RGS18 (NM_130782) Human Untagged Clone

CAT#: SC321112

RGS18 (untagged)-Human regulator of G-protein signaling 18 (RGS18)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RGS18
• Synonyms: RGS13
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_130782.2 ATTTCTGCAGAGACAGAAAGAAACGCAGCTCTTGACTTCTTTTTTGTAAACATTACTGTA
  AGAGTTGTGATAACTTTTTATTCTACTATGTATATGTATGGAATAGTATTAATAAATGAA
  CTAGGGAAGGATGTAATAAATTAGACATCTCTTCATTTTAGAGAGAAGATGGAAACAACA
  TTGCTTTTCTTTTCTCAAATAAATATGTGTGAATCAAAAGAAAAAACTTTTTTCAAGTTA
  ATACATGGTTCAGGAAAAGAAGAAACAAGCAAAGAAGCCAAAATCAGAGCTAAGGAAAAA
  AGAAATAGACTAAGTCTTCTTGTGCAGAAACCTGAGTTTCATGAAGACACCCGCTCCAGT
  AGATCTGGGCACTTGGCCAAAGAAACAAGAGTCTCCCCTGAAGAGGCAGTGAAATGGGGT
  GAATCATTTGACAAACTGCTTTCCCATAGAGATGGACTAGAGGCTTTTACCAGATTTCTT
  AAAACTGAATTCAGTGAAGAAAATATTGAATTTTGGATAGCCTGTGAAGATTTCAAGAAA
  AGCAAGGGACCTCAACAAATTCACCTTAAAGCAAAAGCAATATATGAGAAATTTATACAG
  ACTGATGCCCCAAAAGAGGTTAACCTTGATTTTCACACAAAAGAAGTCATTACAAACAGC
  ATCACTCAACCTACCCTCCACAGTTTTGATGCTGCACAAAGCAGAGTGTATCAGCTCATG
  GAACAAGACAGTTATACACGTTTTCTGAAATCTGACATCTATTTAGACTTGATGGAAGGA
  AGACCTCAGAGACCAACAAATCTTAGGAGACGATCACGCTCATTTACCTGCAATGAATTC
  CAAGATGTACAATCAGACGTTGCCATTTGGTTATAAAGAAAATTGATTTTGCTCATTTTT
  ATGACAAACTTATACATCTGCTTCTAACATATCGCATGTTTATGTTAAGATTTGGTCCCA
  TCCTTTAAACTGAAATATGTCATGTGAAATTATTTTAAAAATGTAAAAACAAAACTTTCT
  GCTAACAAAATACATACAGTATCTGCCAGTATATTCTGTAAAACCTTCTATTTGATGTCA
  TTCCATTTATAATCAGAAAAAAAACTTATTTCTTAATCAAAAGGCAGTACAAAAAAAGTA
  ATAATGTTTTATAAGATTGTAGAGTTAAGTAAAAGTTAAGCTTTTGCAAAGTTGTCAAAA
  GTTCAAACAAAAGTCTAGTTGGGATTTTTTACCAAAGCAGCATAATATGTGTTATATAAA
  CATAATAATACTCAGATATCCAAATGTTCAGATAGCATTTTTCATAATGAATGTTCTCTT
  TTTTTTGGTAATAGTGTAGAAGTGATCTGGTTCTTACAATGGGAGATGAAGAACATTTAT
  TATTGGGTTACTACTAACCCTGTCCCAAGAATAGTAATATCACCTCTAGTTATAAGCCAG
  CAACAGGAACTTTTGTGAAGACACATTCATCTCTACGGAACTTCAGATTAAATATAATCT
  AGATTAATGACTGAGAATAAGATCCACATTTGAACTCATTCCTAAGTGAACATGGACGTA
  CCCAGTTATACAAAGTACTTCTGTTGGTCACAGAAACATGACCAGATTTTGCATATCTCC
  AGGTAGGGAACTAAGTAGACTACCTTATCACCGGCTAAGAAAACTTGCTACTAAACTATT
  AGGCCATCAATGGCTTGAATAAAAACCAGAGAAGGTTTTTCCCAGGACGTCTCATGTTTG
  GCCCTTTAGAATTGGGGTAGAAATCAGAAATGAGATGAGGGGAAGAAGCAAGGAGTCTAA
  GGCCCTAGCGATTTGGGCATCTGCCACATTGGTTCATATTCAGAAAGTGTTATCTCATTG
  ATTATATTCTTGTTAAGCAAATCTCCTTAAGTAATTATTATTCAAATAAGATTATACTCA
  TACATCTATATGTCACTGTTTTAAAGAGATATTTAATTTTTAATGTGTGTTACATGGTCT
  GTAAATATTTGTATTTAAAAATGCCATGCATTAGGCTTTGGAAATTTAATGTTAGTTGAA
  ATGTAAAATGTGAAAACTTTAGATCATTTGTAGTAATAAATATTTTTAACTTCATTCATA
  CAGTTAAGTTTATCTGACAATAAAAGCTCTGACTAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_130782.2 unedited
  TGCCATTGTATACGACTCCTATAGGGCGGCCGCGAATTCGGCCATTACGGCCGGGGATTT
  CTGCAGAGACAGAAAGAAACGCAGCTCTTGACTTCTTTTTTGTAAACATTACTGTAAGAG
  TTGTGATAACTTTTTATTCTACTATGTATATGTATGGAATAGTATTAATAAATGAACTAG
  GGAAGGATGTAATAAATTAGACATCTCTTCATTTTAGAGAGAAGATGGAAACAACATTGC
  TTTTCTTTTCTCAAATAAATATGTGTGAATCAAAAGAAAAAACTTTTTTCAAGTTAATAC
  ATGGTTCAGGAAAAGAAGAAACAAGCAAAGAAGCCAAAATCAGAGCTAAGGAAAAAAGAA
  ATAGACTAAGTCTTCTTGTGCAGAAACCTGAGTTTCATGAAGACACCCGCTCCAGTAGAT
  CTGGGCACTTGGCCAAAGAAACAAGAGTCTCCCCTGAAGAGGCAGTGAAATGGGGTGAAT
  CATTTGACAAACTGCTTTCCCATAGAGATGGACTAGAGGCTTTTACCAGATTTCTTAAAA
  CTGAATTCAGTGAAGAAAATATTGAATTTTGGATAGCCTGTGAAGATTTCAAGAAAAGCA
  AGGGACCTCAACAAATTCACCTTAAAGCAAAAGCAATATATGAGAAATTTATACAGACTG
  ATGCCCCAAAAGAGGTTAACCTTGATTTTCACACAAAAGAAGTCATTACAAACAGCATCA
  CTCAACCTACCCTCCACAGTTTTGATGCTGCACAAAGCAGAGTGTATCAGCTCATGGAAC
  AAGACAGTTATACACGTTTTCTGAAATCTGACATCTATTTAGACTTGATGGAAGAGACCT
  CAGAGACCAACAAATCTTAGGAGACGATCACGCTCATTACTGCATGATCAGATGTACATC
  AGACGTGCATTTGGTTATAAAGAAAATGATTTTGCTCATTTTTATGAACAAACTTATACA
  TTCTGCTTCT
• Restriction Sites: Please inquire
• ACCN: NM_130782
• ORF Size: 708 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_130782.2, NP_570138.1
• RefSeq Size: 2158
• RefSeq ORF: 708
• Locus ID: 64407
• Domains: RGS
• Gene Summary: This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]