CD13 (ANPEP) (NM_001150) Human Untagged Clone

CAT#: SC119422

ANPEP (untagged)-Human alanyl (membrane) aminopeptidase (ANPEP)


  "NM_001150" in other vectors (6)

Reconstitution Protocol

SC119422 is the updated version of SC125423.

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ANPEP
Synonyms APN; CD13; GP150; LAP1; P150; PEPN
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for NM_001150 edited
GAATTCGGCACGAGCCAGTGCTGGAGGGGCAGGGACGGCGGCGGCGCAGCTCGGAACCCG
CCAGGGTCCAGGGTCCAGGTTCCAGCGCCCGGCGGCCCAGCTCTCAAGCAGATCAATGCA
ATGCCACCTGGCCGCTTGCTTTGCCCACTGGGCCTACAGCCGGAAGCCTGCCCTTCAGCC
CTCGGGCCTGATCCCAGGCCGCCTGCAGCCTGTAACCAGACACTGTTTGCTTCCAGCAGG
CACCCCCCGAGCCCAGCTCCACACACCGTTCCTGGATCTCCTCTCCCCAGGCGGAGCGTG
CCCCTGCCCAGTCCAGCGACCTTCGCCTGTTGGAGCCCTGGTTAATTTTTGCCCAGTCTG
CCTGTTGTGGGGCTCCTCCCCTTTGGGGATATAAGCCCGGCCTGGGGCTGCTCCGTTCTC
TGCCTGGCCTGAGGCTCCCTGAGCCGCCTCCCCACCATCACCATGGCCAAGGGCTTCTAT
ATTTCCAAGTCCCTGGGCATCCTGGGGATCCTCCTGGGCGTGGCAGCCGTGTGCACAATC
ATCGCACTGTCAGTGGTGTACTCCCAGGAGAAGAACAAGAACGCCAACAGCTCCCCCGTG
GCCTCCACCACCCCGTCCGCCTCAGCCACCACCAACCCCGCCTCGGCCACCACCTTGGAC
CAAAGTAAAGCGTGGAATCGTTACCGCCTCCCCAACACGCTGAAACCCGATTCCTACCAG
GTGACGCTGAGACCGTACCTCACCCCCAATGACAGGGGCCTGTACGTTTTTAAGGGCTCC
AGCACCGTCCGTTTCACCTGCAAGGAGGCCACTGATGTCATCATCATCCACAGCAAGAAG
CTCAACTACACCCTCAGCCAGGGGCACAGGGTGGTCCTGCGTGGTGTGGGAGGCTCCCAG
CCCCCCGACATTGACAAGACTGAGCTGGTGGAGCCCACCGAGTACCTGGTGGTGCACCTC
AAGGGCTCCCTGGTGAAGGACAGCCAGTATGAGATGGACAGCGAGTTCGAGGGGGAGTTG
GCAGATGACCTGGCGGGCTTCTACCGCAGCGAGTACATGGAGGGCAATGTCAGAAAGGTG
GTGGCCACTACACAGATGCAGGCTGCAGATGCCCGGAAGTCCTTCCCATGCTTCGATGAG
CCGGCCATGAAGGCCGAGTTCAACATCACGCTTATCCACCCCAAGGACCTGACAGCCCTG
TCCAACATGCTTCCCAAAGGTCCCAGCACCCCACTTCCAGAAGACCCCAACTGGAATGTC
ACTGAGTTCCACACCACGCCCAAGATGTCCACGTACTTGCTGGCCTTCATTGTCAGTGAG
TTCGACTACGTGGAGAAGCAGGCATCCAATGGTGTCTTGATCCGGATCTGGGCCCGGCCC
AGTGCCATTGCGGTGGGCCACGGCGATTATGCCCTTAACGTGACAGGCCCCATCCTTAAC
TTCTTTGCTGGTCATTATGACACACCCTACCCACTCCCAAAATCAGACCAGATTGGCCTG
CCAGACTTCAACGCCGGCGCCATGGAGAACTGGGGACTGGTGACCTACCGGGAGAACTCC
CTGCTGTTCGACCCCCTGTCCTCCTCCAGCAGCAACAAGGAGCGGGTGGTCACTGTGATT
GCTCATGAGCTGGCCCACCAGTGGTTCGGGAACCTGGTGACCATAGAGTGGTGGAATGAC
CTGTGGCTGAACGAGGGCTTCGCCTCCTACGTGGAGTACCTGGGTGCTGACTATGCGGAG
CCCACCTGGAACTTGAAAGACCTCATGGTGCTGAATGATGTGTACCGCGTGATGGCAGTG
GATGCACTGGCCTCCTCCCACCCGCTGTCCACACCCGCCTCGGAGATCAACACGCCGGCC
CAGATCAGTGAGCTGTTTGACGCCATCTCCTACAGCAAGGGCGCCTCAGTCCTCAGGATG
CTCTCCAGCTTCCTGTCCGAGGACGTATTCAAGCAGGGCCTGGCGTCCTACCTCCACACC
TTTGCCTACCAGAACACCATCTACCTGAACCTGTGGGACCACCTGCAGGAGGCTGTGAAC
AACCGGTCCATCCAACTCCCCACCACCGTGCGGGACATCATGAACCGCTGGACCCTGCAG
ATGGGCTTCCCGGTCATCACGGTGGATACCAGCACGGGGACCCTTTCCCAGGAGCACTTC
CTCCTTGACCCCGATTCCAATGTTACCCGCCCCTCAGAATTCAACTACGTGTGGATTGTG
CCCATCACATCCATCAGAGATGGCAGACAGCAGCAGGACTACTGGCTGATAGATGTAAGA
GCCCAGAACGATCTCTTCAGCACATCAGGCAATGAGTGGGTCCTGCTGAACCTCAATGTG
ACGGGCTATTACCGGGTGAACTACGACGAAGAGAACTGGAGGAAGATTCAGACTCAGCTG
CAGAGAGACCACTCGGCCATCCCTGTCATCAATCGGGCACAGATCATTAATGACGCCTTC
AACCTGGCCAGTGCCCATAAGGTCCCTGTCACTCTGGCGCTGAACAACACCCTCTTCCTG
ATTGAAGAGAGACAGTACATGCCCTGGGAGGCCGCCCTGAGCAGCCTGAGCTACTTCAAG
CTCATGTTTGACCGCTCCGAGGTCTATGGCCCCATGAAGAACTACCTGAAGAAGCAGGTC
ACACCCCTCTTCATTCACTTCAGAAATAATACCAACAACTGGAGGGAGATCCCAGAAAAC
CTGATGGACCAGTACAGCGAGGTTAATGCCATCAGCACCGCCTGCTCCAACGGAGTTCCA
GAGTGTGAGGAGATGGTCTCTGGCCTTTTCAAGCAGTGGATGGAGAACCCCAATAATAAC
CCGATCCACCCCAACCTGCGGTCCACCGTCTACTGCAACGCTATCGCCCAGGGCGGGGAG
GAGGAGTGGGACTTCGCCTGGGAGCAGTTCCGAAATGCCACACTGGTCAATGAGGCTGAC
AAGCTCCGGGCAGCCCTGGCCTGCAGCAAAGAGTTGTGGATCCTGAACAGGTACCTGAGC
TACACCCTGAACCCGGACTTAATCCGGAAGCAGGACGCCACCTCTACCATCATCAGCATT
ACCAACAACGTCATTGGGCAAGGTCTGGTCTGGGACTTTGTCCAGAGCAACTGGAAGAAG
CTTTTTAACGATTATGGTGGTGGCTCGTTCTCCTTCTCCAACCTCATCCAGGCAGTGACA
CGACGATTCTCCACCGAGTATGAGCTGCAGCAGCTGGAGCAGTTCAAGAAGGACAACGAG
GAAACAGGCTTCGGCTCAGGCACCCGGGCCCTGGAGCAAGCCCTGGAGAAGACGAAAGCC
AACATCAAGTGGGTGAAGGAGAACAAGGAGGTGGTGCTCCAGTGGTTCACAGAAAACAGC
AAATAGTCCCCAGCCCTTGAAGTCACCCGGCCCCGATGCAAGGTGCCCACATGTGTCCAT
CCCAGCGGCTGGTGCAGGGCCTCCATTCCTGGAGCCCGAGGCACCAGTGTCCTCCCCTCA
AGGACAAAGTCTCCAGCCCACGTTCTCTCTGCCTGTGAGCCAGTCTAGTTCCTGATGACC
CAGGCTGCCTGAGCACCTCCCAGCCCCTGCCCCTCATGCCAACCCCGCCCTAGGCCTGGC
ATGGCACCTGTCGCCCAGTGCCCTGGGGCTGATCTCAGGGAAGCCCAGCTCCAGGGCCAG
ATGAGCAGAAGCTCTCGATGGACAATGAACGGCCTTGCTGGGGGCCGCCCTGTACCCTCT
TTCACCTTTCCCTAAAGACCCTAAATCTGAGGAATCAACAGGGCAGCAGATCTGTATATT
TTTTTCTAAGAGAAAATGTAAATAAAGGATTTCTAGATGAAAAAAAAAAAAAAAAAAAAC
TCGAC
>OriGene 5' read for NM_001150 unedited
GGGCGGGGGGNANAANACANTCNCCCCCCCGGGTTCAAAATTGTATACGATCATATAGGG
CGGCCGCGAATCGGCACGAGCCAGTGCTGGAGGGGCAGGGACGGCGGCGGCGCAGCTCGG
AACCCGCCAGGGTCCAGGGTCCAGGTTCCAGCGCCCGGCGGCCCAGCTCTCAAGCAGATC
AATGCAATGCCACCTGGCCGCTTGCTTTGCCCACTGGGCCTACAGCCGGAAGCCTGCCCT
TCAGCCCTCGGGCCTGATCCCAGGCCGCCTGCAGCCTGTAACCAGACACTGTTTGCTTCC
AGCAGGCACCCCCCGAGCCCAGCTCCACACACCGTTCCTGGATCTCCTCTCCCCAGGCGG
AGCGTGCCCCTGCCCAGTCCAGCGACCTTCGCCTGTTGGAGCCCTGGTTAATTTTTGCCC
AGTCTGCCTGTTGTGGGGCTCCTCCCCTTTGGGGATATAAGCCCGGCCTGGGGCTGCTCC
GTTCTCTGCCTGGCCTGAGGCTCCCTGAGCCGCCTCCCCACCATCACCATGGCCAAGGGC
TTCTATATTTCCAAGTCCCTGGGCATCCTGGGGATCCTCCTGGGCGTGGCAGCCGTGTGC
ACAATCATCGCACTGTCAGTGGTGTACTCCCAGGAGAAGAACAAGAACGCCAACAGCTCC
CCCGTGGCCTCCACCACCCCGTCCGCCTCAGCCACCACCAACCCCGCCTCGGCCACCACC
TTGGNACCAAAGTAAGCGTGGAATCGTTACCGCCTCCCCACACGCTGAAACCCGATTCCT
ACCAGGTGACGCTGAGACCGTACCTCACCCCCCATGACAGGGGCCTGTACGTTNNTAAGG
GCTNCAGCACCGTCCGTTTCACCTGCAGGGAGGCCACTGATGTCATCATCATCCCACAGC
AGAAGCTCAACTACACCCTCANCAGGGGCACAGGGTGGTTCTGCGTGGA
>OriGene 3' read for NM_001150 unedited
CGGGGCCNNNNNNNCCTTCNNNNANNAAGATTTGAACCCGGCCGCATTCTANGATCGGTT
TTTTTTTTTTTTTTTTTTCATCAAAAAACCTTTATTTACATTTTCTCTTAGAAAAAAAAT
ACAGATCTGCTGCCCTGTTGATTCCTCAAATTTAGGGTCTTTAGGGAAAGGTGAAAGAGG
GTACAGGGCGGCCCCCAGCAAGGCCGTTCATTGTCCATCGAGAGCTTCTGCTCATCTGGC
CCTGGAGCTGGGCTTCCCTGAGATCAGCCCCAGGGCACTGGGCGACAGGTGCCATGCCAG
GCCTAGGGCGGGGTTGGCATGAGGGGCAGGGGCTGGGAGGTGCTCAGGCAGCCTGGGTCA
TCAGGAACTAGACTGGCTCACAGGCAGAGAGAACGTGGGCTGGAGACTTTGTCCTTGAGG
GGAGGACACTGGTGCCTCGGGCTCCAGGAATGGAGGCCCTGCACCAGCCGCTGGGATGGA
CACATGTGGGCACCTTGCATCGGGGCCGGGTGACTTCAAGGGCTGGGGACTATTTGCTGT
TTTCTGTGAACCACTGGAGCACCACCTCCTTGTTCTCCTTCACCCACTTGATGTTGGCTT
TCGTCTTCTCCAGGGCTTGCTCCAGGGCCCGGGTGCCTGAGCCGAAGCCTGTTTCCTCGT
TGNCCTTCTTGAACTGCTCCAGCTGCTGCAGCTCATACCTCGTGGAGAATCGTCGTGTCA
CTGCCTGAATGAGGNTGGAGAAGGAGAACGAGCCACCACCATATCGTTAAAAGCTTCTTN
CAGTTGCTCTGGNACAAGTCCNAGACCAGACTTGCCCATGACGNTGNTNGTAATGCTGAT
GATGGGAAAGGTGGCGTCCTGCTTCCCGGATTAGTCCGGNTNCNGGGTGTAGCTCAGGTA
CCCTGTCAGGATCCACCACTCTTTGCTGCAGCCAGGGCTTGCCNGGACTTGCCACCTCAT
GAACACTGTGGCATTTCGGACTGCTCAAGGCGAATCCCACTCTCCTCCCGCCTGGGCGAT
G
Restriction Sites NotI-NotI     
ACCN NM_001150
Insert Size 3750 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001150.1, NP_001141.1
RefSeq Size 3494 bp
RefSeq ORF 2904 bp
Locus ID 290
Cytogenetics 15q26.1
Domains Peptidase_M1
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Protease, Transmembrane
Protein Pathways Glutathione metabolism, Hematopoietic cell lineage, Metabolic pathways, Renin-angiotensin system
Gene Summary 'Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. This membrane-bound zinc metalloprotease is known to serve as a receptor for the HCoV-229E alphacoronavirus as well as other non-human coronaviruses. This gene has also been shown to promote angiogenesis, tumor growth, and metastasis and defects in this gene are associated with various types of leukemia and lymphoma. [provided by RefSeq, Apr 2020]'

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