGGCACCTGGATGCGCTATAACCTACAGTCAGCGCTGCGCTCTGCA
  GCCAGGGAGTTCTCCCACATGCTGAGCCGGCCAGTGCCAGGCTATGAGCCTGGCTACATC
  CCGGGCTATGATACTCCGGGCTATGTGCCTGGCTACCATGGCCCCGGGTACCGCCTGCCC
  GACTACCCCCGGCCTGGTCGGCCTGTGCCCGGTTACCGTGGGCCTGTCTACAACGTTACG
  GGAGAGGAGGTCTCCTTCAGCTTCAGCACCAGCTCCGCCCCTGCTGTCCTGCTCTACGTC
  AGTTCCTTTGTTCGTGACTACATGGCTGTGCTCATCAAGGATGATGGGACCCTTCAGCTG
  CGATATCAGCTGGGCACCAGTCCCTACGTGTACCAGCTAACCACTCGACCAGTGACCGAT
  GGCCAGCCCCATAGCATCAATATCACCCGTGTTTACCGGAACCTCTTCATCCAGGTGGAC
  TACTTCCCACTGACAGAGCAGAAGTTCTCGCTGTTGGTGGACAGCCAGTTGGACTCACCC
  AAGGCCTTGTATTTAGGGCGTGTGATGGAGACAGGAGTCATTGACCCGGAGATCCAGCGC
  TACAACACCCCAGGTTTCTCAGGCTGCCTGTCTGGTGTTCGATTCAACAACGTGGCTCCC
  CTCAAGACCCACTTCCGAACCCCTCGACCCATGACTGCTGAGCTAGCTGAGGCCCTTCGA
  GTTCAGGGAGAACTGTCCGAATCTAATTGCGGAGCTATGCCACGTCTTGTTTCAGAGGTG
  CCACCTGAGCTTGATCCCTGGTATCTGCCCCCAGACTTCCCCTACTACCATGATGAAGGA
  TGGGTTGCCATACTTTTAGGCTTTTTGGTGGCCTTTCTGCTGCTGGGGCTGGTGGGAATG
  TTGGTGCTCTTCTATCTGCAAAATCATCGCTATAAGGGCTCCTACCATACCAATGAGCCC
  AAGGCTGCCCACGAGTACCATCCTGGCAGCAAACCTCCCCTACCCACTTCAGGCCCTGCC
  CAGGTCCCCACCCCTACAGCAGCTCCCAACCAAGCTCCAGCCTCAGCCCCAGCCCCAGCC
  CCAACTCCAGCCCCAGCCCCTGGCCCCCGGGATCAGAACCTACCCCAGATCCTGGAGGAG
  TCCAGGTCTGAATGA
  
  Clone variation with respect to NM_003632.2
  151 a=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003632 unedited
  NTTATTACCCCCGCCCGTTGNCGCAAAGGGCGGTAGGCGTGTACGGTGGGAGGTCTATAT
  AAGCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGC
  CGCGAATTCGGCACGAGGAGAGAGCGGTCTGCTGCAAACCCCAGGAGGAGAGCTTGGAGC
  CCAAGCCAGAACTCGAGCCCTAGCCGGAGCCGTTCACAGGGAGGCGGCTGCCGGGACCGT
  CAGCCCTGCATGATGCATCTCCGGCTCTTCTGCATCCTGCTCGCCGCGGTCTCAGGAGCC
  GAGGGCTGGGGCTACTACGGCTGCGACGAGGAGCTGGTGGGTCCCCTGTATGCACGCTCC
  CTGNGCGCCTCCTCCTACTACAGTCTCCTTACTGCGCCGCGATTCGCCAGGCTGCACGGC
  ATAAGCGGGTGGTCACCACGGATTGNGGATCCGAATCCCTGGCTCCAGATAGACTTAATG
  AAGAAGCACCGGATCCGGGCCGTGGCCACACAGGGCTCCTTTAATTCTTGGGACTGGGTC
  ACACGTTACATGCTACTCTACGGCGACCGAGTGGACAGCTGGACACCGTTCTACCAGCGA
  GGGCACAACTCGACCTTCTTTGGGTACGTGAACGAGTCGGCGGTGGTGCGCCATGACCTG
  CACTTCACTTCACTGCGCGCTACATCCGCATCGTGCCCCTGGCCTGGAACCCNACGCGCC
  AGATCGGCCTGAGGGCTCGGCTCTATGGCTGCCCATACCAGGCCGACATACTCTATTTCG
  ACGGCGACGATGCCATCTNCTACCGCTTTCCCGCGAGGGGTCAGCCGCAGCCTGTGGGGA
  CGTGGTCGCCTTCAGCTTCAGAACCGAGAGAAGGACNGTCTTCTGCTGCACGCCGAGGGC
  GCCCAGGCGACTACNTGACGCTCGAGCTGGAGGGGCAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003632 unedited
  ATGGGTCACAGGGGATGCCACCCGAGCTCTGTTAAGAAAACACCATTGACCGCGGCCGTT
  ATCTATAAATCAAGTTTTTAAAATTTCGAATAAGGGCTAGAGTCCCTCGCTTGAGACGCT
  CGGCTCCACATAATATATCTCAAGAATCTGACCCCCGGTGTAAATGAAACTTCTTCTCAG
  ACCGGAGGAAAGAGGGTTCCTCATGCACTGGAGGGGGCTAATCCTTTGGGCAGGCACAAA
  GGCCATTGCATATCTTGGAAAAGGTTGGAGGAGTAGAGGGCTGGCTAGTCAGGGTATCTG
  CATTATTTTCTCTACGTTGCAAGTTTTTTATGGCTTTGGCTAAAGCAAGTGAAGCAGCGG
  AGGTACTAAGGTGCTAAACTGAGGCCTCTTGGTCTCTGTGTACAAAACAAAAGGAGGGGG
  GCAGGGGACAGCCATCAAGCCCTCTTGAGCCTCCATCTGAGTGGAATCAAATGGAATATC
  TTCANGGCAGGGGGGAGGCTGGGGGATAGGGTTTAACANCCTCCTCCCCCCATACCCTCT
  GCAGCCCTGCACTCCCACACATCTGTCCCTGCTGATAGTGTCTATTGGAAGGGAGGCAGT
  TAATCTCCCCTACACTCTGTTGTTAATCCCTGACAGCCGCTGGAACAGAGATGGCAGAAA
  GGACCTATGTCAACCCCATGAGGCTTCTCCTTTGGGGCATATAAACAGCCAGAGCCTGGG
  GGAAACAGGGTGATAAGGGCATTTGGTTAAGCAGTGAAGCCTGGCCACCTCCTTGGGTCC
  CATCTGTAGCTCTGCCACCCAAATTTGAGGGGGGGGGATGGGGGGAATTTTCTTTAGGAA
  GAACAAACCAC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003632
• ORF Size: 4155 bp
• Insert Size: 6000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003632.1, NP_003623.1
• RefSeq Size: 5293
• RefSeq ORF: 4155
• Locus ID: 8506
• Domains: F5_F8_type_C, LamG, EGF
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• Gene Summary: The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. [provided by RefSeq, Jan 2009]