Ubiquilin (UBQLN1) (NM_053067) Human Untagged Clone

CAT#: SC124352

UBQLN1 (untagged)-Human ubiquilin 1 (UBQLN1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UBQLN1
• Synonyms: DA41; DSK2; PLIC-1; UBQN; XDRP1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_053067, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCGAGAGTGGTGAAAGCGGCGGTCCTCCGGGCTCCCAGGATAGCGCCGCCGGAGCCGAAGGTGCTG
  GCGCCCCCGCGGCCGCTGCCTCCGCGGAGCCCAAAATCATGAAAGTCACCGTGAAGACCCCGAAGGAAAA
  GGAGGAATTCGCCGTGCCCGAGAATAGCTCCGTCCAGCAGTTTAAGGAAGAAATCTCTAAACGTTTTAAA
  TCACATACTGACCAACTTGTGTTGATATTTGCTGGAAAAATTTTGAAAGATCAAGATACCTTGAGTCAGC
  ATGGAATTCATGATGGACTTACTGTTCACCTTGTCATTAAAACACAAAACAGGCCTCAGGATCATTCAGC
  TCAGCAAACAAATACAGCTGGAAGCAATGTTACTACATCATCAACTCCTAATAGTAACTCTACATCTGGT
  TCTGCTACTAGCAACCCTTTTGGTTTAGGTGGCCTTGGGGGACTTGCAGGTCTGAGTAGCTTGGGTTTGA
  ATACTACCAACTTCTCTGAACTACAGAGTCAGATGCAGCGACAACTTTTGTCTAACCCTGAAATGATGGT
  CCAGATCATGGAAAATCCCTTTGTTCAGAGCATGCTCTCAAATCCTGACCTGATGAGACAGTTAATTATG
  GCCAATCCACAAATGCAGCAGTTGATACAGAGAAATCCAGAAATTAGTCATATGTTGAATAATCCAGATA
  TAATGAGACAAACGTTGGAACTTGCCAGGAATCCAGCAATGATGCAGGAGATGATGAGGAACCAGGACCG
  AGCTTTGAGCAACCTAGAAAGCATCCCAGGGGGATATAATGCTTTAAGGCGCATGTACACAGATATTCAG
  GAACCAATGCTGAGTGCTGCACAAGAGCAGTTTGGTGGTAATCCATTTGCTTCCTTGGTGAGCAATACAT
  CCTCTGGTGAAGGTAGTCAACCTTCCCGTACAGAAAATAGAGATCCACTACCCAATCCATGGGCTCCACA
  GACTTCCCAGAGTTCATCAGCTTCCAGCGGCACTGCCAGCACTGTGGGTGGCACTACTGGTAGTACTGCC
  AGTGGCACTTCTGGGCAGAGTACTACTGCGCCAAATTTGGTGCCTGGAGTAGGAGCTAGTATGTTCAACA
  CACCAGGAATGCAGAGCTTGTTGCAACAAATAACTGAAAACCCACAACTGATGCAAAACATGTTGTCTGC
  CCCCTACATGAGAAGCATGATGCAGTCACTAAGCCAGAATCCTGACCTTGCTGCACAGATGCAGAATCCT
  GATACACTATCAGCAATGTCAAACCCTAGAGCAATGCAGGCCTTGTTACAGATTCAGCAGGGTTTACAGA
  CATTAGCAACGGAAGCCCCGGGCCTCATCCCAGGGTTTACTCCTGGCTTGGGGGCATTAGGAAGCACTGG
  AGGCTCTTCGGGAACTAATGGATCTAACGCCACACCTAGTGAAAACACAAGTCCCACAGCAGGAACCACT
  GAACCTGGACATCAGCAGTTTATTCAGCAGATGCTGCAGGCTCTTGCTGGAGTAAATCCTCAGCTACAGA
  ATCCAGAAGTCAGATTTCAGCAACAACTGGAACAACTCAGTGCAATGGGATTTTTGAACCGTGAAGCAAA
  CTTGCAAGCTCTAATAGCAACAGGAGGTGATATCAATGCAGCTATTGAAAGGTTACTGGGCTCCCAGCCA
  TCATAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_053067 unedited
  NGGTTTCANATTTTGTAAACGACTCACTATAGGCGGCCGCGNAATTCGCACGAGGGGAAG
  GGGCAGGGAGGAGGAAGCGGTGGCTGCTGCGGATGTCGGTGTGAGCGAGCGGCGCCTGAA
  CACACGGCGGCTGCCGAGCGCCTGACCCGGGCCTGCGCCAGAGCCTGCACCGAGCTCCGG
  GGCCCCACACCCGCTACCGTGGCCCTGCGCCCGTTGCTACTGAGGCGGCGTGCTCTGCAT
  TCTTCGCTGTCCAGGCCTGCCGGCTCTGGTGTCTGCTGGCTCCTCCTTGCTCGCCTGCTC
  CCTCCTGCTTGCCTGAGTCACCGCCGCCGCCGCCGCCACAGCCATGGCCGAGAGTGGTGA
  AAGCGGCGGTCCTCCGGGCTCCCAGGATAGCGCCGCCGGAGCCGAAGGTGCTGGCGCCCC
  CGCGGCCGCTGCCTCCGCGGAGCCCAAAATCATGAAAGTCACCGTGAAGACCCCGAAGGA
  AAAGGAGGAATTCGCCGTGCCCGAGAATAGCTCCGTCCAGCAGTTTAAGGAAGAAATCTC
  TAAACGTTTTAAATCACATACTGACCAACTTGTGTTGATATTTGCTGGAAAAATTTTGAA
  AGATCAAGATACCTTGAGTCAGCATGGAATTCATGATGGACTTACTGTTCACCTTGTCAT
  TAAAACACAAAACAGGCCTCAGGATCATTCAGCTCAGCAAACAAATACAGCTGGAAGCAA
  TGTTACTACATCATCAACTCCTAATAGTAACTCTACATCTGGTTCTGCTACTAGCAACCC
  TTTTGGTTTAGGTGGCCTTGGNGGACNNTGCAGTCTGAGTAGCTGGNNGTTGAATACTAC
  CAACTTCTCTGAACTACAGAGTCAGATGCAGCGACAACTNNTGTCTACCCTGAATGATGG
  TCCAGATCATGGAAATCCTTNNGTNAGAGCAT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_053067
• ORF Size: 1686 bp
• Insert Size: 3900
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_053067.1, NP_444295.1
• RefSeq Size: 2354
• RefSeq ORF: 1686
• Locus ID: 29979
• Domains: UBA, UBQ, STI1
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) is missing an alternate 3' coding exon, compared to transcript variant 1. The resulting protein (isoform 2) is 28 aa shorter when compared to isoform 1.