KIR2.3 (KCNJ4) (NM_152868) Human Untagged Clone

CAT#: SC123919

KCNJ4 (untagged)-Human potassium inwardly-rectifying channel, subfamily J, member 4 (KCNJ4), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNJ4
• Synonyms: HIR; HIRK2; HRK1; IRK-3; IRK3; Kir2.3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC123919 sequence for NM_152868 edited (data generated by NextGen Sequencing)
  ATGCACGGACACAGCCGCAACGGCCAGGCCCACGTGCCCCGGCGGAAGCGCCGCAACCGC
  TTCGTCAAGAAGAACGGCCAATGCAACGTGTACTTCGCCAACCTGAGCAACAAGTCGCAG
  CGCTACATGGCGGACATCTTCACCACCTGCGTGGACACGCGCTGGCGCTACATGCTCATG
  ATCTTCTCCGCGGCCTTCCTTGTCTCCTGGCTCTTTTTCGGCCTCCTCTTCTGGTGTATC
  GCCTTCTTCCACGGTGACCTGGAGGCCAGCCCAGGGGTGCCTGCGGCGGGGGGCCCGGCG
  GCGGGTGGTGGCGGAGCAGCCCCGGTGGCCCCCAAGCCCTGCATCATGCACGTGAACGGC
  TTCCTGGGTGCCTTCCTGTTCTCGGTGGAGACGCAGACGACCATCGGCTATGGGTTCCGG
  TGCGTGACAGAGGAGTGCCCGCTGGCAGTCATCGCTGTGGTGGTCCAGTCCATCGTGGGC
  TGCGTCATCGACTCCTTCATGATTGGCACCATCATGGCCAAGATGGCGCGGCCCAAGAAG
  CGGGCGCAGACGTTGCTGTTCAGCCACCACGCGGTCATTTCGGTGCGCGACGGCAAGCTC
  TGCCTCATGTGGCGCGTGGGCAACCTGCGCAAGAGCCACATTGTGGAGGCCCACGTGCGG
  GCCCAGCTCATCAAGCCCTACATGACCCAGGAGGGCGAGTACCTGCCCCTGGACCAGCGG
  GACCTCAACGTGGGCTATGACATCGGCCTGGACCGCATCTTCCTGGTGTCGCCCATCATC
  ATTGTCCACGAGATCGACGAGGACAGCCCGCTTTATGGCATGGGCAAGGAGGAGCTGGAG
  TCGGAGGACTTTGAGATCGTGGTCATCCTGGAGGGCATGGTGGAGGCCACGGCCATGACC
  ACCCAGGCCCGCAGCTCCTACCTGGCCAGCGAGATCCTGTGGGGCCACCGCTTTGAGCCT
  GTGGTCTTCGAGGAGAAGAGCCACTACAAGGTGGACTACTCGCGTTTTCACAAGACCTAC
  GAGGTGGCCGGCACGCCCTGCTGCTCGGCCCGGGAGCTGCAGGAGAGTAAGATCACCGTG
  CTGCCCGCCCCACCGCCCCCTCCCAGTGCCTTCTGCTACGAGAACGAGCTGGCCCTTATG
  AGCCAGGAGGAAGAGGAGATGGAGGAGGAGGCAGCTGCGGCGGCCGCGGTGGCCGCAGGC
  CTGGGCCTGGAGGCGGGTTCCAAGGAGGAGGCGGGCATCATCCGGATGCTGGAGTTCGGC
  AGCCACCTGGACCTGGAGCGCATGCAGGCTTCCCTCCCGCTGGACAACATCTCCTACCGC
  AGGGAGTCTGCCATCTGA
  
  Clone variation with respect to NM_152868.1
  1002 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_152868 unedited
  CCACTGCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGGAGCGGCGCGGGACGGCCGG
  GACGCGCGGAGACCCCAAGACCCACGCGCAGACCGAGCGGCAGCCGGGGAGGGGAGCGCG
  GGCCGGCCGGCCGAGTTCGCGGGCAGGGGGCGCCGGGACTCCCCTCTCCGCGCCCGGGAC
  GCCGCCCGCCGGATCGCGCCTTGGGATGTAGCGCCCGCTCGGCGCCTCCCGGACTCTCGT
  CGGACCCTCCGCCCAGCGGCCCTGCGTCTTCCCAGGTGACCACGCCGGCTTCAGGACATG
  CACGGACACAGCCGCAACGGCCAGGCCCACGTGCCCCGGCGGAAGCGCCGCAGCCGCTTC
  GTCAAGAAGAACGGCCAATGCAACGTGTACTTCGCCAACCTGAGCAACAAGTCGCAGCGC
  TACATGGCGGACATCTTCACCACCTGCGTGGACACGCGCTGGCGCTACATGCTCATGATC
  TTCTCCGCGGCCTTCCTTGTCTCCTGGCTCTTTTTCGGCCTCCTCTTCTGGTGTATCGCC
  TTCTTCCACGGTGACCTGAAGGCCATCCCACGGGTGCCTGCGGCGGTGGGCCCGGCAGCG
  GGTGGTGGCGGATCAGCCCCGGTGGCCCCCAAGCCCTGCATCATGCACGTGAACGGCTTC
  CTGGGTGCCTTCCTGTTCTCGGTGGAGACGCACACGACCATCGGCTATGGGTTCCGGTGC
  GTGACAGACGAGTGCCCGCTGGCAGTCATCGCTGTGGN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_152868 unedited
  TCCAGGCCAGGATAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTCAGG
  AAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTGTTTTTTTTTTTTTTT
  TTTTTTTGGGGGCTCCATCTGTCTCCATTTATAGATATTTACAAAAGAAAGTCATGAGCA
  ACAGGCCACAGTCATGCAAAAGAAACGCACCCCCCCTCCCCAAACTAACCCCCTGCCCAC
  CCTGAAACCCCGAGATGTCCCCCGCCCAGCAGTCCAGCCACCTTCCCCAAGGTTCTGAGA
  GCAAAGAGGGCACGTCCTTGAAGAGTCAGTGGGGGAAGGGTGGTGGATCCGGGGACCTAG
  AGCCACCAGAAGTAGGCGCTGGCGGAACTCAGGCTGATCGGGGCCGAGCTCTTCCCAGGC
  CTGGGTGCTGGAGTCAGGAGGAAGGGGTCCCCCAGTCTTTGAAACCCCCACCTTCCTCCA
  GAAGGTCCACGGAGCCAGGGTTGGCTCTGTCCTGAGTGTGGGAGGGGGTGTCCTGGCATC
  CCACCCCCGGCAGAGGCTCTTGTGGGCAGTGGTGAGGGCCGGGCCTGGAGGTCAGATGGC
  AGACTCCCTGCGGTAGGAGATGTTGTCCAGCGGGAGGGAAGCCTGCGTGCGCTCCAGGTC
  CAGGTGGCTGCCGAACTTCAGCATCCGGGTGATGCCCGCCTCCTCCTTTGGACCCGGCTT
  CAGGCCCAGGCCTGGGGCCACCGCGGCCGCCGCAGCTGCC
  
• Restriction Sites: Please inquire
• ACCN: NM_152868
• Insert Size: 4600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_152868.1, NP_690607.1
• RefSeq Size: 2063 bp
• RefSeq ORF: 1338 bp
• Locus ID: 3761
• Cytogenetics: 22q13.1
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane
• Gene Summary: 'Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.