RGS18 (NM_130782) Human Untagged Clone

CAT#: SC120407

RGS18 (untagged)-Human regulator of G-protein signaling 18 (RGS18)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RGS18
• Synonyms: RGS13
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_130782, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAAACAACATTGCTTTTCTTTTCTCAAATAAATATGTGTGAATCAAAAGAAAAAACTTTTTTCAAGT
  TAATACATGGTTCAGGAAAAGAAGAAACAAGCAAAGAAGCCAAAATCAGAGCTAAGGAAAAAAGAAATAG
  ACTAAGTCTTCTTGTGCAGAAACCTGAGTTTCATGAAGACACCCGCTCCAGTAGATCTGGGCACTTGGCC
  AAAGAAACAAGAGTCTCCCCTGAAGAGGCAGTGAAATGGGGTGAATCATTTGACAAACTGCTTTCCCATA
  GAGATGGACTAGAGGCTTTTACCAGATTTCTTAAAACTGAATTCAGTGAAGAAAATATTGAATTTTGGAT
  AGCCTGTGAAGATTTCAAGAAAAGCAAGGGACCTCAACAAATTCACCTTAAAGCAAAAGCAATATATGAG
  AAATTTATACAGACTGATGCCCCAAAAGAGGTTAACCTTGATTTTCACACAAAAGAAGTCATTACAAACA
  GCATCACTCAACCTACCCTCCACAGTTTTGATGCTGCACAAAGCAGAGTGTATCAGCTCATGGAACAAGA
  CAGTTATACACGTTTTCTGAAATCTGACATCTATTTAGACTTGATGGAAGGAAGACCTCAGAGACCAACA
  AATCTTAGGAGACGATCACGCTCATTTACCTGCAATGAATTCCAAGATGTACAATCAGATGTTGCCATTT
  GGTTATAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_130782 unedited
  CAAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAAATTCGCACCANAAGAAACGCA
  GCTCTTGACTTCTTTTTTGTAAACATTACTGTAAGAGTTGTGATAACTTTTTATTCTACT
  ATGTATATGTATGGAATAGTATTAATAAATGAACTAGGGAAGGATGTAATAAATTAGACA
  TCTCTTCATTTTAGAGAGAAGATGGAAACAACATTGCTTTTCTTTTCTCAAATAAATATG
  TGTGAATCAAAAGAAAAAACTTTTTTCAAGTTAATACATGGTTCAGGAAAAGAAGAAACA
  AGCAAAGAAGCCAAAATCAGAGCTAAGGAAAAAAGAAATAGACTAAGTCTTCTTGTGCAG
  AAACCTGAGTTTCATGAAGACACCCGCTCCAGTAGATCTGGGCACTTGGCCAAAGAAACA
  AGAGTCTCCCCTGAAGAGGCAGTGAAATGGGGTGAATCATTTGACAAACTGCTTTCCCAT
  AGAGATGGACTAGAGGCTTTTACCAGATTTCTTAAAACTGAATTCAGTGAAGAAAATATT
  GAATTTTGGATAGCCTGTGAAGATTTCAAGAAAAGCAAGGGACCTCAACAAATTCACCTT
  AAAGCAAAAGCAATATATGAGAAATTTATACAGACTGATGCCCCAAAAGAGGTTAACCTT
  GATTTTCACACAAAAGAAGTCATTACAAACAGCATCACTCAACCTACCCTCCACAGTTTT
  GATGCTGCACAAAGCAGAGTGTATCAGCTCATGGAACAAGACAGTTATACACGTTTTCTG
  AAATCTGACATCTATTTAGACTTGATGGAAATTCTTTCACTTCATTATATGCAAGTTTCA
  ATATTANGTCTAAGTGAGTTTTAAGGGTACTGATGACTTACAATATGGGCTCTGATGGGC
  ATACTCATTNGAGTCCTTCCATTGACCTATTTACTGGTGAAAATTAAGTGAAATCTGGGC
  TCATCTTTAAGCTTACTATAAGATNTN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_130782
• ORF Size: 708 bp
• Insert Size: 2650
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_130782.2, NP_570138.1
• RefSeq Size: 2158
• RefSeq ORF: 708
• Locus ID: 64407
• Domains: RGS
• Gene Summary: This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]